CD31/PECAM-1 Antibody [PE]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications Flow
Please see the vial label for concentration. If unlisted please contact technical services.

CD31/PECAM-1 Antibody [PE] Summary

A genomic peptide made to an internal region of human CD31/PECAM1 (within residues 100-300). [Swiss-Prot P16284]
Membrane; Single-pass type I membrane protein. Cell junction. Note: Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
PE (A=488, E=575)
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Immunogen affinity purified


Application Notes
This CD31/PECAM1 antibody is useful for Immunohistochemistry, Flow Cytometry, and Western Blot, where a band is seen ~ 150 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human and mouse.

Alternate Names for CD31/PECAM-1 Antibody [PE]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • endoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule


CD31/PECAM1 (cluster of differentiation 31/platelet-endothelial cell adhesion molecule-1), is a transmembrane glycoprotein belonging to immunoglobulin (Ig)-superfamily of cell adhesion molecules and is expressed by platelets, megakaryocytes, endothelial cells, certain T cells etc., and has been shown to modulate cell adhesion, endothelial cell migration and angiogenesis. CD31/PECAM-1 undergoes phosphorylation at Tyr686 through SRC family members upon versatile stimuli that includes mechanical stress and oxidative stress also, and this phosphorylation facilitates its associations with a number of SH2 domain containing binding partners such as PI3K, SHIP, PLC gamma and SHP-2. Besides, exhibiting adhesive properties, CD31/PECAM-1 implicates in angiogenesis, platelet function, and thrombosis, mechanosensing of endothelial cell response to fluid shear stress, and control of multiple stages of leukocyte migration through venular walls. Importantly, CD31/PECAM-1 is the most commonly used pan-endothelial marker for blood vessels and due to its involvement in angiogenesis and vascular permeability, it plays important role in the growth as well as metastatic spread of several cancers.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies


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Contact Information

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Gene Symbol PECAM1

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