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The incidence of obesity, diabetes and metabolic disorders is rising dramatically in developed countries. Given the ever increasing prevalence of obesity and our aging population, a better understanding of how our bodies metabolize and store food and the pathologies involved in these processes presents itself as a goal of increasing importance. Diseases associated with obesity include hypertension, dyslipidemia, type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, various cancers, sleep apnea and respiratory problems.
Browse our lipid and metabolism antibodies including:
At Novus Biologicals, we have a vast catalog of antibodies for all areas of biological research. Some of our most popular antibodies for lipid and metabolism research include GAPDH, Leptin and CD36. These antibodies are available as monoclonal, polyclonal and in conjugated forms. We aim to provide high quality products at the best possible price for your research needs.
ATP-binding Cassette 1, often referred to as ABCA1, is a membrane specific transporter gene, which functions as a cholesterol pump on both intra- and extracellular membranes. ABCA1 antibody preparations are used to detect and quantify its presence in immunoassays.
Mutations in the ABCA1 gene are implicated in high-density lipoprotein deficiency, coronary artery disease, atherosclerosis and Tangier's disease - research areas in which ABCA1 antibodies have proven useful.
Applications using ABCA1 antibody dilutions include Western blot, immunofluorescence, flow cytometry and immunocytochemistry.
Adiponectin is secreted by adipocytes; it plays an important role in linking adipose function to extracellular glucose regulation.
Adiponectin is significantly lower in the adipose tissue of patients with Type 2 diabetes, and adiponectin antibody immunoassays are used in both obesity and diabetes research. Adiponectin also regulates whole body homeostasis, and is implicated in many other diseases. Adiponectin antibody preparations are used in cardiovascular, stem cell, neurological and hormone research.
CD36 is a type B scavenger receptor important for lipid metabolism. CD36 is preferentially found within lipid rafts, which facilitates its association with receptors, signaling and adapter molecules. It is a necessary part of foam cell formation and, therefore, plays a key role in the formation of atherosclerotic lesions.
The CD36 antibody is made from an adenovirus that expresses recombinant murine CD36.
Cd36 antibodies are useful for Western blot analysis. Recently, CD36 antibody assays proved a link to lymphocytic leukaemia.
Leptin plays a key role in weight regulation by increasing energy expenditure and inhibiting food intake. Abnormalities in Leptin production are known to cause severe obesity. Leptin has a number of other roles, including inflammatory and immune response functions.
Leptin antibody preparations are routinely used in obesity, diabetes, and neurological illnesses research, including Multiple Sclerosis. Leptin antibody sera are derived from mice, sheep and rabbits.
At Novus Biologicals, we have a vast catalog of top quality antibodies covering all areas of biological research, at highly competitive prices.