Human CD25/IL-2R alpha Quantikine ELISA Kit



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Reactivity HuSpecies Glossary
Applications ELISA

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Human CD25/IL-2R alpha Quantikine ELISA Kit Summary

The Quantikine Human IL-2 sR alpha Immunoassay is a 3.5 hour solid phase ELISA designed to measure IL-2 sR alpha in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human IL-2 sR alpha and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant factor. Results obtained using natural human IL-2... sR alpha showed linear curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-2 sR alpha.
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Natural and recombinant human IL-2 sR alpha
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DR2A00.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CD25/IL-2R alpha Quantikine ELISA Kit

  • CD25 antigen
  • CD25
  • IDDM10
  • IL-2 R alpha
  • IL-2 receptor subunit alpha
  • IL2R alpha
  • IL-2R subunit alpha
  • IL2R
  • IL2RA
  • IL-2Ra
  • IL-2-RA
  • IL2-RA
  • interleukin 2 receptor, alpha
  • interleukin-2 receptor subunit alpha
  • p55
  • TAC antigen


CD25/IL-2 receptor alpha is a transmembrane protein that associates with IL-2 R beta/CD122 and the Common gamma Chain/CD132 on activated T cells and regulatory T cells (Treg). The Common gamma chain is a shared subunit in the receptors for IL-4, -7, -9, -15, and -21. IL-2 R alpha is required for mediating IL-2 induced effects including T cell proliferation, activation induced cell death (AICD) of autoreactive naive T cells, and the development of CD4+CD25+ Treg which contribute to peripheral T cell homeostasis. A soluble form of IL-2 R alpha can be generated by proteolytic cleavage of the cell surface receptor.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for CD25/IL-2R alpha (DR2A00)(36)

We have publications tested in 4 confirmed species: Human, Mouse, Primate - Papio cynocephalus (Yellow Baboon), Xenograft.

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Primate - Papio cynocephalus (Yellow Baboon)
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Showing Publications 1 - 10 of 36. Show All 36 Publications.
Publications using DR2A00 Applications Species
K Ernzen, C Melvin, L Yu, C Phelps, S Niewiesk, PL Green, AR Panfil The PRMT5 inhibitor EPZ015666 is effective against HTLV-1-transformed T-cell lines in vitro and in vivo Frontiers in Microbiology, 2023-02-02;14(0):1101544. 2023-02-02 [PMID: 36819050] (Xenograft) Xenograft
M Trujillo-R, E Muñoz-Muel, A Serna-Gall, JM Praena-Fer, A Pérez-Góme, C Gasca-Capo, J Vitallé, J Peraire, ZR Palacios-B, JJ Cabrera, E Ruiz-Mateo, E Poveda, LE López-Cort, A Rull, A Gutierrez-, LF López-Cort Clinical, laboratory data and inflammatory biomarkers at baseline as early discharge predictors in hospitalized SARS-CoV-2 infected patients PLoS ONE, 2022-07-14;17(7):e0269875. 2022-07-14 [PMID: 35834501] (Human) Human
DB Rosen, EA Murphy, RS Gejman, A Capili, RL Friedlande, S Rand, KA Cagino, SM Glynn, KC Matthews, JM Kubiak, J Yee, M Prabhu, LE Riley, YJ Yang Cytokine response over the course of COVID-19 infection in pregnant women Cytokine, 2022-04-25;154(0):155894. 2022-04-25 [PMID: 35490452] (Human) Human
S Buhelt, HB Søndergaar, MR Mahler, S Cobanovic, L Börnsen, C Ammitzbøll, AB Oturai, F Sellebjerg Biomarkers of systemic inflammation, soluble IL-2Ralpha and the multiple sclerosis-associated IL2RA SNP rs2104286 in healthy subjects and multiple sclerosis patients Multiple sclerosis and related disorders, 2021-07-07;54(0):103140. 2021-07-07 [PMID: 34304016] (Human) Human
S Xu, H Li, P Qiao, G Xu, D Zhao, X Lin, Y Qin, H Yu, X Zhang, W Zhang, L Huang Neonatal hand, foot, and mouth disease due to coxsackievirus A6 in Shanghai BMC Pediatr, 2020-08-03;20(1):364. 2020-08-03 [PMID: 32741368] (Human) Human
M Herrera, C Vera, Y Keynan, ZV Rueda Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review J Immunol Res, 2020-04-21;2020(0):8074183. 2020-04-21 [PMID: 32377537] (Human) Human
T Gayden, FE Sepulveda, DA Khuong-Qua, J Pratt, ET Valera, A Garrigue, S Kelso, F Sicheri, LG Mikael, N Hamel, A Bajic, R Dali, S Deshmukh, D Dervovic, D Schramek, F Guerin, M Taipale, H Nikbakht, J Majewski, D Moshous, J Charlebois, S Abish, C Bole-Feyso, P Nitschke, B Bader-Meun, D Mitchell, C Thieblemon, M Battistell, S Gravel, VH Nguyen, R Conyers, JS Diana, C McCormack, HM Prince, M Besnard, S Blanche, PG Ekert, S Fraitag, WD Foulkes, A Fischer, B Neven, D Michonneau, G de Saint B, N Jabado Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome Nat. Genet., 2018-10-29;0(0):. 2018-10-29 [PMID: 30374066] (Human) Human
B Ribba, C Boetsch, TK Nayak, HP Grimm, JM Charo, S Evers, C Klein, JJL Tessier, JE Charoin, A Phipps, P Pisa, V Teichgräbe Prediction of the optimal dosing regimen using a mathematical model of tumour uptake for immunocytokine-based cancer immunotherapy Clin. Cancer Res., 2018-02-20;0(0):. 2018-02-20 [PMID: 29463551] (Human) Human
LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa Reevaluation of immune activation in the era of cART and an aging HIV-infected population JCI Insight, 2017-10-19;2(20):. 2017-10-19 [PMID: 29046481] (Human) Human
Incidence and Risk Factors for Developing Dengue-Associated Hemophagocytic Lymphohistiocytosis in Puerto Rico, 2008 - 2013 PLoS Negl Trop Dis, 2016-08-24;10(8):e0004939. 2016-08-24 [PMID: 27556807] (Human) Human
Show All 36 Publications.

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Gene Symbol IL2RA