TTC11 Antibody


Western Blot: TTC11 Antibody [NB100-56646] - Effect of liraglutide on brain cortical mitochondrial fission/fusion markers in female mice with early AD-like pathology. Brain cortical Fis1 (A) protein levels were more
Immunohistochemistry-Paraffin: TTC11 Antibody [NB100-56646] - Analysis of methcarn-fixed, paraffin-embedded hippocampus from control (normal) and Alzheimer brain. Quantification in five AD brains and five age-matched more
Knockdown Validated: TTC11 Antibody [NB100-56646] - Analysis of Fis1 in A) human HeLa and B) mouse NIH 3T3 lysate using Fis1 antibody at 1:1000 dilution. B. Specificity validation of the Fis1 antibody. Fis1 was analyzed more

Product Details

Product Discontinued
View other related TTC11 Primary Antibodies

Order Details

    • Catalog Number
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

TTC11 Antibody Summary

Amino acids 11-25 of human Fis1 protein were used as the immunogen.
Predicted Species
Canine (93%). Backed by our 100% Guarantee.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • ELISA reported in scientific literature (PMID 27494529)
  • Immunocytochemistry/Immunofluorescence reported in scientific literature (PMID 34999205)
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:100. Use reported in scientific literature (Wang et al (2009))
  • Knockdown Validated
  • Western Blot 1:500 - 1:1000
NIH 3T3 Whole Cell Lysate
TTC11 Overexpression Lysate
HeLa Whole Cell Lysate
Read Publications using
NB100-56646 in the following applications:

Reactivity Notes

Predicted to react with Chimpanzee (66%), Canine (93%). Rat and mouse reactivity reported in scientific literature.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Whole antisera with PBS and 0.05% BSA
0.05% Sodium Azide

Alternate Names for TTC11 Antibody

  • CGI-135
  • FIS1 homolog
  • Fis1
  • fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
  • fission 1 (mitochondrial outer membrane) homolog (yeast)
  • H_NH0132A01.6
  • hFis1
  • mitochondrial fission 1 protein
  • tetratricopeptide repeat domain 11
  • Tetratricopeptide repeat protein 11
  • TTC11TPR repeat protein 11


TTC11 is a 17KDa integral membrane protein, and is a novel member of the mitochondrial fission machinery. It consists of a central leucine-zipper domain, a coiled-coil region, a tetratricopeptide repeat domain and a C-terminal transmembrane domain. It is a human orthologue of Fis1p (S.cerevisiae) and is localized in the outer mitochondrial membrane. Fis1 acts as a pro-apoptotic factor and plays a vital role in the regulation of mitochondrial fission. It interacts with DLP1 and Mdv1p and facilitates Dnm1p recruitment to the functional fission complex, thereby inducing apoptosis. Role of Fis1 has also been implicated in growth and division of peroxisomes. Loss of Fis1 inhibits apoptosis and results in elongation of mammalian mitochondria.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Fi, Hu, Mu, Pm, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, IP, Simple Western, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Species: Ca, Hu, Pm, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, IP, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Rt
Applications: ELISA, IHC, IHC-P, RNAi, WB
Species: Hu, Mu, Rt
Applications: ELISA, Flow, ICC/IF, IP, KD, WB
Species: Ch, Hu, Mu, Po, Rt, Ze
Applications: IB, ICC/IF, IHC, IHC-P, Simple Western, WB
Species: Hu, Mu, Pm
Applications: ChIP, IHC, IHC-P, IP, WB
Species: Hu, Mu
Applications: ELISA, Flow, IHC, IHC-Fr, IHC-P, IP, KO, Simple Western, WB
Species: Hu, Pm, Mu, Pm, Rt
Applications: Flow, IHC, IHC-P, WB
Species: Dr, Hu, Mu, Rb, Rt
Applications: Flow-CS, Flow-IC, Flow, IB, ICC/IF, IHC, IHC-P, Simple Western, WB
Species: Hu
Applications: ELISA, AP, PA, WB
Species: Hu
Applications: ICC, IHC, WB
Species: Hu, Rt
Applications: IHC, IHC-P, WB
Species: Ca, Hu, Mu, Rt
Applications: IHC, IHC-Fr, IHC-P, IP, WB
Species: Hu
Applications: ICC/IF, IP, KD, WB
Species: Bv, Hu, Pm, Mu, Po, Rt
Applications: Func, IHC, IHC-Fr, IHC-P, WB
Species: Fi, Hu, Mu, Rt
Applications: ELISA, IHC, KD, Simple Western, WB
Species: Hu, Mu, Rt, Ca
Applications: WB, ELISA, ICC/IF, IHC, KD
Supplier Logo

Publications for TTC11 Antibody (NB100-56646)(31)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 6 applications: ELISA, ICC/IF, IF/IHC, IHC, IHC-P, WB.

