AIF Products

Antibodies
AIF Antibody
AIF Antibody
Species: Hu, Mu, Rt
Applications: WB, Simple Western, ICC
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
AIF Antibody
AIF Antibody
NBP2-27177
Species: Hu, Mu, Rt, Bv, Ca
Applications: WB, Simple Western, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
AIF Antibody (4E7)
AIF Antibody (4E7)
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
Antibody Pairs
AIF Antibody Pair
AIF Antibody Pair
H00009131-AP21
Species: Hu
Applications: S-ELISA
Lysates
AIF Overexpression Lysate (De ...
AIF Overexpression Lysate (Denatured)
H00009131-T01
Species: Hu
Applications: WB
Proteins
AIF Recombinant Protein
AIF Recombinant Protein
H00009131-P01
Species: Hu
Applications: WB, ELISA, PA
AIF Recombinant Protein
AIF Recombinant Protein
NBP2-51612
Species: Hu
Applications: PAGE
AIF Blocking Peptide
AIF Blocking Peptide
NBP1-76838PEP
Species: Hu
Applications: AC
RNAi
AIF RNAi
AIF RNAi
H00009131-R03
Species: Hu
AIF RNAi
AIF RNAi
H00009131-R01
Species: Hu
AIF RNAi
AIF RNAi
H00009131-R02
Species: Hu

Description

AIF, or apoptosis-inducing factor, is a flavoprotein localized to the mitochondrial membrane that plays a primary role in caspase-independent cell death, or apoptosis (1,2). AIF translocates to the nucleus when apoptosis is induced and causes mitochondria to release the apoptogenic proteins, cytochrome c and caspase-9. Apoptotic activity of AIF leads to chromatin condensation and DNA fragmentation (1). Similar to cytochrome c, AIF is a bifunctional protein with an oxidoreductase function and a second apoptogenic function. In contrast to cytochrome c, however, AIF acts in a caspase-independent fashion (2,3,4).

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9131
Alternate Names
  • Programmed cell death protein 8
  • COXPD6
  • programmed cell death 8 (apoptosis-inducing factor)
  • PDCD8striatal apoptosis-inducing factor
  • AIFapoptosis-inducing factor 1, mitochondrial
  • MGC111425
  • apoptosis-inducing factor, mitochondrion-associated, 1

Research Areas for AIF

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Biology
Cell Cycle and Replication
Chromatin Research
Mitochondrial Markers
Tumor Suppressors

Bioinformatics Tool for AIF

Discover related pathways, diseases and genes to AIF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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