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Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, IP, CyTOF-ready
Clone
23C6
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB100-2677AF350
Alexa Fluor 405
NB100-2677AF405
Alexa Fluor 488
NB100-2677AF488
Alexa Fluor 532
NB100-2677AF532
Alexa Fluor 594
NB100-2677AF594
Alexa Fluor 647
NB100-2677AF647
Alexa Fluor 700
NB100-2677AF700
Alexa Fluor 750
NB100-2677AF750
Allophycocyanin
NB100-2677APC
Allophycocyanin/Cy7
NB100-2677APCCY7
Biotin
NB100-2677B
CoraFluor 1
NB100-2677CL1
DyLight 350
NB100-2677UV
DyLight 405
NB100-2677V
DyLight 488
NB100-2677G
DyLight 550
NB100-2677R
DyLight 594
NB100-2677DL594
DyLight 650
NB100-2677C
DyLight 680
NB100-2677FR
DyLight 755
NB100-2677IR
FITC
NB100-2677F
HRP
NB100-2677H
Janelia Fluor 525
NB100-2677JF525
Janelia Fluor 549
NB100-2677JF549
Janelia Fluor 646
NB100-2677JF646
Janelia Fluor 669
NB100-2677JF669
PE
NB100-2677PE
PE/Atto594
NB100-2677PEATT594
PE/Cy5.5
NB100-2677PECY55
PE/Cy7
NB100-2677PECY7
PerCP
NB100-2677PCP
Unconjugated
NB100-2677
mFluor Violet 450 SE
NB100-2677MFV450
mFluor Violet 500 SE
NB100-2677MFV500
mFluor Violet 610 SE
NB100-2677MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB100-2677
BSA Free
NB100-2677
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Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free Summary

Immunogen
A cell suspension containing osteoclasts from osteoclastomas.
Localization
Cell Membrane
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ITGAV
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
Application Notes
Positive control(s): Tonsil.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein A or G purified

Alternate Names for Integrin alpha V beta 3 Antibody (23C6) - Azide and BSA Free

  • antigen identified by monoclonal L230
  • CD51 antigen
  • CD51
  • Integrin alpha V beta 3
  • integrin alpha-V
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • MSK8
  • Vitronectin receptor subunit alpha
  • VNRADKFZp686A08142

Background

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha V beta 3 is the predominant integrin of osteoclasts (bone resorbing cells) and is upregulated in malignant melanoma. Integrin alpha V beta 3 binds to a range of ECM proteins (e.g. vitronectin, fibrinogen, fibronectin) via an Arg-Gly-Asp (RGD) motif.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGAV