beta-Actin Antibody (AC-15)

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - MCDK cells induced with C22H24N2O8 to control the expression of the gene of interest. Beta-actin blocking confirms the albumin assay showing that an equal amount of lysate was loaded in each lane.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Beta-Actin expression in Fibroblast Hs68 cell lysate using anti-beta-Actin antibody. Image from verified customer review.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Cell line lysates were separated on SDS-PAGE and probed with 1:5000 Monoclonal Anti-beta-Actin Clone: AC-15 . The antibody was developed using Goat Anti-Mouse IgG-Peroxidase and a chemiluminescent substrate.Lanes: 1. HeLa, 2. JURKAT, 3. COS7, 4. NIH-3T3, 5. PC-12, 6. RAT2, 7.CHO, 8. MDBK, 9. MDCK

Immunocytochemistry/Immunofluorescence: beta-Actin Antibody (AC-15) [NB600-501] - Analysis of beta-Actin antibody on mouse fibroblasts. Image from verified customer review.

Immunohistochemistry: beta-Actin Antibody (AC-15) [NB600-501] - Staining of formalin-fixed, paraffin-embedded human heart sections with 1:1000 Monoclonal Anti-beta-Actin Clone: AC-15.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Analysis of beta-Actin in bovine whole skeletal muscle lysate. Image from verified customer review.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - Whole cell extract of human fibroblasts was separated on SDS-PAGE and blotted with Monoclonal Anti-beta-Actin. The antibody was developed with Goat Anti-Mouse IgG, Peroxidase conjugate and AEC substrate. Lanes A: Antibody dilution 1:5,000 B: Negative control (only secondary antibody).

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - beta-Actin expression in human glioma cells using anti-beta-Actin antibody. Image from verified customer review.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - HEK293T cells transfected with Niaph virus Matrix Protein, expression 24h later. This image was submitted via customer review.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - MMP-11 expression in oral cancer cell lines and the MMP-11 knockdown in SCC9 cells reduce cell migration. Western blot analysis showing the expression of MMP-11 protein in five oral cancer cell lines. Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0113129), licensed under a CC-BY license.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - HSP90 and HSP70 interact with PABPN1. Interaction of PABPN1 with HSP90. Lysates from HEK293 cells transfected with Flag-HSP90 and GFP-tagged A17-PABPN1 were immunoprecipitated with an anti-Flag antibody. Immunoprecipitates (IP) were analyzed by Western blot (IB).Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0138936), licensed under a CC-BY license.

Western Blot: beta-Actin Antibody (AC-15) [NB600-501] - GFAP and IL-6 are elevated in cultures of spinal cord compared to cortical astrocytes. ((G, H) Analysis of protein homogenates from brain or spinal cord astrocyte cultures also demonstrated higher levels of GFAP expression, but no differences in ALDH1L1. Beta-Actin is included as a loading control. Image collected and cropped by CiteAb from the following publication (//dx.plos.org/10.1371/journal.pone.0180697), licensed under a CC-BY license.

Immunocytochemistry/Immunofluorescence: beta-Actin Antibody (AC-15) [NB600-501] - Cultured FS-11 human fibroblast cell line stained using Monoclonal Anti-Beta-Actin, Clone No. AC-15 (NB600-501).

Immunocytochemistry/Immunofluorescence: beta-Actin Antibody (AC-15) [NB600-501] - HS-68 cells.

Simple Western: beta-Actin Antibody (AC-15) [NB600-501] - Analysis using the HRP conjugate of NB600-501. Electropherogram image(s) of corresponding Simple Western lane view. Beta-Actin antibody was used at 1:500 dilution on Hela, MCF-7, SH-SY5Y, & Jurkat lysate(s).

Simple Western: beta-Actin Antibody (AC-15) [NB600-501] - Analysis using the HRP conjugate of NB600-501. Image shows a specific band for Beta-Actin in 0.2 mg/mL of Hela, MCF-7, SH-SY5Y, & Jurkat lysate(s). This experiment was performed under reducing conditions using the 12-230 kDa separation system. * Non-specific interaction with the 230 kDa Simple Western standard may be seen with this antibody.

• Reactivity: Hu, Mu, Rt, Po, Bv, Ca, Ch, Fe, Fi, Gp, Ha, Le, Ma, Pm, Rb, Sh, Sq, Tr, Ze, Dr(-)
• Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC, IP, ChIP, KD, KO
• Clone: AC-15
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

beta-Actin Antibody (AC-15) Summary

• Immunogen: This beta-Actin Antibody (AC-15) was made to a slightly modified Beta-cytoplasmic actin N-terminal peptide, Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys, conjugated to KLH.
• Epitope: N-terminus of the beta isoform of actin.
• Specificity: In staining of chicken gizzard ultrathin tissue cryosections, the antibody labels the dense bodies and longitudinal channels linking consecutive dense bodies that are also occupied by desmin and the membrane-associated dense plaque. It does not stain adult cardiac and skeletal muscles except for traces due to contaminations of the sample with non-muscle cells, or if embryonic tissue is being used. The epitope recognized by the antibody is resistant to formalin-fixing and paraffin-embedding.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ACTB
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP)
  • ELISA 1:100 - 1:2000
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence 1:1000 - 1:2000
  • Immunohistochemistry 1:10 - 1:500
  • Immunohistochemistry-Frozen 1:500
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Knockdown Validated
  • Knockout Validated
  • Simple Western 1:25
  • Western Blot 1:5000 - 1:10000
• Application Notes: Simple Western reported by an internal validation. Separated by Size-All, antibody dilution of 1:25-1:100; matrix was 12-230 kDa.
• Theoretical MW: 42 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

The antibody cross reacts with beta-actin expressing cells in carp, leech tissues (Hirudo medicinalis), ground squirrel. Does not cross react with adult cardiac, skeletal muscle, drosophila or amoeba beta actin. Mammal reactivity and Hamster reactivity reported in scientific literature (PMID: 25130694 and 24478435 respectively). Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information. Human reactivity reported in scientific literature (PMID:32938681) Use in Turkey reported in scientific literature (PMID:27816932).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: 15mM Sodium Azide
• Purity: Unpurified

Alternate Names for beta-Actin Antibody (AC-15)

• ACTB
• actin, beta
• actin, cytoplasmic 1
• anti-beta actin
• B-Actin
• beta actin (ac-15)
• Beta Actin
• beta cytoskeletal actin
• beta-actin ac 15
• beta-actin ac15
• beta-actin ac-15
• betaActin
• beta-Actin
• BRWS1
• I(2)-Actin
• PS1TP5-binding protein 1
• PS1TP5BP1

Background

Actin is a highly conserved protein involved in cell motility, structure, and integrity. Six functional actin isoforms exist and were named based on their electrophoretic mobility and distribution including alpha-cardiac muscle actin (aCAA), alpha-skeletal muscle actin (aSKA), alpha-smooth muscle actin (aSMA), beta-cytoplasmic actin (bCYA), gamma-cytoplasmic actin (gCYA) and gamma-smooth muscle actin (gSMA) (1). The cytoplasmic isoforms, beta-actin and gamma-actin, are nearly identical, differing by only 4 amino acids at the N-terminus with a theoretical molecular weight of 42 kDa (2). Beta-actin is ubiquitously expressed in eukaryotic cells and considered a housekeeping gene which is frequently used as a loading control for assays involving protein detection, such as Western blotting (3,4).

References

1. Vandekerckhove J, Weber K. 1978. At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide. J Mol Biol. 126(4):783-802. PMID: 745245

2. Gimona M, Vandekerckhove J, Goethals M, Herzog M, Lando Z, Small JV. (1994) Beta-actin specific monoclonal antibody. Cell Motil Cytoskeleton. 27(2):108-16. PMID: 8162619

3. Holden VI, Lenio S, Kuick R, Ramakrishnan SK, Shah YM, Bachman MA. (2014) Bacterial siderophores that evade or overwhelm Lipocalin 2 induce HIF-1a and pro-inflammatory cytokine secretion in cultured respiratory epithelial cells Infect Immun. 82(9):3826-36 PMID: 24980968

4. Tsai WL, Yeh PH, Tsai CY, Ting CT, Chiu YH, Tao MH, Li WC, Hung SC. (2016) Efficient Programming of Human Mesenchymal Stem Cell Derived Hepatocytes by Epigenetic Regulations. J. Gastroenterol. Hepatol. 32(1):261-269. PMID: 27218433

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for beta-Actin Antibody (NB600-501)(554)

Publications using NB600-501

• Honkanen TJ, Luukkainen MEK, Koivunen JP. Role of human epidermal growth factor receptor 3 in treatment resistance of anaplastic lymphoma kinase translocated non-small cell lung cancer Cancer Biol Ther 2023-12-31 [PMID: 37722715] (WB)
• Cottarelli A, Shahriar S, Arac A et al. Rab7a activation promotes degradation of select tight junction proteins at the blood-brain barrier after ischemic stroke bioRxiv 2023-08-31 [PMID: 37693406]
• Papadaki V, Erpapazoglou Z, Kokkori M et al. IQGAP1 mediates the communication between the nucleus and the mitochondria via NDUFS4 alternative splicing NAR Cancer 2023-08-24 [PMID: 37636315]
• Pai YL, Lin YJ, Peng WH et al. The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy Cell Death & Disease 2023-08-22 [PMID: 37607937]
• Bow YD, Ko CC, Chang WT et al. A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage Cancer Cell International 2023-08-16 [PMID: 37587444] (WB)
• Shih PC, Mao YW, Hu JW et al. Development of Ultrapure and Potent Tannic Acids as a Pan-coronal Antiviral Therapeutic ACS Pharmacology & Translational Science 2022-06-10 [PMID: 37582235] (WB, B/N)
• Nishikawa Y, Matsuo Y, Watanabe R et al. Hepatocyte-specific damage in acute toxicity of sodium ferrous citrate: Presentation of a human autopsy case and experimental results in mice Toxicology reports 2023-05-30 [PMID: 37304377] (WB, Mouse)
• Sidor K, Jeznach A, Hoser G, Skirecki T 1-Methylnicotinamide (1-MNA) inhibits the activation of the NLRP3 inflammasome in human macrophages International immunopharmacology 2023-06-06 [PMID: 37290319] (WB, Human)
• Rong Z, Yang L, Chen Y et al. Sophoridine alleviates hyperalgesia and anxiety-like behavior in an inflammatory pain mouse model induced by complete freund's adjuvant Molecular pain 2023-05-19 [PMID: 37207346] (WB, Mouse)
• Douglas C, Lomeli N, Lepe J et al. Discovery and Validation of Novel LonP1 and Proteasome Inhibitor in IDH1-R132H Malignant Astrocytoma Models bioRxiv 2023-04-21 [PMID: 37131786] (WB, B/N)
• Chiu KW, Chen HY, Chen CL et al. Attenuation of Endoplasmic Reticulum Stress Enhances Carvacrol-Induced Apoptosis in Osteosarcoma Cell Lines Life (Basel, Switzerland) 2023-03-09 [PMID: 36983900] (WB, Human)
• Cheng YS, Chen HY, Lin YC et al. The MAEL expression in mitochondria of human spermatozoa and the association with asthenozoospermia Andrology 2023-02-13 [PMID: 36779514]
• Dougherty J, Harvey K, Liou A et al. Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas PloS one 2023-02-02 [PMID: 36730269]
• Hamel KM The Age-Dependent Characterization of the ER-Alpha Positive Breast Cancer Tumor Microenvironment Thesis 2021-01-01
• Ngo J, Choi DW, Stanley IA et al. Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl-CoA The EMBO journal 2023-03-14 [PMID: 36917141]
• Davis C, Ammi A, Zhu W et al. Low-Intensity Ultrasound Reduces Brain Infarct Size by Upregulating Phosphorylated Endothelial Nitric Oxide in Mouse Model of Middle Cerebral Artery Occlusion Ultrasound in Medicine & Biology 2023-02-01 [PMID: 36739244] (WB, Mouse)
  
  Details:
  Dilution used in WB 1:8,000
• Brownrigg GP, Xia YH, Chu CMJ et al. Sex differences in islet stress responses support female ? cell resilience Molecular Metabolism 2023-03-01 [PMID: 36690328] (WB, B/N)
• Wang C, Chan D, Hendrickson E Kinome-wide screening uncovers a role for Bromodomain Protein 3 in DNA double-stranded break repair DNA Repair 2022-12-01 [PMID: 36608404]
• Kuo FC, Wang YT, Liu CH et al. LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1 Cancer cell international 2022-12-09 [PMID: 36494673] (WB, Human)
  
