OPA1 Products

Antibodies
OPA1 Antibody
OPA1 Antibody
NB110-55290
Species: Hu, Mu, Rt, Po, Ch, Primate, Zebrafish
Applications: WB, Simple Western, IHC, IHC-P
Host: Rabbit Polyclonal
OPA1 Antibody (1E8-1D9)
OPA1 Antibody (1E8-1D9)
NBP1-71656
Species: Hu, Mu, Rt, Bv, ChHa
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
OPA1 Antibody
OPA1 Antibody
NBP2-34206
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
OPA1 Overexpression Lysate (N ...
OPA1 Overexpression Lysate (Native)
NBP2-05728
Applications: WB
OPA1 Overexpression Lysate (N ...
OPA1 Overexpression Lysate (Native)
NBP2-05725
Applications: WB
OPA1 Overexpression Lysate (N ...
OPA1 Overexpression Lysate (Native)
NBP2-05723
Applications: WB
Proteins
OPA1 Peptide
OPA1 Peptide
NB110-55290PEP
Species: Hu
OPA1 Recombinant Protein
OPA1 Recombinant Protein
H00004976-P01
Species: Hu
Applications: WB, ELISA, Func, PA
OPA1 Partial Recombinant Prot ...
OPA1 Partial Recombinant Protein
H00004976-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
OPA1 RNAi
OPA1 RNAi
H00004976-R16
Species: Hu
Applications: RNAi, RNAi SP
OPA1 RNAi
OPA1 RNAi
H00004976-R09
Species: Hu
Applications: RNAi, RNAi SP
OPA1 RNAi
OPA1 RNAi
H00004976-R14
Species: Hu
Applications: RNAi, RNAi SP

Description

OPA1 product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Highly expressed in the retina, OPA1 mutations have been associated with a dominantly inherited optic neuropathy, called optic atrophy type 1, resulting in progressive loss of visual acuity. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene.

OPA1 antibodies are used primarily for vision research.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Mouse
Rat
Product By Gene ID 4976
Alternate Names
  • MGM1
  • mitochondrial dynamin-like GTPase
  • FLJ12460
  • NTGmitochondrial dynamin-like 120 kDa protein
  • NPGlargeG
  • KIAA0567dynamin-like 120 kDa protein, mitochondrial
  • Optic atrophy protein 1
  • optic atrophy 1 (autosomal dominant)

Research Areas for OPA1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Mitochondrial Fusion Proteins
Neurodegeneration
Neuroscience
Sensory Systems
Vision

PTMs for OPA1

Learn more about PTMs related to OPA1.

Phosphorylation
Cleavage
Ubiquitination
Sumoylation
Nitrosylation
Acetylation

Bioinformatics Tool for OPA1

Discover related pathways, diseases and genes to OPA1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related OPA1 Blog Posts

Check out the latest blog posts on OPA1.
BNIP3 - a regulator of mitochondrial autophagy and cell death
Bcl-2 nineteen-kilodalton interacting protein 3 (BNIP3) is a pro-apoptotic BH3-only protein. BNIP3 localizes to the mitochondrial membrane where it plays a key role in mitochondrial autophagy and cell death pathways. Similar to other Bcl-2 family m...    Read more.
Understanding OPA1 and Mitochondrial Function
OPA1 belongs to the Dynamin large GTPase protein family. OPA1 exists as a single-pass membrane protein localized in the mitochondrial inner membrane and also as a soluble form in the mitochondrial intermembrane space. There, it is a key player in fusi...    Read more.
Read more OPA1 related blogs.