Human CCL2/MCP-1 Quantikine ELISA Kit Summary
The Quantikine Human MCP-1 Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MCP-1
in cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant human MCP-1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant human MCP-1. Results obtained using natural human ... MCP-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MCP-1.
Natural and recombinant human MCP-1
Solid Phase Sandwich ELISA
No significant interference observed with available related molecules.
Packaging, Storage & Formulations
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human CCL2/MCP-1 Quantikine ELISA Kit
C-C motif chemokine ligand 2 CCL2 GDCF-2 HC11 HSMCR30 MCAF Mcp1 MCP-1 SCYA2 SMC-CF Background
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
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Applications: WB, Simple Western, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Species: Hu, Rt, Rb
Applications: WB, Flow, IHC, IHC-P, KO
Applications: WB, Flow, CyTOF-ready
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
Publications for CCL2/JE/MCP-1 (DCP00)(184)
We have publications tested in 5 confirmed species: Human, Rat, Porcine, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Primate - Macaca mulatta (Rhesus Macaque).
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Publications using DCP00
PM Witschen, TS Chaffee, NJ Brady, DN Huggins, TP Knutson, RS LaRue, SA Munro, L Tiegs, JB McCarthy, AC Nelson, KL Schwertfeg Tumor Cell Associated Hyaluronan-CD44 Signaling Promotes Pro-Tumor Inflammation in Breast Cancer Cancers (Basel), 2020;12(5):. 2020 [PMID: 32455980] (Human)
M Sugiyama, Y Wada, N Kanazawa, S Tachibana, T Suzuki, K Matsumoto, M Iyoda, H Honda, T Shibata A cross-sectional analysis of clinicopathologic similarities and differences between Henoch-Schï¿½nlein purpura nephritis and IgA nephropathy PLoS ONE, 2020;15(4):e0232194. 2020 [PMID: 32324811] (Human)
A Lorenzo-Al, A Pello, Á Aceña, J Martínez-M, Ó González-L, N Tarín, C Cristóbal, LM Blanco-Col, JL Martín-Ven, A Huelmos, C Gutiérrez-, M López-Cast, A Kallmeyer, E Cánovas, J Alonso, LL Bescós, J Egido, Ó Lorenzo, J Tuñón Galectin-3 Is Associated with Cardiovascular Events in Post-Acute Coronary Syndrome Patients with Type-2 Diabetes J Clin Med, 2020;9(4):. 2020 [PMID: 32294902] (Human)
X Wang, G Bhutani, LE Vaughan, FT Enders, Z Haskic, D Milliner, JC Lieske, Urinary monocyte chemoattractant protein 1 associated with calcium oxalate crystallization in patients with primary hyperoxaluria BMC Nephrol, 2020;21(1):133. 2020 [PMID: 32293313] (Human)
S Ma, T Tominaga, K Kanda, K Sugama, C Omae, S Hashimoto, K Aoyama, Y Yoshikai, K Suzuki Effects of an 8-Week Protein Supplementation Regimen with Hyperimmunized Cow Milk on Exercise-Induced Organ Damage and Inflammation in Male Runners: A Randomized, Placebo Controlled, Cross-Over Study Biomedicines, 2020;8(3):. 2020 [PMID: 32143279] (Human)
YY Liu, SY Wang, YN Li, WJ Bian, LQ Zhang, YH Li, L Long, X Liu, XW Zhang, ZG Li Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA Chin. Med. J., 2020;0(6):679-686. 2020 [PMID: 32068606] (Human)
IV Kravchenko, VA Furalyov, VO Popov Glycated albumin stimulates expression of inflammatory cytokines in muscle cells Cytokine, 2020;128(0):154991. 2020 [PMID: 32000013] (Human)
Y He, Q Yang, X Wang, A Jia, W Xie, J Zhou Inhibition of Triggering Receptor Expressed on Myeloid Cell-1 Alleviates Acute Gouty Inflammation Mediators Inflamm., 2019;2019(0):5647074. 2019 [PMID: 31885496] (Human)
S Del Turco, L Quattrini, R Colucci, M Gaggini, C La Motta, G Basta A 2,3-diphenylpyrido[1,2-a] pyrimidin-4-one derivative inhibits specific angiogenic factors induced by TNF-alpha Saudi Pharm J, 2019;27(8):1174-1181. 2019 [PMID: 31885477] (Human)
T Kishimoto, N Fujimoto, T Ebara, T Omori, T Oguri, A Niimi, T Yokoyama, M Kato, I Usami, M Nishio, K Yoshikawa, T Tokuyama, M Tamura, Y Yokoyama, K Tsuboi, Y Matsuo, J Xu, S Takahashi, M Abdelgied, WT Alexander, DB Alexander, H Tsuda Serum levels of the chemokine CCL2 are elevated in malignant pleural mesothelioma patients BMC Cancer, 2019;19(1):1204. 2019 [PMID: 31823764] (Human)
Show All 184 Publications.
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Product General Protocols
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FAQs for CCL2/JE/MCP-1 (DCP00). (Showing 1 -
1 of 1 FAQs).
wondering what the difference is between your quantikine and duo set elisas?
Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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Bioinformatics Tool for CCL2/JE/MCP-1 (DCP00)
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