  Details:
  Dilution used in WB 1:10,000
• Laoukili J, van Schelven S, Kucukkose E et al. BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis Cell reports 2022-11-29 [PMID: 36450250] (WB, Human)
• El Assar M, GarcIa-Rojo E, Sevilleja-Ortiz A Et al. Functional Role of STIM-1 and Orai1 in Human Microvascular Aging Cells 2022-11-26 [PMID: 36429103] (WB, IF/IHC, Human)
  
  Details:
  Citation using the HRP version of this antibody.
• Pakalniskyte D, SchOnberger T, Strobel B et al. Rosa26-LSL-dCas9-VPR: a versatile mouse model for tissue specific and simultaneous activation of multiple genes for drug discovery Scientific reports 2022-11-10 [PMID: 36357523] (Simple Western, Mouse)
  
  Details:
  Dilution used in Simple Western 1:20
• Vassal M, Pereira CD, Martins F et al. Different Strategies to Attenuate the Toxic Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells Nanomaterials (Basel, Switzerland) 2022-10-11 [PMID: 36296751] (WB, Mouse)
• Song L, Yao X, Li H et al. Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer Molecular cell 2022-10-18 [PMID: 36272410] (WB, Human)
• Tsai YT, Huang HC, Kao ST et al. Neuroprotective Effects of Alpinia oxyphylla Miq against Mitochondria-Related Apoptosis by the Interactions between Upregulated p38 MAPK Signaling and Downregulated JNK Signaling in the Subacute Phase of Cerebral Ischemia-Reperfusion in Rats The American journal of Chinese medicine 2022-10-20 [PMID: 36266752] (WB)
• Tiberti M, Di Leo L, Vistesen MV et al. The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma Cell Death & Disease 2022-10-15 [PMID: 36243772]
• Wang Y, Liao J, Chen K Et Al. Lumbrokinase regulates endoplasmic reticulum stress through IRE1 signaling to improve neurological deficits in ischemic stroke Research Square 2021-07-08 [PMID: 36223864]
• Lee T, Kim KS, Na K Intracellular pH-Regulating Nanoparticles to Improve Anticancer Drug Efficacy for Cancer Treatment Biomacromolecules 2022-10-12 [PMID: 36223489] (WB)
• Wu CK, Wei MT, Wu HC et al. BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation Scientific reports 2022-09-29 [PMID: 36175474]
• Youssef ME, Abdel-Reheim MA, Morsy MA et al. Ameliorative Effect of Dabigatran on CFA-Induced Rheumatoid Arthritis via Modulating Kallikrein-Kinin System in Rats International Journal of Molecular Sciences 2022-09-07 [PMID: 36142208] (WB)
• Zhao S, Li S, Yang J et al. GM-CSF-mediated inducement of bone marrow MDSCs by TSA and effect on survival of graft in mice European journal of medical research 2022-08-29 [PMID: 36031660] (WB, Mouse)
• Ollonen T, Kurkela M, Laitakari A et al. Activation of the hypoxia response protects mice from amyloid-beta accumulation Cellular and molecular life sciences : CMLS 2022-07-19 [PMID: 35852609] (WB, Mouse)
  
  Details:
  1:5000 Dilution
• Zhu K, Sun S, Guo F, Gao L Impaired Fanconi anemia pathway causes DNA hypomethylation in human angiosarcomas Human cell 2022-07-11 [PMID: 35817884] (WB)
• Martin CE, Murray AS, Mackinder JR et al. TMPRSS13 zymogen activation, surface localization, and shedding is regulated by proteolytic cleavage within the non-catalytic stem region Biological chemistry 2022-07-08 [PMID: 35796294]
• Tapio J, Halmetoja R, Dimova E et al. Contribution of HIF-P4H isoenzyme inhibition to metabolism indicates major beneficial effects being conveyed by HIF-P4H-2 antagonism Journal of Biological Chemistry 2022-07-01 [PMID: 35787374] (WB, Mouse)
• Caccuri F, Messali S, Bortolotti D et al. Competition for dominance within replicating quasispecies during prolonged SARS-CoV-2 infection in an immunocompromised host Virus Evolution 2022-06-14 [PMID: 35706980] (B/N, WB, IP)
• Luchtel RA, Zhao Y, Aggarwal RK et al. ETS1 is a novel transcriptional regulator of adult T-cell leukemia/lymphoma of North American descent Blood advances 2022-06-08 [PMID: 35675522] (WB, Human)
• Smith SS, Chu D, Qu T et al. Species-specific sensitivity to TGF? signaling and changes to the Mmp13 promoter underlie avian jaw development and evolution eLife 2022-06-06 [PMID: 35666955] (WB)
• Patel S, Kumar S, Baldan S et al. Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2alpha via the Hsp70-Bag3 module iScience 2022-04-01 [PMID: 35573186] (WB, Human)
• Yang S, Chen Z, Fan D et al. MiR-182-5p and miR-96-5p increased hepatocellular carcinoma cell mobility, proliferation and cisplatin resistance partially by targeting RND3 Am. J. Physiol. Renal Physiol. 2018-10-10 [PMID: 35547072] (WB, Human)
• Esposito F, Lyubenova H, Tornabene P et al. Liver gene therapy with intein-mediated F8 trans-splicing corrects mouse haemophilia A EMBO molecular medicine 2022-05-02 [PMID: 35491676] (WB, Human)
• Herre C, Nshdejan A, Klopfleisch R et al. Expression of vimentin, TPI and MAT2A in human dermal microvascular endothelial cells during angiogenesis in vitro PloS one 2022-04-28 [PMID: 35482724] (WB, Human)
• Chen IC, Liu YC, Wu YH et al. Proteasome Inhibitors Decrease the Viability of Pulmonary Arterial Smooth Muscle Cells by Restoring Mitofusin-2 Expression under Hypoxic Conditions Biomedicines 2022-04-09 [PMID: 35453623] (WB, Human)
• Giri R, Hoedt EC, Khushi S et al. Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation Cell reports [PMID: 35417687]
• Immonen A, Haapasaari K, Skarp S et al. NRF3 Decreases during Melanoma Carcinogenesis and Is an Independent Prognostic Marker in Melanoma Oxidative Medicine and Cellular Longevity 2022-03-26 [PMID: 35378827] (WB, Human)
• Bhoopathi, P;Pradhan, AK;Kumar, A;Maji, S;Mannangatti, P;Deng, X;Bandyopadhyay, D;Sarkar, D;Wang, XY;Landry, JW;Das, SK;Emdad, L;Fisher, PB; Conversion of a Non-Cancer-Selective Promoter into a Cancer-Selective Promoter Cancers [PMID: 35326649] (Human)
• Shigeta S, Watanabe Y, Suzuki F et al. MicroRNA-152 Regulates Endometrial Serous Carcinoma Cell Motility by Suppressing Matrix Metalloproteinase 10 Expression The Tohoku journal of experimental medicine 2022-03-01 [PMID: 35314531] (WB, Human)
• Xu J, Xu L, Sui P et al. Excess neuropeptides in lung signal through endothelial cells to impair gas exchange Developmental cell 2022-03-11 [PMID: 35303432]
• Karim S, Burzangi AS, Ahmad A Et al. PI3K-AKT Pathway Modulation by Thymoquinone Limits Tumor Growth and Glycolytic Metabolism in Colorectal Cancer Int J Mol Sci 2022-02-26 [PMID: 35216429] (WB, Human)
  
  Details:
  Citation using the HRP version of this antibody.
• Laoukili J, Constantinides A, Wassenaar ECE et al. Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity British journal of cancer 2022-02-22 [PMID: 35194192] (WB, Human)
• Rogers MA, Atkins SK, Zheng KH et al. Lipoprotein(a) Induces Vesicular Cardiovascular Calcification Revealed With Single-Extracellular Vesicle Analysis Frontiers in Cardiovascular Medicine 2022-01-28 [PMID: 35155626] (B/N, WB)
• Byts N, Sharma S, Malm T et al. Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation The Journal of biological chemistry 2022-02-10 [PMID: 35151685] (WB, Mouse)
• Skovso S, Panzhinskiy E, Kolic J et al. Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance Nature communications 2022-02-08 [PMID: 35136059] (WB, Mouse)
• Rudalska R, Harbig J, Snaebjornsson M et al. LXR alpha activation and Raf inhibition trigger lethal lipotoxicity in liver cancer Nature Cancer 2021-02-01 [PMID: 35122079]
• Rudalska R, Harbig J, Snaebjornsson M et al. LXR alpha activation and Raf inhibition trigger lethal lipotoxicity in liver cancer Nat Cancer 2022-02-05 [PMID: 35122079]
• Chen K, Chen C, Chen C et al. Bicalutamide Exhibits Potential to Damage Kidney via Destroying Complex I and Affecting Mitochondrial Dynamics Journal of Clinical Medicine 2021-12-27 [PMID: 35011880] (WB, Rat)
• Lin CH, Liao CC, Wang SY et al. Comparative O-GlcNAc Proteomic Analysis Reveals a Role of O-GlcNAcylated SAM68 in Lung Cancer Aggressiveness Cancers 2022-01-04 [PMID: 35008409] (WB)
• So Young Kim , Supyong Hwang , Lee B et al. Inhibition of histone demethylase KDM4 by ML324 induces apoptosis through the unfolded protein response and Bim upregulation in hepatocellular carcinoma cells Chemico-Biological Interactions 2022-01-01 [PMID: 34999051] (WB, Human)
• Li R, Zhang Y, Garg A et al. E3 ubiquitin ligase FBXW7 balances airway cell fates Developmental Biology 2022-03-01 [PMID: 34998785] (WB, Mouse)
• Cruz AM, Partridge KM, Malekizadeh Y et al. Brain Permeable AMP-Activated Protein Kinase Activator R481 Raises Glycaemia by Autonomic Nervous System Activation and Amplifies the Counterregulatory Response to Hypoglycaemia in Rats Front Endocrinol (Lausanne) 2021-12-17 [PMID: 34975743] (WB)
• Chen Y, Le P, Tzeng T Et al. Graptopetalum paraguayense Extract Ameliorates Proteotoxicity in Aging and Age-Related Diseases in Model Systems Nutrients 2021-11-29 [PMID: 34959868] (WB, Human)
• Chung NH, Chen YC, Yang SJ et al. Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein Vaccine 2021-12-17 [PMID: 34952759] (WB, Mouse)
• Pagano A, Breuzard G, Parat F Et al. Tau Regulates Glioblastoma Progression, 3D Cell Organization, Growth and Migration via the PI3K-AKT Axis Cancers 2021-11-19 [PMID: 34830972] (IHC-Fr, WB, Human)
• McCorkell KA, Jayachandran N, Cully MD Et al. Lymph node formation and B cell homeostasis require IKK-alpha in distinct endothelial cell-derived compartments Proceedings of the National Academy of Sciences of the United States of America 2021-11-30 [PMID: 34810256]
• Wang K, Chen PN, Chien HW Et al. Demethoxycurcumin inhibits the cell migration and MMP-2 expression in human retinal pigment epithelial cells by targeting the STAT-3 pathway Experimental eye research 2021-11-15 [PMID: 34793827] (WB, Human)
• Tornabene P, Trapani I, Centrulo M Et al. Inclusion of a degron reduces levelsof undesired inteins after AAV-mediated proteintrans-splicing in the retina Molecular Therapy - Methods & Clinical Development 2021-12-01 [PMID: 34786437] (WB, Mouse, Porcine)
• Liao GR, Tseng YY, Tseng CY Et al. The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection FEBS letters 2021-11-14 [PMID: 34778960]
• Wang Y, Sun L, Wang L Et al. PUM1 modulates trophoblast cell proliferation and migration through LRP6 Biochemistry and cell biology = Biochimie et biologie cellulaire 2021-12-01 [PMID: 34734756]
• Mehanna ET, Khalaf SS, Mesbah NM Et al. Anti-oxidant, anti-apoptotic, and mitochondrial regulatory effects of selenium nanoparticles against vancomycin induced nephrotoxicity in experimental rats Life sciences 2021-10-26 [PMID: 34715137] (WB, Rat)
• Sevilleja-Ortiz A, El Assar M, GarcIa-Rojo E Et al. Ageing-induced hypercontractility is related to functional enhancement of STIM/Orai and upregulation of Orai 3 in rat and human penile tissue Mech Ageing Dev 2021-10-26 [PMID: 34699858] (WB, Rat, Human)
  
