TLR4 Antibody (MTS510) [DyLight 350]


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Product Details

Reactivity MuSpecies Glossary
Applications B/N, Flow
Please see the vial label for concentration. If unlisted please contact technical services.

TLR4 Antibody (MTS510) [DyLight 350] Summary

This antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (Akashi et al, 2000).
In FA, the antibody blocks activation of monocytes with LPS (Akashi et al. 2000). This antibody preferentially recognizes TLR4-MD-2 complex than of TLR4 alone. The optimal condition has to be determined for individual experiments.
IgG2a Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 350
DyLight 350 (A=353, E=432)
50mM Sodium Borate
0.05% Sodium Azide
Protein G purified


  • Blocking/Neutralizing
  • Flow Cytometry 1ul/1 million cells

Reactivity Notes

Mouse. Not yet tested in other species.


Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TLR4 Antibody (MTS510) [DyLight 350]

  • ARMD10
  • CD284 antigen
  • CD284
  • hTollhomolog of Drosophila toll
  • TOLL
  • toll-like receptor 4


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 405 Labeled NBP2-24865V
DyLight 405LS Labeled NBP2-24865V3
DyLight 488 Labeled NBP2-24865G
DyLight 550 Labeled NBP2-24865R
DyLight 650 Labeled NBP2-24865C
DyLight 680 Labeled NBP2-24865FR
DyLight 755 Labeled NBP2-24865IR
FITC Labeled NBP2-24450
HRP Labeled NBP2-24865H
PE Labeled NBP2-24741
PerCP Labeled NBP2-24865PCP

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Blogs on TLR4.

TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...  Read full blog post.

cIAP2 - balancing cell death and cell survival
The inhibitor of apoptosis proteins (IAPs) are important regulators of cell death and inflammation. The cellular inhibitor of apoptosis protein 2 (cIAP2) contains three Baculovirus IAP repeat (BIR) domains, a Ubiquitin associated (UBA) domain, and...  Read full blog post.

TLR4 - A Guardian of Innate Immunity
Toll-like receptor 4 (TLR4) belongs to the family of Toll-like receptors (TLR), and plays a main role in pathogen recognition and innate immunity system activation. The TLR family members are highly conserved proteins that all contain a high degree of...  Read full blog post.

IRAK4: The "master IRAK" critical for initiating immune responses
IRAK4, also known as Interleukin-1 receptor-associated kinase 4, is a serine/threonine-protein kinase that plays a critical role in initiating innate and adaptive immune responses against foreign pathogens. It activates NF-kappaB in both Toll-like rec...  Read full blog post.

TLR4: Playing Roles in Apoptosis and Autoimmunity
TLR4 (Toll-like receptor 4) is a member of the Toll-like receptor (TLR) family that plays a key role in pathogen recognition and activation of innate immunity. Scientists have found that TLRs are highly conserved from Drosophila to humans, with a high...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol TLR4

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