TMEM37 Antibody

Immunocytochemistry/Immunofluorescence: TMEM37 Antibody [NBP2-47602] - Immunofluorescent staining of human cell line Hep G2 shows localization to nucleus, nucleoli fibrillar center & cytosol.

Immunohistochemistry-Paraffin: TMEM37 Antibody [NBP2-47602] - Staining in human kidney and pancreas tissues using anti-TMEM37 antibody. Corresponding TMEM37 RNA-seq data are presented for the same tissues.

Immunohistochemistry-Paraffin: TMEM37 Antibody [NBP2-47602] - Staining of human kidney shows high expression.

Immunohistochemistry-Paraffin: TMEM37 Antibody [NBP2-47602] - Staining of human pancreas shows low expression as expected.

• Reactivity: Hu
• Applications: ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

TMEM37 Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: LMVSQLCEDKHSQCKWVMGS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TMEM37
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  TMEM37 Protein (NBP2-47602PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for TMEM37 Antibody

• Neuronal voltage-gated calcium channel gamma-like subunit
• transmembrane protein 37PRPR1
• voltage-dependent calcium channel gamma subunit-like protein
• voltage-dependent calcium channel gamma-like subunit

Background

The TMEM37 gene codes for a 190 amino acid long, 20 kDA transmembrane protein that is thought to stabilize the calcium channel in an inactivated state and monitors calcium current when coexpressed with CACNA1G. The TMEM37 gene is associated with food allergies, leukemia, and neuronitis and has been known to interact with genes HBP1, MPP3, ORM1, TNFRSF14, and TNFRSF11A. It plays a role in the MAPK signaling pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TMEM37