Mouse IL-17 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse IL-17 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il17a

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DY421 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-17 DuoSet ELISA, 15 Plate

  • CTLA8
  • CTLA-8
  • CTLA8cytotoxic T-lymphocyte-associated serine esterase 8
  • Cytotoxic T-lymphocyte-associated antigen 8
  • IL17
  • IL-17
  • IL17A
  • IL-17A
  • IL-17Acytotoxic T-lymphocyte-associated protein 8
  • IL-17CTLA-8
  • IL17interleukin-17A
  • interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • interleukin 17A

Background

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

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DY421
Species: Mu
Applications: ELISA

Publications for IL-17/IL-17A (DY421)(142)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: ELISA Standard.


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ELISA Standard
(1)
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Mouse
(138)
Rat
(4)
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Showing Publications 1 - 10 of 142. Show All 142 Publications.
Publications using DY421 Applications Species
N Taghipour, N Mosaffa, HA Aghdaei, M Rostami-Ne, JV Weinstock, S Shahnavaz, MR Zali Immunomodulatory effect of Syphacia obvelata in treatment of experimental DSS-induced colitis in mouse model Sci Rep, 2019;9(1):19127. 2019 [PMID: 31836772] (Mouse) Mouse
A Suhail, ZA Rizvi, P Mujagond, SA Ali, P Gaur, M Singh, V Ahuja, A Awasthi, CV Srikanth DeSUMOylase SENP7-Mediated Epithelial Signaling Triggers Intestinal Inflammation via Expansion of Gamma-Delta T Cells Cell Rep, 2019;29(11):3522-3538.e7. 2019 [PMID: 31825833] (Mouse) Mouse
MC de Rezende, JMP Moreira, LLM Fernandes, VF Rodrigues, D Negrão-Cor Strongyloides venezuelensis-infection alters the profile of cytokines and liver inflammation in mice co-infected with Schistosoma mansoni Cytokine, 2019;127(0):154931. 2019 [PMID: 31783260] (Mouse) Mouse
JM O'Hara, NS Redhu, E Cheung, NG Robertson, I Patik, SE Sayed, CM Thompson, M Herd, KB Lucas, E Conaway, CC Morton, DL Farber, R Malley, BH Horwitz Generation of protective pneumococcal-specific nasal resident memory CD4+ T cells via parenteral immunization Mucosal Immunol, 2019;0(0):. 2019 [PMID: 31659300] (Mouse) Mouse
W Zhou, Y Yang, C Mei, P Dong, S Mu, H Wu, Y Zhou, Y Zheng, F Guo, JQ Yang Inhibition of Rho-Kinase Downregulates Th17 Cells and Ameliorates Hepatic Fibrosis by Schistosoma japonicum Infection Cells, 2019;8(10):. 2019 [PMID: 31623153] (Mouse) Mouse
N Kaushansky, E Bakos, S Becker-Her, I Shachar, A Ben-Nun Circulating Picomolar Levels of CCL2 Downregulate Ongoing Chronic Experimental Autoimmune Encephalomyelitis by Induction of Regulatory Mechanisms J. Immunol., 2019;0(0):. 2019 [PMID: 31484731] (Mouse) Mouse
MCG Miranda, RP Oliveira, L Torres, SLF Aguiar, N Pinheiro-R, L Lemos, MA Guimarães, D Reis, T Silveira, Ê Ferreira, TG Moreira, DC Cara, TU Maioli, BL Kelsall, D Carlos, AMC Faria Frontline Science: Abnormalities in the gut mucosa of non-obese diabetic mice precede the onset of type 1 diabetes J. Leukoc. Biol., 2019;0(0):. 2019 [PMID: 31313381] (Mouse) Mouse
JQ Yang, KW Kalim, Y Li, Y Zheng, F Guo Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammation J. Leukoc. Biol., 2019;0(0):. 2019 [PMID: 31260596] (Mouse) Mouse
VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy EBioMedicine, 2019;0(0):. 2019 [PMID: 31130472] (Mouse) Mouse
BVS Valiate, RU Alvarez, L Karra, CM Queiroz-Jú, FA Amaral, F Levi-Schaf, MM Teixeira The immunoreceptor CD300a controls the intensity of inflammation and dysfunction in a model of Ag-induced arthritis in mice J. Leukoc. Biol., 2019;0(0):. 2019 [PMID: 31107994] (Mouse) Mouse
Show All 142 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-17/IL-17A (DY421). (Showing 1 - 3 of 3 FAQs).

  1. I want to stain some T cell subsets (Th17 and Th1), do you have antibodies for that? I need for flow cytometer in sheep or goat.
    • Unfortunately, we have neither a CD4 antibody nor an IL-17 antibody that has been validated in sheep or goat, although if you would like to try one you would again be eligible for our Innovators Reward Program. Please contact us at innovators@novusbio.com with any questions regarding this program.
  2. I'm looking to establish an ELISA for IL-17 and want your recommendation on which antibody pairs to buy. Least expensive ones, please. Also, I'd like the detection antibody to be fluorescently labeled.
    • Thank you for your patience while I reviewed our ELISA validated products for IL17. I was not sure what species you were going to be investigating, so I looked up our data for the human protein. If this is incorrect, just let me know and I can look up products for the species you will be working with. As for antibody pairs, we only had one set that have been tested together: Capture: NBP2-22531 Detection: NBP2-22532. The detection product is only available currently with a biotin conjugate. We can however offer custom conjugation for this product to any of our available conjugates. Please see the following link to see the available fluors: http://www.novusbio.com/support/custom-antibody-labeling.html The typical fee for custom conjugation is usually about $80 additional. Once you know which fluor you would like, I can provide you with a quote. We do also offer several ELISA kits for this target (they typically employ HRP or Biotin detection systems, so I am not sure if they will work for your needs).
  3. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

Biotin DY421
Biotin DY421

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Bioinformatics

Gene Symbol Il17a