  Details:
  Citation using the HRP version of this antibody.
• Chiu H, Chiu HP, Yu HP Et al. Zinc finger protein ZFP36L1 inhibits flavivirus infection by both 5'-3' XRN1 and 3'-5' RNA-exosome RNA decay pathways Journal of virology 2021-10-13 [PMID: 34643435]
• Hsu CH, Liu IF, Kuo HF et al. miR-29a-3p/THBS2 Axis Regulates PAH-Induced Cardiac Fibrosis International Journal of Molecular Sciences 2021-09-30 [PMID: 34638915] (WB)
• Alam S, Mohammad T, Padder RA Et al. Thymoquinone and quercetin induce enhanced apoptosis in non-small cell lung cancer in combination through the Bax/Bcl2 cascade Journal of cellular biochemistry 2021-10-12 [PMID: 34636440]
• Yoon H, Triplet EM, Simon WL Et al. Blocking Kallikrein 6 promotes developmental myelination Glia 2021-10-09 [PMID: 34626143]
• Chiang MK, Hsiao PY, Liu YY Et al. Two ST11 Klebsiella pneumoniae strains exacerbate colorectal tumorigenesis in a colitis-associated mouse model Gut microbes 2021-10-04 [PMID: 34606408] (WB, Mouse)
• Kuraoka S, Higashi H, Yanagihara Y et al. A Novel Spectral Annotation Strategy Streamlines Reporting of mono-ADP-ribosylated Peptides Derived from Mouse Liver and Spleen in Response to IFN- gamma Molecular & cellular proteomics : MCP 2021-09-27 [PMID: 34592425] (WB)
• Carlet M, Voelse K, Vergalli J et al. In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets Nat Commun 2021-09-28 [PMID: 34580292]
• Martin CE, Murray AS, Sala-Hamrick KE et al. Post-translational modifications of serine protease TMPRSS13 regulate zymogen activation, proteolytic activity, and cell surface localization The Journal of biological chemistry 2021-09-22 [PMID: 34562451] (WB, Human)
• Wu MT, Ye WT, Wang YC et al. MTHFR Knockdown Assists Cell Defense against Folate Depletion Induced Chromosome Segregation and Uracil Misincorporation in DNA International Journal of Molecular Sciences 2021-08-30 [PMID: 34502300] (WB)
• Wang HI, Chuang ZS, Kao YT Et al. Small Structural Proteins E and M Render the SARS-CoV-2 Pseudovirus More Infectious and Reveal the Phenotype of Natural Viral Variants International journal of molecular sciences 2021-08-23 [PMID: 34445789]
• Cheng CY, Chiang SY, Kao ST, Huang SC Alpinia oxyphylla Miq extract reduces cerebral infarction by downregulating JNK-mediated TLR4/T3JAM- and ASK1-related inflammatory signaling in the acute phase of transient focal cerebral ischemia in rats Chinese medicine 2021-08-21 [PMID: 34419138] (WB, Rat)
• Lamprou I, Tsolou A, Kakouratos C Et al. Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine Medical oncology (Northwood, London, England) 2021-08-19 [PMID: 34410522] (WB, Human)
• Gagnon J, Caron V, Gyenizse L, Tremblay A Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021-09-01 [PMID: 34383980]
• Beckermann Tm, Luo W, Wilson Cm Et Al. Cognate restriction of transposition by piggyBac-like proteins Nucleic acids research 2021-07-07 [PMID: 34232995] (WB)
• Hsieh MC, Lo YS, Chuang YC et al. Dehydrocrenatidine extracted from Picrasma quassioides induces the apoptosis of nasopharyngeal carcinoma cells through the JNK and ERK signaling pathways Oncology reports 2021-08-01 [PMID: 34165177] (WB, Human)
• Oyama Y, Shigeta S, Tokunaga H et al. CHD4 regulates platinum sensitivity through MDR1 expression in ovarian cancer: A potential role of CHD4 inhibition as a combination therapy with platinum agents PloS one 2021-06-23 [PMID: 34161330] (WB, Human)
• Liu WH, VOlse K, Senft D, Jeremias I A reporter system for enriching CRISPR/Cas9 knockout cells in technically challenging settings like patient models Scientific reports 2021-06-16 [PMID: 34135367] (FLOW, Human)
• Cheng CY, Huang HC, Kao ST, Lee YC Angelica sinensis extract promotes neuronal survival by enhancing p38 MAPK-mediated hippocampal neurogenesis and dendritic growth in the chronic phase of transient global cerebral ischemia in rats Journal of ethnopharmacology 2021-06-04 [PMID: 34090910]
• Lee Y, Huang H, Kao S, Cheng C Angelica Sinensis Extract Protects Against Memory Deficits by Promoting P38 MAPK mediated Hippocampal Neurogenesis and Neuronal Survival in the Chronic Phase of Transient Global Cerebral Ischemia in Rats Research Square 2020-09-17 [PMID: 34090910] (Rat)
• Chuang Y, Hsieh M, Lin C et al. Pinosylvin inhibits migration and invasion of nasopharyngeal carcinoma cancer cells via regulation of epithelial mesenchymal transition and inhibition of MMP 2 Oncology Reports 2021-05-27 [PMID: 34080661] (WB, Human)
• Hosseini-Farahabadi S, Baradaran-Heravi A, Zimmerman C et al. Small molecule Y-320 stimulates ribosome biogenesis, protein synthesis, and aminoglycoside-induced premature termination codon readthrough PLoS biology 2021-05-01 [PMID: 33939688] (WB, Human)
• Liao GR, Tseng YY, Tseng CY et al. K160 in the RNA-binding domain of the orf virus virulence factor OV20.0 is critical for its functions in counteracting host antiviral defense FEBS letters 2021-04-28 [PMID: 33909294]
• Padder RA, Bhat ZI, Ahmad Z et al. DRP1 Promotes BRAF(V600E)-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer Frontiers in Oncology 2021-03-02 [PMID: 33738242] (WB)
• Chang CW, Chiu CH, Lin MH et al. GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression EJNMMI research 2021-03-16 [PMID: 33725191] (WB, Mouse)
• Wu YH, Yang Y, Chen CH et al. Aerobic glycolysis supports hepatitis B virus protein synthesis through interaction between viral surface antigen and pyruvate kinase isoform M2 PLoS pathogens 2021-03-01 [PMID: 33720996] (WB, Human)
• Bhoopathi, P, Pradhan, A K Et al. Theranostic Tripartite Cancer Terminator Virus for Cancer Therapy and Imaging. Cancers (Basel) 2021-02-18 [PMID: 33670594] (WB, Human)
• Kang M, Thalji G, Huang CC et al. Macrophage Control of Incipient Bone Formation in Diabetic Mice Frontiers in Cell and Developmental Biology 2021-01-25 [PMID: 33569378]
• Alicea GM Metabolic Consequences of an Aging Microenvironment in Melanoma Thesis 2020-01-01 (WB, Human, Mouse)
• Triplet EM, Kim HN, Yoon H et al. The thrombin receptor links brain derived neurotrophic factor to neuron cholesterol production, resiliency and repair after spinal cord injury Neurobiology of disease 2021-02-05 [PMID: 33549720] (WB, Mouse)
• Morton RE, Mihna D, Liu Y The lipid substrate preference of CETP controls the biochemical properties of HDL in fat/cholesterol-fed hamsters Journal of lipid research 2021-01-27 [PMID: 33515552] (WB)
• Cai C, Tahiri H, Fortin C, et al. Lymphocytic microparticles suppress retinal angiogenesis via targeting Müller cells in the ischemic retinopathy mouse model Experimental cell research 2021-02-15 [PMID: 33434529] (WB, Rat)
• Tsochantaridis I, Roupas A, Voulgaridou GP, et al. Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell Morphology, Proliferation, Migration and Chemosensitivity in Human Colorectal Adenocarcinoma Cells Biomedicines 2021-01-06 [PMID: 33419031] (WB, Human)
• Gul HF, Ilhan N, Ilhan N et al. The Combined Effect of Pomegranate Extract and Tangeretin on the DMBA-induced Breast Cancer Model The Journal of nutritional biochemistry 2020-12-13 [PMID: 33326843] (WB, Rat)
• Galli A, Marciani P, Marku A et al. Verbascoside Protects Pancreatic beta -Cells against ER-Stress Biomedicines 2020-12-08 [PMID: 33302345] (WB, Mouse)
• Byts N, Sharma S, Laurila J et al. Transmembrane Prolyl 4-Hydroxylase Is a Novel Regulator of Calcium Signaling in Astrocytes eNeuro 2020-12-08 [PMID: 33298456]
• Lee YC, Kao ST, Cheng CY Acorus tatarinowii Schott extract reduces cerebral edema caused by ischemia-reperfusion injury in rats: involvement in regulation of astrocytic NKCC1/AQP4 and JNK/iNOS-mediated signaling BMC complementary medicine and therapies 2020-12-09 [PMID: 33298024] (Rat)
• Chen LY, Huang CN, Liao CK et al. Effects of Rutin on Wound Healing in Hyperglycemic Rats Antioxidants (Basel) 2020-11-13 [PMID: 33202817] (WB)
• Chao CT, Yeh HY, Tsai YT et al. Astaxanthin Counteracts Vascular Calcification In Vitro Through an Early Up-Regulation of SOD2 Based on a Transcriptomic Approach Int J Mol Sci 2020-11-12 [PMID: 33198315] (WB, Rat)
• Fenzl A, Kulterer OC, Spirk K et al. Intact vitamin A transport is critical for cold-mediated adipose tissue browning and thermogenesis Mol Metab 2020-09-26 [PMID: 32992038] (WB, Mouse)
• Liu WH, Mrozek-Gorska P, Wirth AK et al. Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL Biomarker research 2020-09-16 [PMID: 32944247] (WB)
• Zou Y, Henry WS, Ricq EL et al. Plasticity of ether lipids promotes ferroptosis susceptibility and evasion Nature 2020-09-01 [PMID: 32939090]
• Rogers MA, Buffolo F, Schlotter F et al. Annexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis Science advances 2020-09-01 [PMID: 32938681] (WB, Human)
• Chu D, Nguyen A, Smith S et al. Stable integration of an optimized inducible promoter system enables spatiotemporal control of gene expression throughout avian development Biol Open 2020-09-12 [PMID: 32917762]
• Giatromanolaki A, Kouroupi M, Pouliliou S et al. Ectonucleotidase CD73 and CD39 expression in non-small cell lung cancer relates to hypoxia and immunosuppressive pathways Life Sci. 2020-09-06 [PMID: 32898522] (WB, Human)
• Maffioli E, Galli A, Nonnis S et al. Proteomic Analysis Reveals a Mitochondrial Remodeling of ?TC3 Cells in Response to Nanotopography Frontiers in Cell and Developmental Biology 2020-07-29 [PMID: 32850772] (B/N, WB)
• Gao N, Zhao K, Cao Y et al. A role of lamin A/C in preventing neuromuscular junction decline in mice J. Neurosci. 2020-08-17 [PMID: 32817327] (WB)
• Varela FA, Foust VL, Hyland TE et al. TMPRSS13 promotes cell survival, invasion, and resistance to drug-induced apoptosis in colorectal cancer Sci Rep 2020-08-17 [PMID: 32807808] (WB, Mouse)
• Park HJ, Jo DS, Choi DS et al. Ursolic acid inhibits pigmentation by increasing melanosomal autophagy in B16F1 cells Biochem. Biophys. Res. Commun. 2020-08-10 [PMID: 32792197] (WB, Mouse)
• Liu J, Zhu C, Zhang L et al. MicroRNA-1469-5p promotes the invasion and proliferation of pancreatic cancer cells via direct regulating the NDRG1/NF-kappa B/E-cadherin axis Hum. Cell 2020-08-05 [PMID: 32757096]
• Romeo MA, Gilardini Montani MS, Benedetti R et al. STAT3 and mutp53 Engage a Positive Feedback Loop Involving HSP90 and the Mevalonate Pathway Frontiers in Oncology 2020-07-10 [PMID: 32754441]
• Lee JY, Fan CC, Chou NL et al. PHRF1 promotes migration and invasion by modulating ZEB1 expression PLoS ONE 2020-07-30 [PMID: 32730336] (IHC-P, Human)
• Cinque L, De Leonibus C, Iavazzo M et al. MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B EMBO J. 2020-09-01 [PMID: 32716134] (WB, Mouse)
• Botezelli JD, Overby P, Lindo L et al. Adipocyte depot-specific up-regulation of uncoupling protein 1 or mitochondrial oxidative complex proteins are early consequences of genetic insulin reduction in mice Am J Physiol Endocrinol Metab 2020-07-28 [PMID: 32715748]
• La Fuente JM, Sevilleja-Ortiz A, Garcia-Rojo E et al. Erectile dysfunction is associated with defective L-cysteine/hydrogen sulfide pathway in human corpus cavernosum and penile arteries Eur. J. Pharmacol. 2020-07-23 [PMID: 32712093] (WB, Human)
  
