FXR/NR1H4 Products

Antibodies
FXR/NR1H4 Antibody
FXR/NR1H4 Antibody
NBP2-16550
Species: Hu, Mu, Rt, Po, Bv, Rb
Applications: WB
Host: Rabbit Polyclonal
FXR/NR1H4 Antibody (1B10)
FXR/NR1H4 Antibody (1B10)
H00009971-M02
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Lysates
FXR/NR1H4 Overexpression Lysa ...
FXR/NR1H4 Overexpression Lysate (N...
NBL1-13769
Applications: WB
Proteins
FXR/NR1H4 Blocking Peptide
FXR/NR1H4 Blocking Peptide
NB400-153PEP
Species: Hu
Recombinant Human FXR/NR1H4 P ...
Recombinant Human FXR/NR1H4 Protein
H00009971-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
FXR/NR1H4 RNAi
FXR/NR1H4 RNAi
H00009971-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

FXR and LXR fall into a category of proteins termed orphan receptors; because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. The steroid receptor superfamily acts through direct association with DNA sequences known as hormone response elements (HREs) and bind DNA as either homo- or heterodimers. The promiscuous mediator of heterodimerization, RXR, is the receptor for 9-cis retinoic acid, and dimerizes with VDR, TR, PPAR, as well as several novel receptors including LXR (also referred to as RLD-1) and FXR.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Mouse
Product By Gene ID 9971
Alternate Names
  • Nuclear receptor subfamily 1 group H member 4
  • Farnesol receptor HRR-1
  • farnesoid X receptor
  • Farnesoid X-activated receptor
  • bile acid receptor
  • HRR-1
  • HRR1MGC163445
  • RIP14RXR-interacting protein 14
  • FXRBAR
  • Retinoid X receptor-interacting protein 14
  • nuclear receptor subfamily 1, group H, member 4

Research Areas for FXR/NR1H4

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Lipid and Metabolism
Signal Transduction

PTMs for FXR/NR1H4

Learn more about PTMs related to FXR/NR1H4.

Phosphorylation
Amidation
Oxidation

Bioinformatics Tool for FXR/NR1H4

Discover related pathways, diseases and genes to FXR/NR1H4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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