Androgen R/NR3C4 Products

Antibodies
Androgen R/NR3C4 Antibody
Androgen R/NR3C4 Antibody
NBP2-15384
Species: Hu, Mu, Bovine, Canine, Chicken, Porcine, Rabbit, Rat, Sheep, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Androgen R/NR3C4 Overexpressi ...
Androgen R/NR3C4 Overexpression Ly...
NBP2-04146
Applications: WB
Androgen R/NR3C4 Overexpressi ...
Androgen R/NR3C4 Overexpression Ly...
NBL1-07644
Applications: WB
Proteins
Androgen R/NR3C4 Partial Reco ...
Androgen R/NR3C4 Partial Recombina...
H00000367-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Androgen R/NR3C4 RNAi
Androgen R/NR3C4 RNAi
H00000367-R01
Species: Hu
Androgen R/NR3C4 RNAi
Androgen R/NR3C4 RNAi
H00000367-R02
Species: Hu

Description

Androgens have a broad range of effects on the appearance and maintenance of male secondary sexual characteristics. Like other members of the steroid superfamily, the androgen receptor (AR) consists of an amino terminal modulating domain, a central DNA binding domain, a hinge region and a carboxy terminal ligand binding domain. The androgen receptor (AR) is a 110 kDa androgen-dependent transcription factor that is a member of the steroid/nuclear receptor gene superfamily. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease and male infertility. The PI3K/Akt signaling pathway plays an important role in regulating AR activity through phosphorylation of AR at Ser213/210 and Ser791/790. Growth factors or cytokines may induce phosphorylation of AR through the PI3K/Akt pathway. Activation of the PI3K/AKt pathway is thought to have a survival role in prostate cancer by protecting cells from apoptosis.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 367
Alternate Names
  • HUMARA
  • spinal and bulbar muscular atrophy
  • AIS
  • DHTRTFM
  • SMAX1SBMA
  • NR3C4KD
  • Dihydrotestosterone receptorHYSP1
  • Nuclear receptor subfamily 3 group C member 4
  • androgen receptor

Research Areas for Androgen R/NR3C4

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Cellular Markers
Phospho-Specific

Bioinformatics Tool for Androgen R/NR3C4

Discover related pathways, diseases and genes to Androgen R/NR3C4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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