Filter By Application
All Applications
Filter By Species
All Species
Showing Publications 1 - 10 of 31. Show All 31 Publications.
Publications using NB100-56646 Applications Species
Vijayan M, Reddy PH Reduced VDAC1, Maintained Mitochondrial Dynamics and Enhanced Mitochondrial Biogenesis in a Transgenic Tau Mouse Model of Alzheimer's Disease International journal of molecular sciences 2022-08-02 [PMID: 35955694] (WB, IF/IHC, Mouse)

WB dilution used 1:1000, IHC dilution used 1:102
WB, IF/IHC Mouse
Wongkitikamjorn W, Hosomichi J, Wada E et al. Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats Cureus 2022-05-17 [PMID: 35600069] (IHC, WB) IHC, WB
Wang X, Tang Y, Xie N et al. Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1/p53/Drp1 signaling Journal of ethnopharmacology 2022-04-16 [PMID: 35439546] (WB, Mouse) WB Mouse
Lim S, Deaver JW, Rosa-Caldwell ME et al. Muscle miR-16 deletion results in impaired insulin sensitivity and contractile function in a sex-dependent manner American journal of physiology. Endocrinology and metabolism 2022-01-24 [PMID: 35068192]
Aloysius Dhivya M, Sulochana K, Devi S High glucose induced inflammation is inhibited by copper chelation via rescuing mitochondrial fusion protein 2 in retinal pigment epithelial cells Cellular Signalling 2022-01-01 [PMID: 34999205] (ICC/IF, Human) ICC/IF Human
Awasthi S, Hindle A, Sawant NA Et al. RALBP1 in Oxidative Stress and Mitochondrial Dysfunction in Alzheimer's Disease Cells 2021-11-10 [PMID: 34831336]
Lim S, Deaver JW, Rosa-Caldwell ME Et al. Development of metabolic and contractile alterations in development of cancer cachexia in female tumor-bearing mice Journal of applied physiology (Bethesda, Md. : 1985) 2021-11-11 [PMID: 34762526]
Ramya R, Bharathidevi SR Paraoxonase 2 protects against the CML mediated mitochondrial dysfunction through modulating JNK pathway in human retinal cells Biochimica et biophysica acta. General subjects 2021-10-25 [PMID: 34710487] (ICC/IF, WB, Human) ICC/IF, WB Human
Rosa-Caldwell ME, Lim S, Haynie WS Et al. Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice Journal of cachexia, sarcopenia and muscle 2021-09-29 [PMID: 34585846] (WB, Mouse) WB Mouse
Fernandes T, Resende R, Silva D Et Al. Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer s Disease Biomedicines 2021-07-24 [PMID: 34440085] (WB) WB
Show All 31 Publications.

Reviews for TTC11 Antibody (NB100-56646) (0)

There are no reviews for TTC11 Antibody (NB100-56646). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TTC11 Antibody (NB100-56646) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies


Isotype Controls

Additional TTC11 Products

Bioinformatics Tool for TTC11 Antibody (NB100-56646)

Discover related pathways, diseases and genes to TTC11 Antibody (NB100-56646). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TTC11 Antibody (NB100-56646)

Discover more about diseases related to TTC11 Antibody (NB100-56646).

Pathways for TTC11 Antibody (NB100-56646)

View related products by pathway.

PTMs for TTC11 Antibody (NB100-56646)

Learn more about PTMs related to TTC11 Antibody (NB100-56646).

Research Areas for TTC11 Antibody (NB100-56646)

Find related products by research area.

Blogs on TTC11

There are no specific blogs for TTC11, but you can read our latest blog posts.
mFlour Violet Conjugated Antibodies

Contact Information

Product PDFs


Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.


Review this Product

Be the first to review our TTC11 Antibody and receive a gift card or discount.


Gene Symbol FIS1