FoxP3 Antibody [Biotin]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, IHC, IHC-Fr
Please see the vial label for concentration. If unlisted please contact technical services.

FoxP3 Antibody [Biotin] Summary

A synthetic peptide made to the C-terminal region of human FOXP3 (between residues 400-431). [UniProt# Q9BZS1]
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
Biotin (A=N/A, E=N/A)
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This FOXP3 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on frozen sections and Western Blot. By Western blot, this antibody recognizes bands at ~47.2 kDa representing FOXP3. For IHC-Fr it has been used in mouse thymus from an influenza-infected mouse or thymus from healthy mice (C57BL/6).

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
47.2 kDa
Readout System

Reactivity Notes

Human. This antibody does not appear to detect the mouse FOXP3 protein by western blot, but does work on mouse tissue for IHC (see data below).

Alternate Names for FoxP3 Antibody [Biotin]

  • AIID
  • AIIDMGC141961
  • forkhead box P3
  • Forkhead Box Protein P3
  • FOXP3delta7
  • immune dysregulation, polyendocrinopathy, enteropathy, X-linked
  • Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked
  • IPEX
  • JM2
  • MGC141961
  • MGC141963
  • PIDX
  • PIDXMGC141963
  • XPID
  • XPIDpolyendocrinopathy, enteropathy, X-linked


FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis. FOXP3 is stably and constitutively expressed at a high level in CD25 + CD4 positive regulatory T cells, a low level in CD4-positive/CD25-negative cells, and is absent in CD4-negative/CD8-positive T cells. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for FoxP3 Antibody (NB600-245B). (Showing 1 - 3 of 3 FAQ).

  1. Does FoxP3 antibodies comes in lyophilized form?
    • FoxP3 antibodies, aka JM2 IPEX, and Scurfin antibodies, have the following products in lyophilized form: NBP1-18319, AF3240.
  2. What the theoretical molecular weight for FoxP3 antibodies?
    • The TMW of FoxP3 antibodies is approximately 47 - 52 kDa.
  3. What is the immunogen sequence of this FoxP3 antibody?
    • A synthetic sequence of amino acids 400 - 431 within the C-terminal region of Human FoxP3.

Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 488 Labeled NB600-245G
DyLight 550 Labeled NB600-245R
DyLight 650 Labeled NB600-245C
HRP Labeled NB600-245H

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Blogs on FoxP3.

Is has been established that the regulatory transcription factor FOXP3 (a member of the forkhead/winged-helix family of transcription factors) is imperative to immune system homeostasis through CD4+CD25+ regulatory T cell function.  Distinctively,...  Read full blog post.

FOXP3: Master Regulatory Transcriptional Factor
FOXP3, a forkhead family transcription factor specially expressed in regulatory T (Treg) cells, controls the expression of many key immune-regulatory genes. Treg cells are a population of T lymphocytes that have critical roles in the immune system hom...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol FOXP3

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