Integrin alpha V beta 3 Products

Antibodies
Integrin alpha V beta 3 Antib ...
Integrin alpha V beta 3 Antibody (...
MAB3050
Species: Hu
Applications: Flow, IHC, IP, AdBlk
Host: Mouse Monoclonal
Integrin alpha V beta 3 Antib ...
Integrin alpha V beta 3 Antibody (...
NBP2-29719
Species: Hu
Applications: Func, IHC, IHC-Fr, IP, IHC-P (-)
Host: Mouse Monoclonal

Description

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha V beta 3 is the predominant integrin of osteoclasts (bone resorbing cells) and is upregulated in malignant melanoma. Integrin alpha V beta 3 binds to a range of ECM proteins (e.g. vitronectin, fibrinogen, fibronectin) via an Arg-Gly-Asp (RGD) motif.

Bioinformatics

Entrez Human
Product By Gene ID 3685
Alternate Names
  • Vitronectin receptor subunit alpha
  • CD51 antigen
  • antigen identified by monoclonal L230
  • integrin alpha-V
  • CD51
  • VNRADKFZp686A08142
  • MSK8
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

Research Areas for Integrin alpha V beta 3

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cytoskeleton Markers
Extracellular Matrix
Signal Transduction

PTMs for Integrin alpha V beta 3

Learn more about PTMs related to Integrin alpha V beta 3.

Phosphorylation

Bioinformatics Tool for Integrin alpha V beta 3

Discover related pathways, diseases and genes to Integrin alpha V beta 3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Integrin alpha V beta 3 Blog Posts

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Integrin alpha v beta 3 - a target for inhibiting tumor angiogenesis
Integrins are a family of transmembrane proteins involved in diverse processes including cell adhesion, signal transduction, cell migration, and differentiation. They exist as heterodimers consisting of noncovalently linked alpha and beta subunits....    Read more.
Read more Integrin alpha V beta 3 related blogs.