  Details:
  Citation using the HRP format of this antibody.
• Hwang S, Kim S, Kim K et al. Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein BMB Reports 2020-11-30 [PMID: 32684241] (WB)
• Karbowski, C, Goldstein, R Et al. Nonclinical Safety Assessment of AMG 553, an Investigational Chimeric Antigen Receptor T-Cell Therapy for the Treatment of Acute Myeloid Leukemia. Toxicol Sci 2020-09-01 [PMID: 32589753] (IF/IHC, Human)
• Chi TH, Hsieh BY, Liang PS et al. Expression and Functional Study of Single Mutations of Carbonic Anhydrase 8 in Neuronal Cells Cell. Mol. Neurobiol. 2020-06-24 [PMID: 32583043]
• Beauvarlet J, Nath Das R, Alvarez-Valadez K et al. Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells Cancers (Basel) 2020-06-18 [PMID: 32570977]
• Khodja Y, Samuels ME Ethanol-mediated upregulation of APOA1 gene expression in HepG2 cells is independent of de novo lipid biosynthesis Lipids Health Dis 2020-06-20 [PMID: 32563265] (WB, Human)
• Wu CL, Chang CC, Yang TH et al. Tubular transcriptional co-activator with PDZ-binding motif protects against ischemic acute kidney injury Clin. Sci. 2020-07-17 [PMID: 32558891] (Human, Mouse)
• Hsieh M, Hsieh M, Lo Y et al. Modulating effect of Coronarin D in 5-fluorouracil resistance human oral cancer cell lines induced apoptosis and cell cycle arrest through JNK1/2 signaling pathway Biomedicine & Pharmacotherapy 2020-08-01 [PMID: 32502840] (WB, Human)
• Alicea GM, Rebecca VW, Goldman AR et al. Changes in Aged Fibroblast Lipid Metabolism Induce Age-dependent Melanoma Cell Resistance to Targeted Therapy Via the Fatty Acid Transporter FATP2 Cancer Discov 2020-06-04 [PMID: 32499221]
• Marshall J, Courage E, Elliott R et al. THP-1 Macrophage Cholesterol Efflux Is Impaired by Palmitoleate Through Akt Activation PLoS One. 2020-05-21 [PMID: 32437392] (WB, Human)
• Oishi N, Hundal T, Phillips JL et al. Molecular profiling reveals a hypoxia signature in breast implant-associated anaplastic large cell lymphoma Haematologica 2020-05-15 [PMID: 32414854] (WB, Human)
• Chang Y, Ko B, Ju J et al SARS Unique Domain (SUD) of Severe Acute Respiratory Syndrome Coronavirus Induces NLRP3 Inflammasome-Dependent CXCL10-Mediated Pulmonary Inflammation. 2020-04-30 [PMID: 32365944] (WB, Cytometric Bead Assay Standard, Human)
• Jin Y, Shen Y, Su X et al. The Small GTPases Rab27b Regulates Mitochondrial Fatty Acid Oxidative Metabolism of Cardiac Mesenchymal Stem Cells Front Cell Dev Biol 2020-04-15 [PMID: 32351955] (WB, Mouse)
• Barbier V, Erbani J, Fiveash C et al. Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance Nat Commun 2020-04-27 [PMID: 32341362] (WB, Mouse)
• Li R, Li X, Hagood J et al. Myofibroblast contraction is essential for generating and regenerating the gas-exchange surface J. Clin. Invest. 2020-04-27 [PMID: 32338642] (WB, Mouse)
• Lieberman O J, Cartocci V et al. mTOR Suppresses Macroautophagy During Striatal Postnatal Development and Is Hyperactive in Mouse Models of Autism Spectrum Disorders. Front Cell Neurosci 2020-04-17 [PMID: 32296308] (WB, Mouse)
• Romeo MA, Gilardini Montani MS, Benedetti R et al. PBA Preferentially Impairs Cell Survival of Glioblastomas Carrying mutp53 by Reducing Its Expression Level, Stabilizing wtp53, Downregulating the Mevalonate Kinase and Dysregulating UPR Biomolecules 2020-04-10 [PMID: 32290231]
• Murthi P, Rajaraman G et al. Decreased Placental FPR2 in Early Pregnancies That Later Developed Small-For-Gestation Age: A Potential Role of FPR2 in the Regulation of Epithelial-Mesenchymal Transition. Cells 2020-10-04 [PMID: 32290034] (WB, Human)
• Pei X, Kim H, Lee M et al. Local delivery of cardiac stem cells overexpressing HIF-1 alpha promotes angiogenesis and muscular tissue repair in a hind limb ischemia model J Control Release 2020-03-16 [PMID: 32194175] (WB, Rat)
• Ortolan L, Sercundes M, Moura G et al. Critical contribution of endothelial protein C receptor in experimental malaria-associated acute respiratory distress syndrome bioRxiv 2018-06-15 [PMID: 31871954] (WB, Mouse)
• Oh S, Do M, Shin J et al. A Combination of Natural Products, BenPros (Green Tea Extract, Soybean Extract and Camellia Japonica Oil), Ameliorates Benign Prostatic Hyperplasia Applied Sciences 2022-06-16
• Lin Jh, Chen Sy, Lu Cc et Al. Ursolic acid promotes apoptosis, autophagy, and chemosensitivity in gemcitabine-resistant human pancreatic cancer cells Phytother Res 2020-03-17 [PMID: 32185829] (WB)
• Trent B, Liang Y, Xing Y et al. Polarized Lung Inflammation and Tie2/Angiopoietin-Mediated Endothelial Dysfunction during Severe Orientia tsutsugamushi Infection BioRxi 2019-08-02 [PMID: 32119672] (WB, Mouse, Human)
• Laitakari A, Huttunen R, Kuvaja P et al. Systemic long-term inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 ameliorates aging-induced changes in mice without affecting their life span FASEB J. 2020-02-25 [PMID: 32100354] (WB, Mouse)
• Chen YJ, Tsai CY, Cheng YM et al. Impacts of Intralipid on Nanodrug Abraxane Therapy and on the Innate Immune System Sci Rep 2020-02-18 [PMID: 32071352] (WB, Mouse)
• Moretti, A, Fonteyne, L Et al. Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy. Nat Med 2020-02-01 [PMID: 31988462] (IF/IHC, Drosophila melanogaster)
• Cheng CY, Kao ST, Lee YC Angelica sinensis extract protects against ischemia-reperfusion injury in the hippocampus by activating p38 MAPK-mediated p90RSK/p-Bad and p90RSK/CREB/BDNF signaling after transient global cerebral ischemia in rats J Ethnopharmacol 2020-01-24 [PMID: 31988015] (WB, Rat)
• Giatromanolaki A, Fasoulaki V et al. CYP17A1 and Androgen-Receptor Expression in Prostate Carcinoma Tissues and Cancer Cell Lines. Curr Urol 2019-01-11 [PMID: 31933595] (WB, Human)
• Biswas L, Zeng Z, Graham A, Shu X Gypenosides mediate cholesterol efflux and suppress oxidized LDL induced inflammation in retinal pigment epithelium cells Exp. Eye Res. 2020-01-10 [PMID: 31931003] (WB, Human)
• Lieberman OJ, Frier MD, McGuirt AF et al. Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy Elife 2020-01-08 [PMID: 31913125]
• Cho S, Chae J, Shin H, et al. Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation Translational Oncology 2019-12-31 [PMID: 31901552] (WB, Mouse)
• Alhakamy NA, Md S Repurposing Itraconazole Loaded PLGA Nanoparticles for Improved Antitumor Efficacy in Non-Small Cell Lung Cancers Pharmaceutics 2019-12-16 [PMID: 31888155] (WB, Human)
• Dos Santos Ortolan L, Sercundes MK, Moura GC et al. Endothelial Protein C Receptor Could Contribute to Experimental Malaria-Associated Acute Respiratory Distress Syndrome J Immunol Res 2019-12-04 [PMID: 31871954] (WB, Mouse)
• Rogers MA, Chen J, Nallamshetty S et al. Retinoids Repress Human Cardiovascular Cell Calcification With Evidence for Distinct Selective Retinoid Modulator Effects Arterioscler. Thromb. Vasc. Biol. 2019-12-19 [PMID: 31852220] (WB, Human)
• Langley MR, Yoon H, Kim HN, et al. High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system Biochim Biophys Acta Mol Basis Dis 2019-12-06 [PMID: 31816440] (WB, Mouse)
• Lima FA, Barateiro A, Dombrowski JG Plasmodium falciparum infection dysregulates placental autophagy PLoS ONE 2019-12-05 [PMID: 31805150] (WB, Human)
• Su X, Jin Y, Shen Y et al. RNAase III-Type Enzyme Dicer Regulates Mitochondrial Fatty Acid Oxidative Metabolism in Cardiac Mesenchymal Stem Cells Int J Mol Sci 2019-11-07 [PMID: 31703292] (WB, KO, Human, Mouse)
• Lin M C, Shen C H et al. Inhibition of human lung adenocarcinoma growth and metastasis by JC polyomavirus-like particles packaged with an SP-B promoter-driven CD59-specific shRNA. Clin Sci (Lond) 2019-11-15 [PMID: 31693732] (WB, Human)
• H�m�l�inen M, Teppo HR, Skarp S et al. NRF1 and NRF2 mRNA and Protein Expression Decrease Early during Melanoma Carcinogenesis: An Insight into Survival and MicroRNAs Oxidative Medicine and Cellular Longevity 2019-09-04 [PMID: 31687076]
• Arima N, Sasaki Y, Lee LH et al. Multiorgan Systems Study Reveals Igfbp7 as a Suppressor of Gluconeogenesis after Gastric Bypass Surgery J. Proteome Res. 2019-11-18 [PMID: 31661273] (Mouse)
• Mahmoudi S, Mancini E, Xu L et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing Nature 2019-10-01 [PMID: 31645721] (WB, Mouse)
• Xu Y, Xu Y, Zhu Y et al. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis Mol. Ther. 2019-09-12 [PMID: 31604677]
• Hughes BA, Crofton EJ, O'Buckley TK et al. Chronic ethanol exposure alters prelimbic prefrontal cortical Fast-Spiking and Martinotti interneuron function with differential sex specificity in rat brain Neuropharmacology 2019-10-04 [PMID: 31589884] (WB, Rat)
• Herroon MK, Diedrich JD, Rajagurubandara E et al. Prostate tumor cell-derived IL-1beta induces an inflammatory phenotype in bone marrow adipocytes and reduces sensitivity to docetaxel via lipolysis-dependent mechanisms Mol. Cancer Res. 2019-09-27 [PMID: 31562254] (WB, Mouse, Human)
• Aladaileh SH, Hussein OE, Abukhalil MH et al. Formononetin Upregulates Nrf2/HO-1 Signaling and Prevents Oxidative Stress, Inflammation, and Kidney Injury in Methotrexate-Induced Rats Antioxidants (Basel) 2019-09-26 [PMID: 31561418] (WB, Rat)
• Xing G, Jing H, Zhang L et al. A mechanism in Agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome Elife 2019-09-24 [PMID: 31549961] (WB, Mouse)
• Vande Walle L, Stowe IB, SAcha P et al. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition PLoS Biol. 2019-09-01 [PMID: 31525186] (WB, Mouse)
• Holdgaard SG, Cianfanelli V, Pupo E et al. Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites Nat Commun [PMID: 31519908] (WB)
• Su SC, Hung YJ, Huang CL et al. Cilostazol inhibits hyperglucose-induced vascular smooth muscle cell dysfunction by modulating the RAGE/ERK/NF-kappaB signaling pathways J. Biomed. Sci. 2019-09-06 [PMID: 31492153] (WB, KD, Mouse, Rat)
• Lo C H, Lin I H et al. Phosphorylation of CEP83 by TTBK2 is necessary for cilia initiation. J Cell Biol 2019-07-10 [PMID: 31455668] (WB, Human)
• Zhou TE, Zhu T, Rivera JC et al. The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity Am J Pathol. 2019-08-17 [PMID: 31430465] (WB, WB, Rat)
• Li MY, Peng WH, Wu CH et al. PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization Oncogene 2019-08-12 [PMID: 31406243] (KD)
• Stroik S, Kurtz K, Hendrickson EA CtIP is essential for telomere replication Nucleic Acids Res. 2019-08-05 [PMID: 31378812] (WB, Human)
• Hao C, Liu G, Tian G Autophagy inhibition of cancer stem cells promotes the efficacy of cisplatin against non-small cell lung carcinoma Ther Adv Respir Dis 2019-08-02 [PMID: 31368411] (WB, Human)
• Hayward D, Kouznetsova VL, Pierson HE et al. ANKRD9 is a metabolically-controlled regulator of IMPDH2 abundance and macro-assembly J. Biol. Chem. 2019-07-23 [PMID: 31337707] (WB, Human)
• Halim H, Pinkaew D, et al. Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel. PLoS One 2019-06-27 [PMID: 31242230] (WB, Mouse)
• Woodard L E, Welch R C et al. Metabolic consequences of cystinuria. BMC Nephrol 2019-06-20 [PMID: 31221135] (WB, Mouse)
• Tsolou A, Lamprou I, Fortosi AO et al. Stemness' and 'senescence' related escape pathways are dose dependent in lung cancer cells surviving post irradiation Life Sci. 2019-06-12 [PMID: 31201845] (WB, Human)
• Wangsa D, Braun R, Stuelten CH et al. Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells Neoplasia 2019-07-01 [PMID: 31174021] (WB, Human)
• Bai X, Ihara E, Otsuka Y et al. Mutations in KARS cause a severe neurological and neurosensory disease with optic neuropathy Hum. Mutat. 2019-05-22 [PMID: 31116475] (WB, Human)
• Miktosz A, tukaszuk B, Baranowski M et al. Nerve regeneration in rat peripheral nerve allografts: Evaluation of cold-inducible RNA-binding protein in nerve storage and regeneration J. Comp. Neurol. 2019-05-22 [PMID: 31116410]
• Saporiti F, Piacentini L, Alfieri V Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration Cell. Physiol. Biochem. 2019-04-11 [PMID: 31050282] (WB, Human)
• Sakai, S;Ohhata, T;Kitagawa, K;Uchida, C;Aoshima, T;Niida, H;Suzuki, T;Inoue, Y;Miyazawa, K;Kitagawa, M; Long noncoding RNA ELIT-1 acts as a Smad3 cofactor to facilitate TGF-beta/Smad signaling and promote epithelial-mesenchymal transition Cancer Res. 2019-04-05 [PMID: 30952633] (WB, Human)
• Chiba, M;Ito, Y;Nagasawa, T; Phenethyl isothiocyanate stimulates glucose uptake through the Akt pathway in C2C12 myotubes Biosci. Biotechnol. Biochem. 2019-03-28 [PMID: 30919745] (WB, Mouse)
• Hughes BA, Bohnsack JP, O'Buckley TK et al. Chronic Ethanol Exposure and Withdrawal Impairs Synaptic GABAA Receptor-Mediated Neurotransmission in Deep Layer Prefrontal Cortex Alcohol. Clin. Exp. Res. 2019-03-12 [PMID: 30860602] (WB, Rat)
• Wu H, Ploeger JM, Kamarajugadda S, et al. Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes. Hepatol Commun. 2019-01-30 [PMID: 30859152] (WB, Mouse)
• Lee MJ, Miller Z, Park JE et al. H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth Sci Rep 2019-03-11 [PMID: 30858500] (WB, Human)
• Laitakari A, Ollonen T, Kietzmann T et al. Systemic inactivation of hypoxia-inducible factor prolyl 4-hydroxylase 2 in mice protects from alcohol-induced fatty liver disease Redox Biol 2019-02-19 [PMID: 30802717] (WB, Mouse)
• Ryzhikov M, Ehlers A, Steinberg D et al. Diurnal Rhythms Spatially and Temporally Organize Autophagy Cell Rep 2019-02-12 [PMID: 30759397] (WB, Mouse)
• Beauvarlet J, Bensadoun P, Darbo E et al. Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells Nucleic Acids Res. 2019-02-13 [PMID: 30759257] (WB, Human)
• van der Waals LM, Laoukili J, Jongen JMJ et al. Differential anti-tumour effects of MTH1 inhibitors in patient-derived 3D colorectal cancer cultures. Sci Rep 2019-01-28 [PMID: 30692572] (WB, Human)
• Zhang H, Wei Q, Xiang X et al. Semaphorin 4A acts in a feed-forward loop with NF-kB pathway to exacerbate catabolic effect of IL-1b on chondrocytes. Int. Immunopharmacol. 2019-01-24 [PMID: 30685700] (WB, Mouse)
• Mega Tiber P, Kocyigit Sevinc S, Kilinc O, Orun O Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562. Gene. 2019-04-15 [PMID: 30684525] (WB, Human)
  
