TLR6 Antibody - BSA Free

Western Blot: TLR6 Antibody [NBP1-76664] - Jurkat cell lysate with TLR6 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunocytochemistry/ Immunofluorescence: TLR6 Antibody - BSA Free [NBP1-76664] - Immunocytochemistry of TLR6 in Jurkat cells with TLR6 antibody at 2 ug/mL.

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TLR6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit TLR6 Antibody - BSA Free (NBP1-76664) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: TLR6 antibody was raised against a peptide corresponding to 13 amino acids near the center of human TLR6. The immunogen is located within amino acids 390 - 440 of TLR6.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TLR6
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 0.5-2 ug/ml
• Agonist:
  • MALP-2, TLR6 and TLR2 ligand NBP2-26219
• Control Peptide:

  TLR6 Peptide (NBP1-76664PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for TLR6 Antibody - BSA Free

• CD286 antigen
• CD286
• TLR6
• toll-like receptor 6

Background

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TLR6
• Uniprot:
  • NP_006059(Human)