Integrin beta 1/CD29 Antibody (P5D2) [Unconjugated]


Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB17781, filled histogram) or isotype control antibody (Catalog # MAB002, open more
A549 human lung carcinoma cell line was stained with Mouse Anti-Human Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB17781, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), more
Integrin beta 1/CD29 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) using Mouse Anti-Human Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB17781) at 25 µg/mL for 3 hours at more
Genetic Strategies: Integrin beta 1/CD29 knockout A549 human lung carcinoma cell line was stained with Mouse Anti-Human Integrin beta 1/CD29 Monoclonal Antibody (Catalog # MAB17781, filled histogram) or isotype more

Product Details

Reactivity HuSpecies Glossary
Applications Flow, IP, B/N, CyTOF-ready, ICC/IF, KO
Validated by:

Genetic Strategies


Order Details

Integrin beta 1/CD29 Antibody (P5D2) [Unconjugated] Summary

Human skin keratinocytes
Detects human Integrin beta 1/CD29.
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Blockade of Receptor-ligand Interaction
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
  • Immunocytochemistry 8-25 ug/mL
  • Immunoprecipitation
  • Knockout Validated
Read Publications using
MAB17781 in the following applications:

Packaging, Storage & Formulations

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
No Preservative
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Integrin beta 1/CD29 Antibody (P5D2) [Unconjugated]

  • CD29 antigen
  • CD29
  • Fibronectin receptor subunit beta
  • Integrin beta 1
  • integrin beta-1
  • integrin VLA-4 beta subunit
  • integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includesMDF2, MSK12)
  • ITGB1
  • MDF2
  • MSK12
  • very late activation protein, beta polypeptide
  • VLA-4 subunit beta


The Integrin beta 1 subunit, also known as CD29, associates with at least ten different Integrin alpha subunits. It regulates not only its multiple ligands, but activates a signaling cascade in its expressing cells. CD29 is proposed to play a role in cell adhesion, apoptosis, and differentiation (1,2). Over amino acids (aa) 21-728, human and mouse share 92% aa sequence identity.
  1. Barkan, D. and A.F. Chambers (2011) Clin. Cancer Res. 17:7219.
  2. Humphries, M.J. (2000) Biochem. Soc. Trans. 28:311.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: IHC, KO, WB
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Applications: AdBlk, CyTOF-ready, Flow, ICC
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Applications: CyTOF-ready, Flow, IHC, WB
Species: Hu
Applications: CyTOF-ready, Flow, Simple Western, WB
Species: Hu
Applications: ELISA
Species: Hu
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Species: Ca, Hu, Pm, Mu, Rt
Applications: IHC, IHC-P, IP, WB
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
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Applications: Flow, ICC/IF, IHC-FrFl, IHC, IHC-Fr, IP, WB
Species: Bv, Ce, ChHa, Hu, Pm, Mu, Rt, RM
Applications: Dual ISH-IHC, Flow-CS, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, ISH, Simple Western, Single-Cell Western, WB
Species: Hu
Applications: BA

Publications for Integrin beta 1/CD29 Antibody (MAB17781)(24)

We have publications tested in 3 confirmed species: Human, Mouse, Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque).

We have publications tested in 8 applications: Bioassay, Blocking, Flow Cytometry, ICC, IF, IHC, IHC-Fr, Neutralization.