  Details:
  Citation using the Azide free version of this antibody.
• Spence EF, Dube S, Uezu A et al. In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation. Nat Commun 2019-01-23 [PMID: 30674877] (WB, Human)
• Even I, Reidenbach S, Schlechter T et al. DLIC1, but not DLIC2, is upregulated in colon cancer and this contributes to proliferative overgrowth and migratory characteristics of cancer cells. FEBS J. 2019-01-18 [PMID: 30657258] (WB, Human)
• Ye R, Onodera T, Blanchard PG et al. b1 syntrophin supports autophagy initiation and protects against cerulein-induced acute pancreatitis. Am. J. Pathol. 2019-01-14 [PMID: 30653956] (WB, Mouse)
• Wang B, Pan JX, Yu H et al. Lack of myosin X enhances osteoclastogenesis and increases cell surface Unc5b in osteoclast-lineage cells. J. Bone Miner. Res. 2019-01-15 [PMID: 30645777] (WB, Mouse)
• Lee CH, Yang JR, Chen CY et al. Novel STAT3 Inhibitor LDOC1 Targets Phospho-JAK2 for Degradation by Interacting with LNX1 and Regulates the Aggressiveness of Lung Cancer. Cancers (Basel) 2019-01-09 [PMID: 30634502] (WB, Human)
• Cheng CY, Kao ST, Lee YC. Ferulic Acid Exerts Anti-apoptotic Effects against Ischemic Injury by Activating HSP70/Bcl-2- and HSP70/Autophagy-Mediated Signaling after Permanent Focal Cerebral Ischemia in Rats. Am. J. Chin. Med. 2019-01-07 [PMID: 30612456] (WB, Rat)
• Davis SM, Collier LA, Foran EA et al. Neuroprotective activity of leukemia inhibitory factor is relayed through myeloid zinc finger-1 in a rat model of stroke Metab Brain Dis. 2019-04-15 [PMID: 30612292] (WB, Rat)
  
