Applications: WB, ELISA, Flow, CyTOF-ready
Host: Mouse Monoclonal
Applications: WB, ELISA, PA
Applications: RNAi, RNAi SP
PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. PGC-1 beta is also involved in activation of nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. Ectopic expression of this protein has been shown to lead to increased mitochondrial numbers and basal oxygen consumption.
|Product By Gene ID
- PGC1Bgamma, coactivator 1, beta
- peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Bioinformatics Tool for PGC-1 beta
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