Filter By Application
Flow Cytometry
All Applications
Filter By Species
Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
All Species
Showing Publications 1 - 10 of 24. Show All 24 Publications.
Publications using MAB17781 Applications Species
SI Gringhuis, TM Kaptein, EBM Remmerswaa, A Drewniak, BA Wevers, B Theelen, GRAM D'Haens, T Boekhout, TBH Geijtenbee Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs Nature Immunology, 2022-12-01;0(0):. 2022-12-01 [PMID: 36456734] (Neutralization, Human) Neutralization Human
G Liu, R Liu, Y Shan, C Sun Marine bacterial exopolysaccharide EPS11 inhibits migration and invasion of liver cancer cells by directly targeting collagen I The Journal of Biological Chemistry, 2021-08-28;0(0):101133. 2021-08-28 [PMID: 34461092] (Neutralization, Human) Neutralization Human
PK Myint, A Ito, MG Appiah, G Obeng, S Darkwah, E Kawamoto, A Gaowa, EJ Park, M Shimaoka Irisin supports integrin-mediated cell adhesion of lymphocytes Biochemistry and Biophysics Reports, 2021-03-08;26(0):100977. 2021-03-08 [PMID: 33732908] (Flow Cytometry, Neutralization, Human) Flow Cytometry, Neutralization Human
E Kawamoto, N Nago, T Okamoto, A Gaowa, A Masui-Ito, Y Akama, S Darkwah, MG Appiah, PK Myint, G Obeng, A Ito, S Caidengbat, R Esumi, T Yamaguchi, EJ Park, H Imai, M Shimaoka The Lectin-Like Domain of Thrombomodulin Inhibits &amp;beta1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin Biomedicines, 2021-02-07;9(2):. 2021-02-07 [PMID: 33562346] (Flow Cytometry, Human) Flow Cytometry Human
S Yuan, C Zhang, Y Zhu, B Wang Neohesperidin Ameliorates Steroid-Induced Osteonecrosis of the Femoral Head by Inhibiting the Histone Modification of lncRNA HOTAIR Drug Design, Development and Therapy, 2020-12-07;14(0):5419-5430. 2020-12-07 [PMID: 33324039] (Flow Cytometry, Mouse) Flow Cytometry Mouse
G Luthria, R Li, S Wang, M Prytyskach, RH Kohler, DA Lauffenbur, TJ Mitchison, R Weissleder, MA Miller In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells Nat Commun, 2020-07-14;11(1):3521. 2020-07-14 [PMID: 32665556] (Bioassay, Human) Bioassay Human
SP Davies, GM Reynolds, AL Wilkinson, X Li, R Rose, M Leekha, YS Liu, R Gandhi, E Buckroyd, J Grove, NM Barnes, RC May, SG Hubscher, DH Adams, Y Huang, O Qureshi, Z Stamataki Hepatocytes Delete Regulatory T Cells by Enclysis, a CD4+ T Cell Engulfment Process Cell Rep, 2019-11-05;29(6):1610-1620.e4. 2019-11-05 [PMID: 31693899] (IF, Human) IF Human
A Rajan, BD Persson, L Frängsmyr, A Olofsson, L Sandblad, J Heino, Y Takada, AP Mould, LM Schnapp, J Gall, N Arnberg Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells Sci Rep, 2018-07-03;8(1):10019. 2018-07-03 [PMID: 29968781] (Flow Cytometry) Flow Cytometry
SF Ahmad, JK Brown, LL Campbell, M Koscielnia, C Oliver, N Wheelhouse, G Entrican, S McFee, GS Wills, MO McClure, PJ Horner, S Gaikoumelo, KF Lee, HOD Critchley, WC Duncan, AW Horne Pelvic Chlamydial Infection Predisposes to Ectopic Pregnancy by Upregulating Integrin ?1 to Promote Embryo-tubal Attachment EBioMedicine, 2018-02-23;0(0):. 2018-02-23 [PMID: 29500127] (Neutralization, Human) Neutralization Human
CJ Lovitt, TB Shelper, VM Avery Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins BMC Cancer, 2018-01-06;18(1):41. 2018-01-06 [PMID: 29304770] (Neutralization, Human) Neutralization Human
Show All 24 Publications.

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FAQs for Integrin beta 1/CD29 Antibody (MAB17781). (Showing 1 - 1 of 1 FAQs).

  1. I'm looking for a good antibody for integrins that works in rats. I would need it for Western Blot, Immunocyto- as well as Immunohistochemistry. I'm especially interested in beta1.
    • I would recommend NB110-57123 as it has been validated using rat samples in WB, IHC-P, and FACS. Although we do not list ICC on the datasheet for this antibody I believe it will work in ICC because it works in Flow Cytometry and has been validated to stain tissue. We have several other Integrin targets. To search for what you are looking for I recommend typing Integrin into the search area at the top of our website, then review the list of suggested targets that poplulate below the search. Once you click on a particular Integrin you can narrow the results with our filter. I recommend filtering to primary antibodies, by target name, species of interest you can filter to rat. If you so choose you can also filter further by application, host, clonality, etc.

Secondary Antibodies


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Integrin Beta 1/CD29 - a cell adhesion and cell signaling protein with diverse functions
Integrins are a large family of trasmembrane proteins involved in cell adhesion and form a link between the intracellular cyskeletal proteins and extracellular matrix proteins. Integrins exist as heterodimers consisting of alpha and beta subunits. ...  Read full blog post.

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Gene Symbol ITGB1