Angiogenesis is an essential process during normal tissue growth and in response to wound healing. It is vital for the development of new connective tissue and small blood vessels from pre-existing vessels. Additionally, due to the mechanisms of angiogenesis, it is also a major step in the transition and proliferation of malignant tumors from benign states.

Since angiogenesis is such an essential player in tumor progression, many inhibitors have been developed to several proteins in order to impede the growth of new blood vessels. Many of these proteins are pro-angiogenic growth factors, which are responsible for inducing blood vessel development. Some commonly studied stimulators for angiogenesis include fibroblast growth factor (FGF), vascular endothelial growth factor (VEGF), and transforming growth factor-β (TGF-β), which are involved in the proliferation and differentiation of endothelial cells.

FGF21 Antibody

 VEGF Antibody (VG1)

TGF beta 1 Antibody (7F6)