FoxP3 Products

FoxP3 Antibody
FoxP3 Antibody
Species: Hu, Rt
Applications: WB, Flow, ICC/IF, IHC-P, PEP-ELISA, Ctrl, ICC/IF
Host: Goat Polyclonal
FoxP3 Overexpression Lysate
FoxP3 Overexpression Lysate
Species: Hu
Applications: WB
FoxP3 Antibody Blocking Pepti ...
FoxP3 Antibody Blocking Peptide
Species: Hu
Applications: AC
FoxP3 Antibody Blocking Pepti ...
FoxP3 Antibody Blocking Peptide
Species: Hu
Applications: AC
Recombinant Human FoxP3 GST ( ...
Recombinant Human FoxP3 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, PA, AP
Support Products


Forkhead box P3 (FoxP3), aka Scurfin and JM2, is a protein involving in immune system responses and functioning as a transcriptional regulator crucial in the development and inhibitory of regulatory T-Cells (Treg). FoxP3 is a master regulator of the Treg lineage, who requires Ahr and STAT-5 and other additional transcription factors to retains its complete function and differentiation. Scurfin remains steady and constitutively expressed in two conditions: a high level in CD25 + CD4 positive regulatory T cells and a low level in CD4 positive/CD25 negative cells. JM2 is absent in CD4 negative/CD8 positive T cells. FoxP3 defects are related to various cancers and autoimmune diseases, and X-linked syndrome (IPEX), while overexpression may also cause severe immunodeficiency.


Entrez Mouse
Uniprot Human
Product By Gene ID 50943
Alternate Names
  • AIID
  • AIIDMGC141961
  • forkhead box P3
  • Forkhead Box Protein P3
  • FOXP3delta7
  • immune dysregulation, polyendocrinopathy, enteropathy, X-linked
  • Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked
  • IPEX
  • JM2
  • MGC141961
  • MGC141963
  • PIDX
  • PIDXMGC141963
  • scurfin
  • Scurfin
  • XPID
  • XPIDpolyendocrinopathy, enteropathy, X-linked

Research Areas for FoxP3

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Biology
Chromatin Research
Transcription Factors and Regulators

Bioinformatics Tool for FoxP3

Discover related pathways, diseases and genes to FoxP3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related FoxP3 Blog Posts

Check out the latest blog posts on FoxP3.
Is has been established that the regulatory transcription factor FOXP3 (a member of the forkhead/winged-helix family of transcription factors) is imperative to immune system homeostasis through CD4+CD25+ regulatory T cell function.  Distinctively, ...    Read more.
Meeting Report: 2nd International Antibody Validation Meeting
Bio-Techne brands Novus Biologicals® and R&D Systems® were proud to support the 2nd International Antibody Validation Meeting held at Bath University, on the 15-16 September, 2016. Almost 100 participants from around the world, including funde...    Read more.
FOXP3: Master Regulatory Transcriptional Factor
FOXP3, a forkhead family transcription factor specially expressed in regulatory T (Treg) cells, controls the expression of many key immune-regulatory genes. Treg cells are a population of T lymphocytes that have critical roles in the immune system hom...    Read more.
FOXP3 is a Master Regulator of T Regulatory (Treg) Cells
FOXP3, a member of forkhead/winged-helix family of transcription factors acts as a "master" regulator for the development and suppressive function of regulatory T cells (Tregs). Its constitutive expression is necessary for the suppressive function of ...    Read more.
Read more FoxP3 related blogs.