Post-translational modifications (PTMs) take many forms; some PTMs involve the attachment of functional groups to amino acid residues, while other PTMs involve the cleavage of parts of proteins, or even the degradation of the entire protein itself. Protein cleavage is critical for cellular functions such as apoptosis, signaling and cell-cell interaction. Post-translational protein cleavage, also known as proteolysis, is carried out by enzymes called proteases. Each protease cleaves a protein's peptide bonds at a specific cleavage site, and proteases are classified based on the residue on which they take action.
Cleavage Bioinformatics Tool
Laverne is a handy bioinformatics tool to help facilitate scientific exploration of related genes, diseases and pathways based on co-citations. Explore more on Cleavage below!
For more information on how to use Laverne, please read the How to Guide.
We have 2700 products for the study of Cleavage that can be applied to Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Chromatin Immunoprecipitation (ChIP), Immunohistochemistry from our catalog of antibodies and ELISA kits.