Human CCL2/MCP-1 Quantikine ELISA Kit

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

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Catalog# & Conjugate Size Price

Human CCL2/MCP-1 Quantikine ELISA Kit Summary

Background
The Quantikine Human MCP-1 Immunoassay is a 3.5 or 4.5 hour solid phase ELISA designed to measure MCP-1 in cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant human MCP-1 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate recombinant human MCP-1. Results obtained using natural human ...MCP-1 showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human MCP-1.
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Specificity
Natural and recombinant human MCP-1
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
CCL2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DCP00.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human CCL2/MCP-1 Quantikine ELISA Kit

  • C-C motif chemokine ligand 2
  • CCL2
  • GDCF-2
  • HC11
  • HSMCR30
  • MCAF
  • Mcp1
  • MCP-1
  • SCYA2
  • SMC-CF

Background

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Publications for CCL2/JE/MCP-1 (DCP00)(200)

We have publications tested in 5 confirmed species: Human, Rat, Porcine, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque), Primate - Macaca mulatta (Rhesus Macaque).


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Human
(183)
Rat
(2)
Porcine
(3)
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
(2)
Primate - Macaca mulatta (Rhesus Macaque)
(8)
All Species
Showing Publications 1 - 10 of 200. Show All 200 Publications.
Publications using DCP00 Applications Species
B Sadeghi, E Roshandel, A Pirsalehi, S Kazemi, G Sankanian, M Majidi, M Salimi, N Aghdami, H Sadrosadat, S Samadi Koc, F Alaeddini, O Ringden, A Hajifathal Conquering the cytokine storm in COVID-19-induced ARDS using placenta-derived decidua stromal cells Journal of Cellular and Molecular Medicine, 2021;0(0):. 2021 [PMID: 34632708] (Human) Human
C Yamashiro, K Tokuda, Y Kobayashi, F Higashijim, T Yoshimoto, M Ota, T Ogata, A Ashimori, M Kobayashi, M Hatano, SH Uchi, M Wakuta, S Teranishi, K Kimura Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon's capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-10 Scientific Reports, 2021;11(1):16096. 2021 [PMID: 34373467] (Human) Human
EM Cody, MR Bennett, G Gulati, Q Ma, M Altaye, P Devarajan, HI Brunner Successful Urine Multiplex Bead Assay to Measure Lupus Nephritis Activity Kidney international reports, 2021;6(7):1949-1960. 2021 [PMID: 34307989] (Human) Human
P Janssens, JP Decuypere, S De Rechter, L Breysem, D Van Giel, J Billen, A Hindryckx, L De Catte, M Baldewijns, KBM Claes, KM Wissing, K Devriendt, B Bammens, I Meyts, VE Torres, R Vennekens, D Mekahli Enhanced MCP-1 Release in Early Autosomal Dominant Polycystic Kidney Disease Kidney international reports, 2021;6(6):1687-1698. 2021 [PMID: 34169210] (Human) Human
D Nieri, T Neri, G Barbieri, S Moneta, G Morelli, D Mingardi, S Spinelli, L Ghiadoni, M Falcone, G Tiseo, F Menichetti, M Franzini, L Caponi, A Paolicchi, R Pancani, F Pistelli, L Carrozzi, A Celi, Pisa COVID C-C motive chemokine ligand 2 and thromboinflammation in COVID-19-associated pneumonia: A retrospective study Thrombosis Research, 2021;204(0):88-94. 2021 [PMID: 34153649] (Human) Human
L Avila, ML Neves, AR Abreu, CR Fiuza, L Fukusawa, N Meziat-Fil, AR Soares San Cognitive functional therapy (CFT) compared with core training exercise (CTE) in patients with failed back surgery syndrome (FBSS): A study protocol for a randomized controlled trial Journal of bodywork and movement therapies, 2021;26(0):428-434. 2021 [PMID: 33992278] (Human) Human
N Komabashir, F Suehiro, M Ishii, M Nishimura Efficacy of chitinase-3-like protein 1 as an in�vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells Regenerative Therapy, 2021;18(0):38-50. 2021 [PMID: 33869686] (Human) Human
LM Blanco-Col, N Méndez-Bar, AM Pello Láza, Á Aceña, N Tarín, C Cristóbal, J Martínez-M, Ó González-L, JL Martín-Ven, A Huelmos, C Gutiérrez-, M López-Cast, A Kallmeyer, E Cánovas, J Alonso, L López Besc, J Egido, Ó Lorenzo, J Tuñón MCP-1 Predicts Recurrent Cardiovascular Events in Patients with Persistent Inflammation Journal of Clinical Medicine, 2021;10(5):. 2021 [PMID: 33803115] (Human) Human
U Hoppmann, H Engler, S Krause, E Rottler, J Hoech, F Szabo, P Radermache, C Waller Systemic Catecholaminergic Deficiency in Depressed Patients with and without Coronary Artery Disease Journal of Clinical Medicine, 2021;10(5):. 2021 [PMID: 33801190] (Human) Human
RLI Crake, MR Strother, E Phillips, MP Doogue, M Zhang, CMA Frampton, BA Robinson, MJ Currie Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study Scientific Reports, 2021;11(1):5648. 2021 [PMID: 33707475] (Human) Human
Show All 200 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCL2/JE/MCP-1 (DCP00). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Other Available Formats

HRP DCP00
HRP DCP00
HRP DCP00

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Bioinformatics

Gene Symbol CCL2