PGC1 alpha Antibody


Immunohistochemistry: PGC1 alpha Antibody [NB100-1750] - Immunohistochemistry: [NB100-1750] - Sample: FFPE section of human stomach adenocarcinoma. Antibody: Affinity purified rabbit anti-PGC-1 used at a dilution of more
Immunohistochemistry: PGC1 alpha Antibody [NB100-1750] - Sample: FFPE section of human colon adenocarcinoma. Antibody: Affinity purified rabbit anti-PGC-1 used at a dilution of 1:250. Detection: DAB

Product Details

Reactivity Hu, MuSpecies Glossary
Applications IHC, IHC-P

Order Details

PGC1 alpha Antibody Summary

The immunogen recognized by this antibody maps to a region between residue 250 and 300 of human peroxisome proliferative activated receptor, gamma, coactivator 1, alpha using the numbering given in SwissProt entry Q9UBK2 (GeneID 10891).
Immunogen affinity purified
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  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
Positive Control
PGC1 alpha Lysate (NBL1-14636)
Read Publications using
NB100-1750 in the following applications:

  • IHC
    1 publication
  • WB
    1 publication

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23892277).

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
TBS and 0.1% BSA
0.09% Sodium Azide
Immunogen affinity purified

Alternate Names for PGC1 alpha Antibody

  • LEM6
  • Ligand effect modulator 6
  • ligand effect modulator-6
  • peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
  • peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
  • PGC1 alpha
  • PGC1A
  • PGC-1-alpha
  • PGC1APGC-1(alpha)
  • PGC1peroxisome proliferative activated receptor, gamma, coactivator 1
  • PPAR gamma coactivator variant form
  • PPAR gamma coactivator-1
  • PPAR-gamma coactivator 1-alpha
  • PPARGC-1-alpha


The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PGC1 alpha Antibody (NB100-1750)(3)

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FAQs for PGC1 alpha Antibody (NB100-1750). (Showing 1 - 1 of 1 FAQs).

  1. Please differentiate me between PPAR and PGC clearly.i am confuse to know the differ these two. waiting for your reply
    • Thank you very much for contacting Novus Biologicals technical support team and sharing your query on the differences between PGC-1 alpha and PPAR. These are two different proteins encoded by their respective genes and serves different functions. PGC-1 alpha (PGC1A or PPAR gamma coactivator 1-alpha) is a transcriptional co-activator for steroid receptors and nuclear receptors, and it regulates diverse aspects of cellular physiology. It up-regulates the transcriptional activity of PPAR-gamma /thyroid hormone receptor on the uncoupling protein promoter; regulates the key mitochondrial genes involved in adaptive thermogenesis; implicates in the metabolic reprogramming in response to nutrients availability through the coordination of the expression of a wide array of genes involved in the regulation of glucose and fatty acid metabolism. Among our PGC-1 alpha antibodies, NBP1-04676 is our best selling product with nice customer feedback and citations in at least 13 research publications. PPAR (PPAR alpha) on the other hand is a ligand-activated transcription factor which gets activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine, and oleylethanolamide (a naturally occurring lipid that regulates satiety), and acts as a key regulator of lipid metabolism. It also acts as a receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. It regulates the peroxisomal beta-oxidation pathway of fatty acids, and also functions as transcription activator for the ACOX1 and P450 genes. We have a variety of PPAR alpha antibodies. I hope you will find this information helpful but please let me know if I can support you with anything else from my end. Thank you very much for choosing Novus Biologicals as your quality reagent supplier and we wish you the best with your research projects.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Gene Symbol PPARGC1A