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Androgen R/NR3C4 Antibody (H7507)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clone
H7507
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Suitable Sample Type
23015

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Androgen R/NR3C4 Antibody (H7507) Summary

Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
AR
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Applications/Dilutions

Dilutions
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
Reviewed Applications
Read 1 Review rated 4
using
PP-H7507-00 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
A liquid formulation in physiologic saline with 0.1% NaN3.
Preservative
0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Androgen R/NR3C4 Antibody (H7507)

  • AIS
  • Androgen R
  • androgen receptor
  • AndrogenR
  • AR
  • DHTR
  • DHTRTFM
  • Dihydrotestosterone receptorHYSP1
  • HUMARA
  • NR3C4
  • NR3C4KD
  • Nuclear receptor subfamily 3 group C member 4
  • SBMA
  • SMAX1
  • SMAX1SBMA
  • spinal and bulbar muscular atrophy

Background

Human Androgen Receptor (AR; NR3C4) is a 110 kDa member of the NR3 subfamily of the nuclear hormone receptor family. Androgen receptors are expressed by androgen-sensitive tissue (bone, prostate, testis) and exist as both ahomodimers and a heterodime in a complex with the glucocorticoid receptor. Multiple forms of the androgen receptor are known to exist. The 110 kDa 'B' form is 919 amino acids in length. Phosphorylation increases its molecular weight to 112 kDa and 114 kDa. A five amino acid deletion (amino acids 74 - 78) in AR-B has been reported. In addition, a short 'A' form of 87 kDa and 732 amino acids is also known. Expanded polyglutamine repeats in the androgen receptor are known to cause Kennedy's disease, an X-linked form of motor neuron disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Review for Androgen R/NR3C4 Antibody (PP-H7507-00) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using PP-H7507-00:
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Images Ratings Applications Species Date Details
  4
reviewed by:
Verified Customer
 WB Human 02/25/2015
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Summary

ApplicationWestern Blot
Sample TestedSee PMID 19152342
SpeciesHuman

Blocking

Blocking DetailsSee PMID 19152342

Details

Detection NotesSee PMID 19152342

Comments

CommentsIndependent review from antibodyresource.comPublished in PMID 19152342.

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Recent Reviews

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 Verified Customer
02/25/2015
Application: WB
Species: Human
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Bioinformatics

Gene Symbol AR