  Details:
  Citation using the HRP form of this antibody.
• Chen JM, Yang TT, Cheng TS et al. Modified Sijunzi decoction can alleviate cisplatin-induced toxicity and prolong the survival time of cachectic mice by recovering muscle atrophy J Ethnopharmacol 2018-12-24 [PMID: 30590199] (WB, Mouse)
• Cheng C Y, Kao S T et al. Ferulic acid ameliorates cerebral infarction by activating Akt/mTOR/4E BP1/Bcl 2 anti apoptotic signaling in the penumbral cortex following permanent cerebral ischemia in rats. Mol Med Rep 2019-01-02 [PMID: 30569126] (WB, Rat)
• Oh SH, Sung YH, Kim I et al. Novel Compound Heterozygote Mutation in IL10RA in a Patient With Very Early-Onset Inflammatory Bowel Disease. Inflamm. Bowel Dis. 2018-11-21 [PMID: 30462267] (WB, Human)
• Yang CF, Gopula B, Liang JJ et al. Novel AR-12 derivatives, P12-23 and P12-34, inhibit flavivirus replication by blocking host de novo pyrimidine biosynthesis. Emerg Microbes Infect. 2018-11-21 [PMID: 30459406] (WB, Human)
• Davis SM, Collier LA, Goodwin S et al. Efficacy of Leukemia Inhibitory Factor as a Therapeutic for Permanent Large Vessel Stroke Differs among Aged Male and Female Rats. Brain Res. 2018-11-13 [PMID: 30445025] (WB, Rat)
• Harun-Or-Rashid M, Inman DM. Reduced AMPK activation and increased HCAR activation drive anti-inflammatory response and neuroprotection in glaucoma. J Neuroinflammation. 2018-11-13 [PMID: 30424795] (WB, Mouse)
• Di K, Lomeli N, Bota DA, Das BC. Magmas inhibition as a potential treatment strategy in malignant glioma. J. Neurooncol. 2018-11-09 [PMID: 30414099] (WB, Human)
• Zhang C, Lai MB, Pedler MG et al. Endothelial Cell-Specific Inactivation of TSPAN12 (Tetraspanin 12) Reveals Pathological Consequences of Barrier Defects in an Otherwise Intact Vasculature. Arterioscler. Thromb. Vasc. Biol. 2018-11-01 [PMID: 30354230] (WB, Mouse)
• Davis SM, Collier LA, Winford ED et al. Leukemia inhibitory factor modulates the peripheral immune response in a rat model of emergent large vessel occlusion. J Neuroinflammation. 2018-10-15 [PMID: 30322390] (WB, Rat)
• Halu A, Wang JG, Iwata H et al. Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation. Elife. 2018-10-10 [PMID: 30303482] (WB, Human)
• Yang C, Stueve TR, Yan C et al. Positional integration of lung adenocarcinoma susceptibility loci with primary human alveolar epithelial cell epigenomes. Epigenomics 2018-09-01 [PMID: 30212242] (WB, Human)
• Going CC, Tailor D, Kumar V et al. Quantitative Proteomic Profiling Reveals Key Pathways in the Anticancer Action of Methoxychalcone Derivatives in Triple Negative Breast Cancer. J. Proteome Res. 2018-09-20 [PMID: 30200768] (WB, Human)
• Zhao K, Shen C, Li L et al. Sarcoglycan Alpha Mitigates Neuromuscular Junction Decline in Aged Mice by Stabilizing LRP4. J. Neurosci. 2018-08-30 [PMID: 30171091] (WB, Mouse)
• Lee BL, Stowe IB, Gupta A et al. Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation J. Exp. Med. 2018-08-22 [PMID: 30135078] (WB, Mouse)
• Vicente MC, Almeida MC, Bicego KC et al. Hypercapnic and Hypoxic Respiratory Response During Wakefulness and Sleep in a Streptozotocin Model of Alzheimer's Disease in Rats J. Alzheimers Dis. 2018-08-14 [PMID: 30124447] (Rat)
• Li Z, Qian P, Shao W et al. Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion Cell Res. 2018-07-31 [PMID: 30065315] (WB, Mouse)
• Lieberman OJ, McGuirt AF, Mosharov EV et al. Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period. Neuron. 2018-07-20 [PMID: 30057204] (WB, Mouse)
• Benhadjeba S, Edjekouane L, Sauve k et al. Feedback control of the CXCR7/CXCL11 chemokine axis by estrogen receptor a in ovarian cancer. Mol Oncol. 2018-07-27 [PMID: 30051594] (WB, Human)
• Chiu HP, Chiu H, Yang CF et al. Inhibition of Japanese encephalitis virus infection by the host zinc-finger antiviral protein. PLoS Pathog. 2018-07-01 [PMID: 30016363] (WB, Human)
• Laukka T, Myllykoski M, Looper RE, Koivunen P. Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases. J. Mol. Biol. 2018-07-05 [PMID: 29981745] (WB, Human)
• Li TN, Wu YJ, Tsai HW et al. Intrahepatic HBV large surface antigen induces hepatocyte hyperploidy via failure of cytokinesis J. Pathol. 2018-06-03 [PMID: 29862509] (Human)
• Motzko-Soares ACP, Vizin RCL, Martins TMS et al. Thermoregulatory profile of neurodegeneration-induced dementia of the Alzheimer's type using intracerebroventricular streptozotocin in rats Acta Physiol (Oxf) 2018-05-02 [PMID: 29719119] (Rat)
• Zhou R, Xu T, Liu X et al. Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1b and IL-6 in rats with diabetic neuropathic pain. J Pain Res 2018-03-27 [PMID: 29628771] (WB, Rat)
• Ferriero R, Nusco E, De Cegli R et al. Pyruvate dehydrogenase complex and lactate dehydrogenase as targets for therapy of acute liver failure. J. Hepatol. 2018-03-23 [PMID: 29580866] (WB, Mouse)
• Tsai MS, Wang YH, Lai YY et al. Kaempferol protects against propacetamol-induced acute liver injury through CYP2E1 inactivation, UGT1A1 activation, and attenuation of oxidative stress, inflammation and apoptosis in mice. Toxicol. Lett. 2018-03-21 [PMID: 29574133] (Mouse)
• Marmorstein A. D, Johnson A. A, et al. Mutant Best1 Expression and Impaired Phagocytosis in an iPSC Model of Autosomal Recessive Bestrophinopathy. Sci Rep 2018-03-14 [PMID: 29540715] (SW, Human)
• Lee BL, Mirrashidi KM, Stowe IB et al. ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages. Sci Rep. 2018-02-28 [PMID: 29491424] (WB, Mouse)
• Steiner C, Gevaert T, Ganzer R, De Ridder D. Comparative immunohistochemical characterization of interstitial cells in the urinary bladder of human, guinea pig and pig. Histochem. Cell Biol. 2018-02-20 [PMID: 29464320] (Human)
• Nsende EJ Experimental Validation of Gene Expression of MYBL1, MYBL2, UBXN8, and ADRM1 Genes in Triple Negative Breast Cancer Cell Lines Thesis 2022-01-01
• Maddalena A, Dell'Aquila F, Giovannelli P et al. High-Throughput Screening Identifies Kinase Inhibitors That Increase Dual Adeno-Associated Viral Vector Transduction In Vitro and in Mouse Retina Hum. Gene Ther. 2018-08-01 [PMID: 29641320] (WB, Human)
• Ye R, Gordillo R, Shao M et al. Intracellular lipid metabolism impairs B cell compensation during diet-induced obesity J. Clin. Invest. 2018-03-01 [PMID: 29457786] (WB, Mouse)
• Kocyigit Sevinc S, Karadeniz M, Sen A et al. Biological Effects of Urtica Dioica Extract on K562 Chronic Myeloid Leukemia Cell Line SSRN Electronic Journal 2022-10-29 (WB, Human)
• Itoh S, Mizuno K, Aikawa M, Aikawa E. Dimerization of sortilin regulates its trafficking to extracellular vesicles. J. Biol. Chem. 2018-01-30 [PMID: 29382723] (Human)
• Yu X, Stallone JN, Heaps CL, Han G. The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries PLoS ONE 2018-01-23 [PMID: 29360846] (WB, Porcine)
• Maddalena A, Tornabene P, Tiberi P et al. Triple Vectors Expand AAV Transfer Capacity in the Retina Mol Ther. 2018-02-06 [PMID: 29292161] (WB, Human)
• Nag S, Resnick A. Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport. Physiol Rep 2017-12-01 [PMID: 29263117] (WB, Mouse)
• Pol A, Renkema GH, Tangerman A et al. Mutations in SELENBP1, encoding a novel human methanethiol oxidase, cause extraoral halitosis. Nat. Genet. 2018-01-01 [PMID: 29255262] (Human)
• Cree BAC, Niu J, Hoi KK et al. Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain 2017-12-13 [PMID: 29244098] (WB, Human)
• Ullah K, Rosendahl AH, Izzi V et al. Hypoxia-inducible factor prolyl-4-hydroxylase-1 is a convergent point in the reciprocal negative regulation of NF-kB and p53 signaling pathways. Sci Rep 2017-12-08 [PMID: 29222481] (WB, Mouse)
• Khan N, Muralidharan A, Smith MT. Attenuation of the Infiltration of Angiotensin II Expressing CD3+ T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia-A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT2) Receptor Antag Front Mol Neurosci. 2017-11-21 [PMID: 29200998] (WB, Rat)
• Jongen JMJ, van der Waals LM, Trumpi K et al. Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability Oncotarget. 2017-10-17 [PMID: 29156796] (WB)
• Mazzoni J, Smith JR, Shahriar S et al. The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels Neuron. 2017-11-04 [PMID: 29154126] (Mouse)
• Ge Q, Zhang H, Hou J et al. VEGF secreted by mesenchymal stem cells mediates the differentiation of endothelial progenitor cells into endothelial cells via paracrine mechanisms Mol Med Rep. 2018-01-01 [PMID: 29138837] (WB)
• El-Hassan AR, Leung V, Kharfallah F et al. Identification and characterization of a novel chemically induced allele at the planar cell polarity gene Vangl2. Mamm. Genome. 2017-10-24 [PMID: 29063958] (WB, Mouse)
• Zhao W, Pferdehirt L, Segatori L. Quantitatively predictable control of cellular protein levels through proteasomal degradation. ACS Synth Biol. 2017-10-23 [PMID: 29061039] (WB)
• Walters DK, Arendt BK, Tschumper RC et al. Characterization and use of the novel human multiple myeloma cell line MC-b11/14 to study biological consequences of CRISPR-mediated loss of immunoglobulin a heavy chain. Exp. Hematol. 2017-10-10 [PMID: 29030084] (Human)
• Jian Y, Gao W et al. Arsenic trioxide potentiates sensitivity of multiple myeloma cells to lenalidomide by upregulating cereblon expression levels. Oncol Lett 2017-01-09 [PMID: 28927072] (WB, Human)
• Yoon H, Radulovic M, Walters G et al. Protease activated receptor 2 controls myelin development, resiliency and repair Glia 2017-09-18 [PMID: 28921694] (Mouse)
• Niu J, Huang D, Zhou R et al. Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats J Neuroinflammation 2017-09-12 [PMID: 28899427] (WB, Rat)
• Nagami M, Ito Y, Nagasawa T. Phenethyl isothiocyanate protects against H2O2-induced insulin resistance in 3T3-L1 adipocytes Biosci. Biotechnol. Biochem. 2017-09-13 [PMID: 28899227] (Mouse)
• Chiu HY, Tsay YG, Hung SC. Involvement of mTOR-autophagy in the selection of primitive mesenchymal stem cells in chitosan film 3-dimensional culture Sci Rep 2017-08-31 [PMID: 28860574] (WB, Human)
• Bohnsack JP, Patel VK, Morrow AL. Ethanol exposure regulates Gabra1 expression via histone deacetylation at the promoter in cultured cortical neurons J. Pharmacol. Exp. Ther. 2017-08-10 [PMID: 28798030]
• Noutsios GT, Willis AL, Ledford JG, Chang EH. Novel role of surfactant protein A in bacterial sinusitis Int Forum Allergy Rhinol 2017-07-20 [PMID: 28727907] (Human)
• Lin NH, Messing A, Perng MD. Characterization of a panel of monoclonal antibodies recognizing specific epitopes on GFAP PLoS ONE 2017-07-12 [PMID: 28700643] (WB, Human)
• Yoon H, Walters G, Paulsen AR, Scarisbrick IA. Astrocyte heterogeneity across the brain and spinal cord occurs developmentally, in adulthood and in response to demyelination PLoS ONE 2017-07-12 [PMID: 28700615] (WB, Mouse)
• Ambroz M, Matouskova P, Skarka A et al. The Effects of Selected Sesquiterpenes from Myrica rubra Essential Oil on the Efficacy of Doxorubicin in Sensitive and Resistant Cancer Cell Lines. Molecules. 2017-06-20 [PMID: 28632185] (WB, Human)
• Chang CJ, Lu CC, Lin CS, Martel J. Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice. Int J Obes (Lond). 2018-02-01 [PMID: 28630461] (WB, Mouse)
• Hou J, Peng X et al. Mesenchymal stem cells promote endothelial progenitor cell proliferation by secreting insulin like growth factor 1. Mol Med Rep 2017-01-08 [PMID: 28627605] (WB, Mouse)
• Wu PK, Wang JY, Chen CF et al. Early Passage Mesenchymal Stem Cells Display Decreased Radiosensitivity and Increased DNA Repair Activity. Stem Cells Transl Med 2017-06-01 [PMID: 28544661] (WB, Human)
• Balbaa M, Abdulmalek SA, Khalil S. Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs. PLoS ONE 2017-05-15 [PMID: 28505155] (WB, Rat)
• Neuhaus J, Schiffer E et al. Protease Expression Levels in Prostate Cancer Tissue Can Explain Prostate Cancer-Associated Seminal Biomarkers-An Explorative Concept Study. Int J Mol Sci 2017-04-05 [PMID: 28471417] (WB, Human)
• Pettersson H, Zarnegar B, Westin A et al. SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo. Sci Rep 2017-04-24 [PMID: 28439090] (WB, Mouse)
• Wang X, Dasari S, Nowakowski GS et al. Retinoic acid receptor alpha drives cell cycle progression and is associated with increased sensitivity to retinoids in T-cell lymphoma. Oncotarget 2017-04-18 [PMID: 28412739] (WB, Human)
• Ho TJ, Lee CW, Lu ZY et al. Effects of Electroacupuncture on Methamphetamine-Induced Behavioral Changes in Mice. Evid Based Complement Alternat Med 2017-03-16 [PMID: 28400844] (WB, Mouse)
• Lee YS, Kim JY, Oh KS, Chung SW. Fatty acid-binding protein 4 regulates fatty infiltration after rotator cuff tear by hypoxia-inducible factor 1 in mice. J Cachexia Sarcopenia Muscle. 2017-04-05 [PMID: 28382782] (WB, Mouse)
• Raats DA, Frenkel N, van Schelven SJ et al. CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage. Cell Death Dis. 2017-03-16 [PMID: 28300842] (WB, Human)
• Piccolo P, Annunziata P, Soria LR et al. Downregulation of HNF-4a and defective zonation in livers expressing mutant Z a1-antitrypsin.. Hepatology. 2017-03-15 [PMID: 28295475] (IF/IHC, Mouse)
• Chen KC, Hsieh MS, Li YR et al. Study of poly-e-caprolactone membranes for pleurodesis. J. Formos. Med. Assoc. 2017-02-16 [PMID: 28215672] (WB, Rabbit)
• Bilodeau S, Caron V, Gagnon J et al. A CK2-RNF4 interplay coordinates non-canonical SUMOylation and degradation of nuclear receptor FXR J Mol Cell Biol 2017-06-01 [PMID: 28201649] (WB, Human)
• Giatromanolaki A, Liousia M, Arelaki S et al. Differential effect of hypoxia and acidity on lung cancer cell and fibroblast metabolism. Biochemistry and Cell Biology. 2017-01-24 [PMID: 28177758] (WB)
• Wang X, Boddicker RL, Dasari S et al. Expression of p63 protein in anaplastic large cell lymphoma: Implications for genetic subtyping. Hum. Pathol. 2017-01-30 [PMID: 28153507] (WB)
• Sansone C, Galasso C, Orefice I et al. The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells Sci Rep 2017-01-24 [PMID: 28117410] (WB, Human)
• Pereira ML, Ortolan LS, Sercundes MK et al. Association of Heme Oxygenase 1 with Lung Protection in Malaria-Associated ALI/ARDS Mediators Inflamm. 2016-11-14 [PMID: 27974865] (WB, Mouse)
• Abdelbaset-Ismail Ahmed, Pedziwiatr Daniel, Schneider Gabriela et al. Pituitary sex hormones enhance the pro-metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase-1 International Journal of Oncology 2017-01-01 [PMID: 27922667] (WB, Mouse)
• Lin YC, Chao TY, Yeh CT et al. Endothelial SCUBE2 Interacts With VEGFR2 and Regulates VEGF-Induced Angiogenesis. Arterioscler. Thromb. Vasc. Biol. 2016-11-10 [PMID: 27834687]
• Chen HR, Yeh YC, Liu CY et al. DDR1 promotes E-cadherin stability via inhibition of integrin-beta1-Src activation-mediated E-cadherin endocytosis. Sci Rep. 2016-11-08 [PMID: 27824116] (WB, Canine)
• Getun IV, Wu Z, Fallahi M et al. Functional Roles of Acetylated Histone Marks at Mouse Meiotic Recombination Hotspots. Mol. Cell. Biol. 2016-11-07 [PMID: 27821479] (WB, Mouse)
• Patterson B A, Matarneh S K et al. Pectoralis major muscle of turkey displays divergent function as correlated with meat quality. Poult Sci 2017-01-05 [PMID: 27816932] (WB, Turkey)
  
