SRC1 Products

Antibodies
SRC1 Antibody
SRC1 Antibody
NB300-541
Species: Hu, Mu, Rt, Am, Av
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr
Host: Rabbit Polyclonal
SRC1 Antibody
SRC1 Antibody
NB100-312
Species: Hu
Applications: WB, PLA
Host: Rabbit Polyclonal
Lysates
SRC1 Overexpression Lysate (N ...
SRC1 Overexpression Lysate (Native)
NBP2-05443
Applications: WB
SRC1 Overexpression Lysate (N ...
SRC1 Overexpression Lysate (Native)
NBL1-13515
Applications: WB
SRC1 Overexpression Lysate (N ...
SRC1 Overexpression Lysate (Native)
NBP2-05442
Proteins
SRC1 Partial Recombinant Prot ...
SRC1 Partial Recombinant Protein
H00008648-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
SRC1 RNAi
SRC1 RNAi
H00008648-R02
Species: Hu
SRC1 RNAi
SRC1 RNAi
H00008648-R03
Species: Hu
SRC1 RNAi
SRC1 RNAi
H00008648-R01
Species: Hu

Description

Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is Steroid Receptor Coactivator-1 (SRC 1).SRC 1 has been shown to interact with and stimulate the transcriptional activity of estrogen, progesterone, retinoic acid, thyroid and glucocorticoid receptors, as well as retinoic X receptor (RXR) in a ligand dependent manner. The amino terminal region of SRC 1 contains a PAS-A-basic helix-loop-helix homology domain which has previously been shown to be dimerization domains in other nuclear transcription factors including the aryl hydrocarbon (Ah) receptor and its heterodimerization partner, ARNT. The carboxy-terminal region of SRC 1 has been shown to possess histone acetyltransferase activity specific primarily for histones H3 & H4.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 8648
Alternate Names
  • EC 2.3.1.48
  • SRC-1
  • Steroid receptor coactivator 1
  • BHLHE74
  • Renal carcinoma antigen NY-REN-52
  • steroid receptor coactivator-1
  • Protein Hin-2
  • PAX3/NCOA1 fusion protein
  • Class E basic helix-loop-helix protein 74
  • Hin-2 protein
  • NCoA-1
  • bHLHe42
  • KAT13A
  • RIP160bHLHe74F-SRC-1
  • SRC1MGC129720
  • MGC129719
  • nuclear receptor coactivator 1

Research Areas for SRC1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Transcription Factors and Regulators

Bioinformatics Tool for SRC1

Discover related pathways, diseases and genes to SRC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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