Mitofusin 1 Products

Antibodies
Lysates
Mitofusin 1 Overexpression Ly ...
Mitofusin 1 Overexpression Lysate ...
NBL1-13039
Applications: WB
Proteins
Recombinant Human Mitofusin 1 ...
Recombinant Human Mitofusin 1 Protein
H00055669-P01
Species: Hu
Applications: WB, ELISA, Func, PA
Mitofusin 1 Recombinant Prote ...
Mitofusin 1 Recombinant Protein An...
NBP2-57125PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human Mitofusin 1 ...
Recombinant Human Mitofusin 1 Protein
H00055669-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Mitofusin 1 RNAi
Mitofusin 1 RNAi
H00055669-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Mitofusin 1 RNAi
Mitofusin 1 RNAi
H00055669-R02
Species: Hu
Applications: RNAi, RNAi SP
Mitofusin 1 RNAi
Mitofusin 1 RNAi
H00055669-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

MFN1 (Mitofusin-1) is a nuclear encoded mitochondrial membrane protein that mediates mitochondrial fusion and morphology in mammalian cells. MFN1 and MFN2 are homologs of the Drosophila protein Fuzzy Onion (Fzo) that interact with each other to facilitate mitochondrial targeting. MFN1 is ubiquitously expressed,with slightly higher leves detectedl in kidney and heart. MFN2 may be overexpressed in some tumors, such as lung cancers.

Mitochondrial fusion occurs in many cell types and is a fundamental component of mitochondria morphology, which is balanced between fusion and fission. Mitochondrial dysfunction is a major cause of neuronal death in degenerative disorders, such as Parkinson's disease, and can be triggered by an imbalance in the dynamic equilibrium between mitochondrial fission and fusion.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 55669
Alternate Names
  • EC 3.6.5
  • EC 3.6.5.-
  • putative transmembrane GTPase
  • MGC41806
  • mitofusin-1
  • DKFZp762F247
  • mitochondrial transmembrane GTPase FZO-2
  • Transmembrane GTPase MFN1
  • mitochondrial transmembrane GTPase Fzo-1
  • Fzo homolog
  • hfzo2
  • FLJ20693
  • hfzo1
  • mitofusin 1

Research Areas for Mitofusin 1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Biology
Cellular Markers
Mitochondrial Fusion Proteins
Mitochondrial Markers
Neurodegeneration
Neuroscience
Signal Transduction

PTMs for Mitofusin 1

Learn more about PTMs related to Mitofusin 1.

Phosphorylation
Ubiquitination
Oxidation
Cleavage
Sumoylation

Bioinformatics Tool for Mitofusin 1

Discover related pathways, diseases and genes to Mitofusin 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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