Hu, Mu, Rt, PmApplications:
WB, ELISA, Flow, Flow-IC, ICC/IF, IHC, IHC-PHost:
Hu, Mu, Po, Am, Bv, Ca, Ch, ChHa, Eq, Fe, Pm, RbApplications:
WB, Simple WesternHost:
Applications: WB, Simple Western, ICC/IF, IHC, IHC-P, KD, KO
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA, AP
Applications: RNAi, RNAi SP
The S. cerevisiae silent information regulator 2 (Sir2) protein is an NAD+-dependent histone deacetylase (HDACs) that plays a critical role in transcriptional silencing, genome stability, and longevity (1-2). Part of the Sirtuin family (Sir2, Sir3, Sir3), yeast Sir2 is the founding member of Class III HDACs. A human homologue of Sir2, SIRT1, regulates the activity of the p53 tumor suppressor and inhibits apoptosis (3-4).
Bioinformatics Tool for Sirtuin 1/SIRT1
Discover related pathways, diseases and genes to Sirtuin 1/SIRT1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.