  Details:
  Meleagris gallopavo (Turkey)
• Iwata H, Goettsch C, Sharma A et al. PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation. Nat Commun. 2016-10-31 [PMID: 27796300] (WB, Mouse)
• Zhou TE, Rivera JC, Bhosle VK et al. Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1B. Am. J. Pathol. 2016-10-18 [PMID: 27768863] (WB)
• Di K, Lomeli N, Wood SD et al. Mitochondrial Lon is over-expressed in high-grade gliomas, and mediates hypoxic adaptation: potential role of Lon as a therapeutic target in glioma. Oncotarget. 2016-11-22 [PMID: 27764809] (WB, Human)
• Pradhan S, Mahajan D, Kaur P et al. Scriptaid overcomes hypoxia-induced cisplatin resistance in both wild-type and mutant p53 lung cancer cells. Oncotarget. 2016-11-01 [PMID: 27708247] (ICC/IF, Human)
• Hu Y, Su H, Liu C et al. DEPTOR is a direct NOTCH1 target that promotes cell proliferation and survival in T-cell leukemia. Oncogene 2016-09-05 [PMID: 27593934] (WB)
• Erdogan S, Doganlar O, Doganlar ZB et al. The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-kB signaling. Life Sci. 2016-08-25 [PMID: 27569589] (WB)
• Yoon H, Scarisbrick IA. Kallikrein-related peptidase 6 exacerbates disease in an autoimmune model of multiple sclerosis. Biol. Chem. 2016-08-17 [PMID: 27533119]
• Vanas V, Haigl B, Stockhammer V, Sutterluty-Fall H. MicroRNA-21 Increases Proliferation and Cisplatin Sensitivity of Osteosarcoma-Derived Cells. PLoS ONE. 2016-08-12 [PMID: 27513462] (WB)
• Leinonen H, Rossi M, Salo AM et al. Lack of P4H-TM in mice results in age-related retinal and renal alterations. Hum. Mol. Genet. 2016-07-27 [PMID: 27466183] (WB, Mouse)
• Sato T, Ito Y, Nagasawa T. Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes Biosci. Biotechnol. Biochem. 2016-07-18 [PMID: 27427787]
• Wong AY, Hristova E, Ahlskog N et al. ABERRANT SUBCELLULAR DYNAMICS OF SIGMA-1 RECEPTOR MUTANTS UNDERLYING NEUROMUSCULAR DISEASES Mol. Pharmacol. 2016-07-14 [PMID: 27418673] (WB, Human)
• Ekser B, Mangus RS, Kubal CA et al. Recurrence of Hyperoxaluria and Kidney Disease after Combined Intestine-Kidney Transplantation for Enteric Hyperoxaluria Am. J. Nephrol. 2016-07-14 [PMID: 27410399] (WB, Mouse)
• Baradaran-Heravi Alireza, Balgi Aruna D, Zimmerman Carla et al. Novel small molecules potentiate premature termination codon readthrough by aminoglycosides. Nucleic Acids Research 2016-01-01 [PMID: 27407112] (WB, Human)
• Lee MC, Huang HJ, Chang TH et al. Genome-wide analysis of HIF-2alpha chromatin binding sites under normoxia in human bronchial epithelial cells (BEAS-2B) suggests its diverse functions. Sci Rep 2016-07-04 [PMID: 27373565] (WB)
• Xu Y, Li F, Zalzala M et al. Farnesoid X receptor activation increases reverse cholesterol transport by modulating bile acid composition and cholesterol absorption in mice Hepatology 2016-06-30 [PMID: 27359351] (WB)
• Goettsch C, Hutcheson JD, Hagita S et al. A single injection of gain-of-function mutant PCSK9 adeno-associated virus vector induces cardiovascular calcification in mice with no genetic modification. Atherosclerosis 2016-06-09 [PMID: 27318830] (WB, Mouse)
• Boddicker R L, Razidlo G L et al. Integrated mate-pair and RNA sequencing identifies novel, targetable gene fusions in peripheral T-cell lymphoma. Blood 2016-01-09 [PMID: 27297792] (WB, Human)
• Tsai WL, Yeh PH, Tsai CY et al. Efficient programming of human mesenchymal stem cell-derived hepatocytes by epigenetic regulations. J Gastroenterol Hepatol 2016-05-24 [PMID: 27218433] (WB, Human)
• Bhoopathi P, Lee N, Pradhan AK et al. mda-7/IL-24 induces cell death in neuroblastoma through a novel mechanism involving AIF and ATM. Cancer Research. 2016-04-13 [PMID: 27197168] (WB, Human)
  
  Details:
  Beta actin antibody was used for Western blot application in experiments involving human neuroblastoma cancer cell lines namely SK-N-AS, SK-NSH and NB1691.
• Pastore N, Brady OA, Diab HI et al. TFEB and TFE3 Cooperate in the Regulation of the Innate Immune Response in Activated Macrophages. Autophagy. 2016-05-12 [PMID: 27171064] (WB, Mouse)
• Radulovic M, Yoon H, Wu J et al. Targeting the thrombin receptor modulates inflammation and astrogliosis to improve recovery after spinal cord injury. Neurobiol. Dis. 2016-05-01 [PMID: 27145117] (WB, Mouse)
• Boothe T, Lim GE, Cen H et al. Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells. Mol Metab 2016-05-01 [PMID: 27110488] (WB)
• Lai CW, Chen HL, Tsai TC et al. Sexually Dimorphic Expression of eGFP Transgene in the Akr1A1 Locus of Mouse Liver Regulated by Sex Hormone-Related Epigenetic Remodeling. Sci Rep. 2016-04-18 [PMID: 27087367] (WB, Mouse)
• Xu J, Xu Y, Li Y et al. Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4alpha and Protects Against Alcohol- and MCD diet-induced Liver Injury. Sci Rep. 2016-04-14 [PMID: 27075303] (WB, Mouse)
• Acharya M, Sokolovska A, Tam JM et al. alphav Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016-03-11 [PMID: 26965188] (WB, Mouse)
• Naik E, Dixit VM. Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCbeta Kinase Activity. J. Immunol. 2016-03-02 [PMID: 26936881] (WB, Mouse)
  
  Details:
  GPR78 antibody was used for WB analysis of lysates from skin fibroblasts of Homocystinuria Patients with Remethylation Defects and control subjects. WB was also performed on lysates from cells treated or not with tunicamycin (Fig 1).
• Hong MN, Nam KY, Kim KK et al. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones 2016-05-01 [PMID: 26873011]
• Andreev E, Brosseau N, Carmona E et al. The human organic cation transporter OCT1 mediates high affinity uptake of the anticancer drug daunorubicin Sci Rep 2016-02-10 [PMID: 26861753] (WB, Human)
• Gosejacob D, Jager PS, Vom Dorp K et al. Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity. J. Biol. Chem. 2016-03-25 [PMID: 26853464] (WB, ELISA, Mouse)
• Rahtu-Korpela L, Maatta J et al. Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis. Arterioscler Thromb Vasc Biol 2016-01-04 [PMID: 26848160] (WB, Mouse)
• Yoon H, Kleven A, Paulsen A et al. Interplay between exercise and dietary fat modulates myelinogenesis in the central nervous system Biochim. Biophys. Acta 2016-01-26 [PMID: 26826016] (WB, Mouse)
• Maj M, Hoermann G, Rasul S et al. The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells. J Diabetes Res 2016-01-01 [PMID: 26824039] (WB)
• Westwell-Roper C, Denroche HC, Ehses JA, Verchere CB et al. Differential activation of innate immune pathways by distinct islet amyloid polypeptide (IAPP) aggregates J. Biol. Chem. 2016-01-19 [PMID: 26786104] (WB, Mouse)
• Bohnsack JP, Carlson SL, Morrow AL. Differential regulation of synaptic and extrasynaptic alpha4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons. Neuropharmacology 2016-06-01 [PMID: 26767953]
• Davis SM, Collier LA, Leonardo CC et al. Leukemia Inhibitory Factor Protects Neurons from Ischemic Damage via Upregulation of Superoxide Dismutase 3. Mol. Neurobiol. 2016-01-09 [PMID: 26746670] (WB, Rat)
• Lee SB, Frattini V, Bansal M et al. An ID2-dependent mechanism for VHL inactivation in cancer. Nature. 2016-01-14 [PMID: 26735018] (WB, Human)
• Cerqueira FM, Chausse B, Baranovski BM et al. Diluted Sera From Calorie Restricted Animals Promote Mitochondrial Beta-Cell Adaptations and Protect Against Glucolipotoxicity. FEBS J. 2016-01-06 [PMID: 26732506] (WB, Rat)
  
  Details:
  Beta-Actin antibody used for WB as a loading control on serum from AL and CR rats at a dilution of 1:2000 (Figure 3A).
• Lee KC, Hsieh YC, Yang YY et al. Aliskiren Reduces Hepatic steatosis and Epididymal Fat Mass and Increases Skeletal Muscle Insulin Sensitivity in High-Fat Diet-Fed Mice. Sci Rep 2016-01-06 [PMID: 26732252] (WB)
• Kral R, Doriguzzi A, Mayer CE et al. Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells. J. Cell. Biochem. 2016-01-05 [PMID: 26727965] (WB, Human)
  
  Details:
  Beta-Actin antibody used as a loading control for WB on WI-38, A549 and VL-8 cells that were infected with adenoviruses (Figure 1A).
• Yu CY, Liang JJ, Li JK et al. Dengue Virus Impairs Mitochondrial Fusion by Cleaving Mitofusins. PLoS Pathog. 2015-12-01 [PMID: 26717518] (WB, Human)
• Wang TK, Lin YM, Lo CM et al. Oncogenic roles of carbonic anhydrase 8 in human osteosarcoma cells. Tumour Biol. 2015-12-28 [PMID: 26711783] (WB, Human)
  
  Details:
  beta-Actin antibody (clone AC-15) was used for WB assays in experiments involving human osteosarcoma cell lines MG-63, U-2 OS, HOS and 143B and human embryonic kidney cell line HEK293.
• Laukka T, Mariani CJ, Ihantola T et al. Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes. J Biol Chem 2016-02-19 [PMID: 26703470]
• Vannuvel K, Van Steenbrugge M, Demazy C et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J. Cell. Physiol. 2015-12-17 [PMID: 26680008] (WB, Human)
• Sorrentino NC, Maffia V, Strollo S et al. A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs. Mol. Ther. 2015-12-07 [PMID: 26639405] (WB, Porcine)
• Suriben R, Kaihara KA, Paolino M et al. beta-Cell Insulin Secretion Requires the Ubiquitin Ligase COP1. Cell. 2015-12-03 [PMID: 26627735] (WB, Mouse)
• Yang Y, Jin Y, Du W. Programmed cell death 2 functions as a tumor suppressor in osteosarcoma. Int J Clin Exp Pathol. 2015-11-30 [PMID: 26617804] (WB, Rat)
• Fossati Silvia, Giannoni Patrizia, Solesio Maria E et al. The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain Neurobiol Dis 2016-02-01 [PMID: 26581638] (WB, Mouse)
  
