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Sirtuin 1/SIRT1 Products

Antibodies
Sirtuin 1/SIRT1 Antibody - BS ...
Sirtuin 1/SIRT1 Antibody - BSA Free
NBP2-27205
Species: Hu, Mu, Rt, Po, Am, Bv, Ca, Ch, ChHa, Eq, Fe, Ha, Pm, Rb, Av, Pm, Pm, Pm-Or, Re
Applications: WB, Simple Western
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Sirtuin 1/SIRT1 Antibody
Sirtuin 1/SIRT1 Antibody
NBP1-49540
Species: Hu
Applications: WB, Simple Western, ICC/IF, IHC, KO, Mycoplasma
Host: Rabbit Polyclonal
ELISA Kits
Rat Sirtuin 1/SIRT1 ELISA Kit ...
Rat Sirtuin 1/SIRT1 ELISA Kit (Col...
NBP2-80302
Species: Rt
Applications: ELISA
Human Sirtuin 1/SIRT1 ELISA K ...
Human Sirtuin 1/SIRT1 ELISA Kit (C...
NBP2-80300
Species: Hu
Applications: ELISA
Mouse Sirtuin 1/SIRT1 ELISA K ...
Mouse Sirtuin 1/SIRT1 ELISA Kit (C...
NBP2-80301
Species: Mu
Applications: ELISA
Kits
Sirtuin 1/SIRT1 Assay Kit (Fl ...
Sirtuin 1/SIRT1 Assay Kit (Fluorom...
KA1366
Species: Mu
Applications: Func, Enzyme Activity, NULL
Lysates
Sirtuin 1/SIRT1 Overexpressio ...
Sirtuin 1/SIRT1 Overexpression Lysate
NBP2-04329
Species: Hu
Applications: WB
Proteins
Recombinant Human Sirtuin 1/S ...
Recombinant Human Sirtuin 1/SIRT1 ...
7714-DA
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Sirtuin 1/SIRT1 Recombinant P ...
Sirtuin 1/SIRT1 Recombinant Protei...
NBP1-87038PEP
Species: Hu
Applications: AC
Sirtuin 1/SIRT1 Recombinant P ...
Sirtuin 1/SIRT1 Recombinant Protei...
NBP2-56849PEP
Species: Hu
Applications: AC

Description

The S. cerevisiae silent information regulator 2 (Sir2) protein is an NAD+-dependent histone deacetylase (HDACs) that plays a critical role in transcriptional silencing, genome stability, and longevity (1-2). Part of the Sirtuin family (Sir2, Sir3, Sir3), yeast Sir2 is the founding member of Class III HDACs. A human homologue of Sir2 , SIRT1, regulates the activity of the p53 tumor suppressor and inhibits apoptosis (3-4).

Bioinformatics

Product By Gene ID 23411
Alternate Names
  • EC 3.5.1
  • S. cerevisiae, homolog) 1
  • SIR2alpha
  • SIR2L1
  • SIR2-like protein 1
  • SIRT1
  • Sirtuin 1

Research Areas for Sirtuin 1/SIRT1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Chromatin Research
Cognition and Behavior
DNA Repair
Epigenetics