TLRs Signaling Interactive Pathway

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Toll-like receptors (TLRs) are a class of pattern recognition receptor proteins and recognize molecules that are broadly shared by pathogens but distinguishable from host molecules. TLRs are membrane-spanning, non-catalytic and usually expressed in sentinel cells such as macrophages and dendritic cells. TLRs participate in the first line of defense against invading pathogens and play a significant role in inflammation, immune cell regulation, survival, and proliferation.

Find available products by clicking on key proteins in this interactive pathway below:

tlr pathway

Explore Your Pathways With Novus Explorer! This free bioinformatics tool is designed to facilitate scientific exploration of related genes, diseases and pathways based on co-citations.

Webinar: View our webinar on TLR Signaling Pathways in Immunity and Beyond on YouTube and download the slides from the TLR webinar

Download Our TLR Handbook