PGC1 alpha Products

Antibodies
PGC1 alpha Antibody
PGC1 alpha Antibody
NBP1-04676
Species: Hu, Mu, Rt, Ha, Sq, Ca, Eq, Pm
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Host: Rabbit Polyclonal
PGC1 alpha [p Ser571] Antibod ...
PGC1 alpha [p Ser571] Antibody [Un...
AF6650
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
PGC1 alpha Antibody
PGC1 alpha Antibody
NB100-60955
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
PGC1 alpha Overexpression Lys ...
PGC1 alpha Overexpression Lysate (...
NBL1-14636
Applications: WB
Proteins
Recombinant Human PGC1 alpha ...
Recombinant Human PGC1 alpha Protein
H00010891-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
PGC1 alpha RNAi
PGC1 alpha RNAi
H00010891-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha) is a transcriptional coactivator responsible for regulating genes involved in energy metabolism. PGC1a is a master integrator of external signals. The protein interacts with multiple transcription factors and acts as a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis. Some PGC1a activators include reactive oxygen species and reactive nitrogen species, as well as CREB, Akt and SIRT1 proteins. Additional functions of PGC1 alpha include regulating muscle fiber type determination, blood pressure, cellular cholesterol homoeostasis, and obesity development.

Recently PGC-1alpha has been suggested as a potential therapy for Parkinson's Disease, as the protein is thought to protect mitochondrial metabolism.

The PPARGC1A gene is also known as human accelerated region 20, and is thought to have played a key role in differentiating humans and apes.

Bioinformatics

Uniprot Human
Human
Product By Gene ID 10891
Alternate Names
  • PGC1A
  • PPARGC-1-alpha
  • PPAR gamma coactivator-1
  • PGC-1-alpha
  • PPAR gamma coactivator variant form
  • LEM6
  • peroxisome proliferator-activated receptor gamma coactivator 1-alpha
  • Ligand effect modulator 6
  • ligand effect modulator-6
  • peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
  • PPARGC1PGC-1v
  • PGC1APGC-1(alpha)
  • PGC1peroxisome proliferative activated receptor, gamma, coactivator 1
  • PPAR-gamma coactivator 1-alpha
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Research Areas for PGC1 alpha

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cholesterol Metabolism
Chromatin Research
Diabetes Research
Lipid and Metabolism
mTOR Pathway
Neuroscience
Transcription Factors and Regulators

Bioinformatics Tool for PGC1 alpha

Discover related pathways, diseases and genes to PGC1 alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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