mtTFA Antibody (18G102B2E11)


Western Blot: mtTFA Antibody (18G102B2E11) [NBP1-71648] - Analysis of mtTFA expression in HeLa whole cell lysate.
Immunocytochemistry/ Immunofluorescence: mtTFA Antibody (18G102B2E11) [NBP1-71648] - Immunostaining in HeLa cells. C1: DAPI staining 2 nuclei, C2: anti-mtTFA stain with Alexa Fluor 488 secondary ab (green), C3: more
Immunohistochemistry-Paraffin: mtTFA Antibody (18G102B2E11) [NBP1-71648] - IHC staining of mtTFA on human testis using DAB with hematoxylin counterstain.
Immunocytochemistry/ Immunofluorescence: mtTFA Antibody (18G102B2E11) [NBP1-71648] - Antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi (blue) and Phalloidin (red).
Simple Western: mtTFA Antibody (18G102B2E11) [NBP1-71648] - Simple Western lane view shows a specific band for mtTFA in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 more

Product Details

Reactivity Hu, RtSpecies Glossary
Applications WB, Simple Western, ICC/IF, IHC, IHC-P
1 mg/ml

mtTFA Antibody (18G102B2E11) Summary

Human mtTFA [Swiss-Prot# Q00059]
IgG2b Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tris-glycine, 150 mM NaCl
0.05% Sodium Azide
1 mg/ml
Protein G purified


  • Western Blot 1:1000
  • Simple Western 1:20
  • Immunocytochemistry/Immunofluorescence 1:50
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
Application Notes
This mtTFA (18G102B2E11) antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot, where a band can be seen around 20 - 25 kDa.In Simple Western only 10-15 uL of the recommended dilution is used per data point.
Read Publications using
NBP1-71648 in the following applications:

  • WB
    1 publication

Reactivity Notes

Human and rat.

Alternate Names for mtTFA Antibody (18G102B2E11)

  • mitochondrial transcription factor A
  • MTTF1
  • mtTFA
  • TCF-6
  • TCF6L1
  • TCF6L2Mitochondrial transcription factor 1
  • TCF6TCF6L3
  • Transcription factor 6
  • Transcription factor 6-like 2 (mitochondrial transcription factor)
  • Transcription factor 6-like 2
  • transcription factor A, mitochondrial


mtTFA (transcription factor A, mitochondrial) is an essential protein that binds mitochondrial DNA (mtDNA) with or without sequence specificity to control mitochondrial transcription initiation and mtDNA copy number. mtTFA exists as monomer localized in mitochondrion matrix nucleoid where it binds DNA and interacts with TFB1M/TFB2M. mtTFA associate with mitochondrial light strand promoter for controlling transcription and is essential for correct/efficient mtRNA polymerase promoter recognition. mtTFA is capable of unwinding DNA and bending mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes, and mtTFA is essential for controlling mtDNA levels as well as its organization/compaction. mtDNA is a multicopy, circular genome that is unquestionably required for respiratory function and interference with mitochondrial genome sequence fidelity, transcription, or translation can cause ATP insufficiency and several pathologies including progressive external ophthalmoplegia, amyotrophic lateral sclerosis (ALS), Alpers' disease, Parkinson's disease, Alzheimer's disease, aging, cardiovascular disease, diabetes and cancer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for mtTFA Antibody (NBP1-71648)(3)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 1 application: WB.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for mtTFA Antibody (NBP1-71648) (0)

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-71648AF405
Alexa Fluor (R) 488 Labeled NBP1-71648AF488
Alexa Fluor (R) 647 Labeled NBP1-71648AF647
Alexa Fluor (R) 700 Labeled NBP1-71648AF700
Allophycocyanin Labeled NBP1-71648APC
Biotin Labeled NBP1-71648B
DyLight 350 Labeled NBP1-71648UV
DyLight 405 Labeled NBP1-71648V
DyLight 405LS Labeled NBP1-71648V3
DyLight 488 Labeled NBP1-71648G
DyLight 550 Labeled NBP1-71648R
DyLight 650 Labeled NBP1-71648C
DyLight 680 Labeled NBP1-71648FR
DyLight 755 Labeled NBP1-71648IR
FITC Labeled NBP1-71648F
HRP Labeled NBP1-71648H
PE Labeled NBP1-71648PE
PerCP Labeled NBP1-71648PCP

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Contact Information

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Gene Symbol TFAM

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