||Phosphorylates glucose to produce glucose-6-phosphate and committing it to the glycolytic pathway.
|HSP60 (Heat Shock Protein 60kDa)
||Protein folding and assembly of imported polypeptide.
|HSP70 (Heat Shock Protein 70kDa)
||Role in protein folding, degradation, and association with presequence translocase-associated motor (PAM) to drive preprotein import.
||Inner membrane / Cristae
||One of most abundant mitochondrial proteins. Role in maintenance of cristae morphology.
||Show antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.
||Subunit of the translocase of inner membrane 23 (TIM23) complex that functions to transport peptide-contain proteins across the inner membrane.
||Together with TOM22 functions as the transit peptide receptor and facilitates the movement of preproteins into the TOM40 translocation pore.
||Voltage dependent anion channel (VDAC) pore that allows entry and exit between the cytosol and mitochondria. Critical substrate for PINK/Parkin-mediated autophagy.
*Note: This table is not an inclusive list of all mitochondrial proteins involved in oxidative phosphorylation.
||Confocal immunofluorescent analysis of HeLa cells staining with Rabbit Anti-Hsp60 Polyclonal antibody (NBP1-77397) at 1:100 followed by Alexa Fluor 488-conjugated Goat to rabbit IgG secondary antibody (green). Actin filaments were labeled with Alexa Fluor 568 phalloidin (red) and nuclei were stained with DAPI (blue).
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