  Details:
  Citation using the Purified form of this antibody.
• Cheng YF, Young GH, Lin JT et al. Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells. PLoS ONE. 2015-11-07 [PMID: 26544976] (WB, Human)
• Lin CL, Cheng YS, Li HH et al. Amyloid-beta suppresses AMP-activated protein kinase (AMPK) signaling and contributes to alpha-synuclein-induced cytotoxicity. Exp Neurol 2016-01-01 [PMID: 26515689]
• Lin CW, Chen YS, Lin CC et al. Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy. Sci Rep. 2015-10-30 [PMID: 26515640] (WB, Mouse)
• Weng WH, Leung WH, Pang YJ, Hsu HH Lauric acid can improve the sensitization of Cetuximab in KRAS/BRAF mutated colorectal cancer cells by retrievable microRNA-378 expression. Oncol Rep 2016-01-01 [PMID: 26496897]
• Karsikas S, Myllymaki M, Heikkila M et al. HIF-P4H-2 deficiency protects against skeletal muscle ischemia-reperfusion injury. J Mol Med (Berl) 2016-03-01 [PMID: 26452676]
• Shi C, Huang X, Zhang B et al. The Inhibition of Heat Shock Protein 90 Facilitates the Degradation of Poly-Alanine Expanded Poly (A) Binding Protein Nuclear 1 via the Carboxyl Terminus of Heat Shock Protein 70-Interacting Protein. PLoS One 2015-01-01 [PMID: 26414348] (Chemotaxis)
• Qiu Q, Yang C, Xiong W et al. SYK is a target of lymphocyte-derived microparticles in the induction of apoptosis of human retinoblastoma cells. Apoptosis 2015-12-01 [PMID: 26404525] (Human)
• Cox JV, Abdelrahman YM, Peters J et al. Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth Cell Microbiol. 2016-03-18 [PMID: 26381674] (WB, Human)
  
  Details:
  Citation using the Purified form of this antibody.
• Koukourakis MI, Kalamida D, Giatromanolaki A et al. Autophagosome Proteins LC3A, LC3B and LC3C Have Distinct Subcellular Distribution Kinetics and Expression in Cancer Cell Lines. PLoS One 2015-01-01 [PMID: 26378792] (WB, Human)
• Sato T, Ito Y, Nagasawa T. Dietary l-Lysine Suppresses Autophagic Proteolysis and Stimulates Akt/mTOR Signaling in the Skeletal Muscle of Rats Fed a Low-Protein Diet. J. Agric. Food Chem. 2015-09-23 [PMID: 26366928] (WB, Rat)
• Wu L, Zhang Z, Pan X et al. Expression and contribution of the HIF-1 alpha/VEGF signaling pathway to luteal development and function in pregnant rats Mol Med Rep 2015-09-02 [PMID: 26323652] (Rat)
• Radulovic M, Yoon H, Wu J et al. Genetic Targeting of Protease Activated Receptor 2 Reduces Inflammatory Astrogliosis and Improves Recovery of Function after Spinal Cord Injury. Neurobiol. Dis. 2015-08-24 [PMID: 26316358] (WB, Mouse)
• Sato T, Ito Y, Nagasawa T. Attenuation of autophagic-proteolysis in C2C12 cells by saccharopine. Mol. Cell. Biochem. 2015-08-26 [PMID: 26307368] (WB, Mouse)
• Lin CL, Huang WN, Li HH et al. Hydrogen-rich water attenuates amyloid beta-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells. Chem. Biol. Interact. 2015-08-10 [PMID: 26271894] (WB, Human)
  
  Details:
  beta-Actin antibody was used for WB analysis of lysates from human neuroblastoma SK-N-MC cells that were subjected to treatments with Amyloid beta and / or hydrogen-rich water in vitro.
• Juhasz T, Szentleleky E, Somogyi CS et al. Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Pathway Is Induced by Mechanical Load and Reduces the Activity of Hedgehog Signaling in Chondrogenic Micromass Cell Cultures. Int J Mol Sci. 2015-08-03 [PMID: 26230691] (WB, Chicken)
  
  Details:
  Collagen II antibody (clone 5B2.5) was used at 1:100 dilution for WB analysis of lysates from experiments involving chondrifying primary micromass cell cultures that were established from chicken embryos (Ross hybrid) of Hamburger-Hamilton stages 22–24. The cultures were treated or not with Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) PACAP 1–38 and/or transient MS.
• Lim GE, Albrecht T, Piske M et al. 14-3-3zeta coordinates adipogenesis of visceral fat. Nat Commun 2015-01-01 [PMID: 26220403] (IP)
• Bamidele AO, Kremer KN, Hirsova P et al. IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes J. Cell Biol. 2015-07-20 [PMID: 26195666] (WB, Human)
• Lin CW Jan MS Kuo JH. Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine. Mol Pharm. [PMID: 26158199]
• Yang C, Fischer-Keso R, Schlechter T et al. Plakophilin 1-deficient cells upregulate SPOCK1: implications for prostate cancer progression Tumour Biol. 2015-07-04 [PMID: 26138584] (WB, Human)
• Sasaki Y, Ohta M, Desai D et al. Angiopoietin Like Protein 2 (ANGPTL2) Promotes Adipose Tissue Macrophage and T lymphocyte Accumulation and Leads to Insulin Resistance PLoS ONE. 2015-07-03 [PMID: 26132105] (WB, Human, Mouse)
• Yang JS, Lin CW, Chuang CY et al. Carbonic anhydrase IX overexpression regulates the migration and progression in oral squamous cell carcinoma Tumour Biol. 2015-07-01 [PMID: 26130414] (WB, Human)
• Smith BW, Simpson DG, Miller RJ et al. Contrast Ultrasound Imaging Does Not Affect Heat Shock Protein 70 Expression in Cholesterol-Fed Rabbit Aorta J Ultrasound Med. 2015-07-01 [PMID: 26112623] (WB, Rabbit)
• Miki Y, Akimoto J, Moritake K et al. Photodynamic therapy using talaporfin sodium induces concentration-dependent programmed necroptosis in human glioblastoma T98G cells Lasers Med Sci. 2015-06-25 [PMID: 26109138] (WB, Human)
• Chang CJ, Lin CS, Lu CC et al. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota. Nat Commun 2015-01-01 [PMID: 26102296] (Mouse)
• Xu Y, Zalzala M, Xu J et al. A metabolic stress-inducible miR-34a-HNF4a pathway regulates lipid and lipoprotein metabolism Nat Commun 2015-06-23 [PMID: 26100857] (WB, Mouse)
• Billeter AT, Galbraith N, Walker S et al. TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response Surgery. 2015-06-05 [PMID: 26054320] (WB, Human)
• Viale-Bouroncle S, Klingelhoffer C, Ettl T, Morsczeck C. The AKT signaling pathway sustains the osteogenic differentiation in human dental follicle cells. Mol. Cell. Biochem. 2015-05-16 [PMID: 25981531] (WB, Human)
• Pang X, Wang Z, Yin D, Zhang Z. Overexpression of hypoxia-inducible factor prolyl- hydoxylase attenuated by HCG-induced vascular endothelial growth factor expression in luteal cells. Mol Med Rep 2015-05-16 [PMID: 25975603]
• Li HH, Lu FJ, Hung HC et al. Humic Acid Increases Amyloid beta-Induced Cytotoxicity by Induction of ER Stress in Human SK-N-MC Neuronal Cells.. Int J Mol Sci. 2015-05-07 [PMID: 25961951]
• Doriguzzi A, Haigl B, Gsur A, Sutterluty-Fall H. The increased Sprouty4 expression in response to serum is transcriptionally controlled by Specific protein 1. Int. J. Biochem. Cell Biol. 2015-05-06 [PMID: 25957915] (WB, Human)
• Wang ML, Lin SH, Hou YY, Chen YH. alpha-Naphthoflavone Increases Lipid Accumulation in Mature Adipocytes and Enhances Adipocyte-Stimulated Endothelial Tube Formation. Nutrients. 2015-05-06 [PMID: 25942489] (WB, Human)
• Yen JH, Lin LC, Chen MC, Sarang Z. The metastatic tumor antigen 1-transglutaminase-2 pathway is involved in selflimitationof monosodiumurate crystal-induced inflammation byupregulating TGF-beta1 Arthritis Research & Therapy 2015-02-26 [PMID: 25889736] (WB, Mouse, Human)
• Kao YT, Chang BL, Liang JJ et al. Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid beta-Oxidation PLoS Pathog. 2015-03-01 [PMID: 25816318] (WB, Human)
• Shaw D, Wang X, Brown L et al. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Nature Communications. [PMID: 25790189]
• Matteucci C, Minutolo A, Marino-Merlo F et al. Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB Life Sci. 2015-03-02 [PMID: 25744407] (WB, Human)
  
  Details:
  Beta-actin antibody was used as loading control for WB application in exeperiments involving AZT-induced NF-kB activation and its suppression by combined treatment with Bay-11-7085 in U937 cells (Fig. 2A).
• Wen J, Hanna CW, Martell S et al. Functional consequences of copy number variants in miscarriage Mol Cytogenet. 2015-02-12 [PMID: 25674159] (WB, Human)
• Capo-Chichi JM, Boissel S, Brustein E et al. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria J. Med. Genet. 2015-02-03 [PMID: 25650066] (WB, Human, Zebrafish)
• Yoon H, Radulovic M, Drucker KL et al. The thrombin receptor is a critical extracellular switch controlling myelination Glia. 2015-01-27 [PMID: 25628003] (WB, Mouse)
• Chong KY, Hsu CJ, Hung TH et al. Wnt pathway activation and ABCB1 expression account for attenuation of Proteasome Inhibitor-mediated apoptosis in multidrug-resistant cancer cells Cancer Biol. Ther. 2015-01-15 [PMID: 25590413] (WB)
• Peng CC, Lin YT, Chen KC et al. Antrodan, A beta-glucan obtained from Antrodia cinnamomea mycelia, is beneficial to benign prostate hyperplasia.. Food Funct. 2015-02-11 [PMID: 25537160]
• Taher Chato, Frisk Gabriella, Fuentes Stina et al. High prevalence of human cytomegalovirus in brain metastases of patients with primary breast and colorectal cancers. Transl Oncol. 2014-12-01 [PMID: 25500083]
• Lin Sp, Chiu Fy, Wang Y et al. RB Maintains Quiescence and Prevents Premature Senescence through Upregulation of DnMT1 in Mesenchymal Stromal Cells. Stem Cell Reports. 2014-11-06 [PMID: 25455074] (WB, Human)
• Hsin Ch, Chen Mk, Tang Ch et al. High level of plasma matrix metalloproteinase-11 is associated with clinicopathological characteristics in patients with oral squamous cell carcinoma. PLoS OnE. 2014-11-26 [PMID: 25423087] (WB, Human)
• Pan Wr, Chen Yl, Hsu Hc,Chen Wj. Antimicrobial peptide GW-H1-induced apoptosis of human gastric cancer AGS cell line is enhanced by suppression of autophagy. Mol. Cell. Biochem. 2014-11-08 [PMID: 25380626] (WB, Human)
• Liu Y, Shim E, Crespo-Mejias Y et al. Cardiomyocytes are Protected from Antiretroviral nucleoside Analog-Induced Mitochondrial Toxicity by Overexpression of PGC-1Alpha Cardiovasc. Toxicol. 2014-11-07 [PMID: 25377427] (WB, Rat)
  
  Details:
  Beta actin antibody used for WB in experiments involving H9c2 cell line (derived from embryonic rat heart tissue).
• Chan Mt, Lim Ge, Skovso S et al. Effects of insulin on human pancreatic cancer progression modeled in vitro BMC Cancer et al. 2014-11-14 [PMID: 25373319] (WB, Human)
  
  Details:
  Beta actin antibody used as loading control for WB in experiments involving human primary pancreatic ductal cells, human HPDE cells and human PAnC1 cells.
• Lajud Sa, Nagda Da, Yamashita T et al. Dual Disruption of DnA Repair and Telomere Maintenance for the Treatment of Head and neck Cancer. Clin. Cancer Res. 2014-10-16 [PMID: 25324139] (WB, Human)
• Kokontis JM, Lin HP, Jiang SS et al. Androgen Suppresses the Proliferation of Androgen Receptor-Positive Castration-Resistant Prostate Cancer Cells via Inhibition of Cdk2, CyclinA, and Skp2. PLoS ONE. 2014-10-02 [PMID: 25271736] (WB, Human)
• Fischer-Keso R, Breuninger S, Hofmann S et al. Plakophilins 1 and 3 Bind to FXR1 and Thereby Influence the mRNA Stability of Desmosomal Proteins. Mol Cell Biol 2014-12-01 [PMID: 25225333]
• Naik E, Webster JD, DeVoss J et al. Regulation of proximal T cell receptor signaling and tolerance induction by deubiquitinase Usp9X. J Exp. Med. 2014-09-22 [PMID: 25200027] (WB, Mouse)
• Qin Q, Xie H, Wise SS et al. Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavalent Chromium Exposure Suppresses the Rad51 Response in Human Lung Cells. Toxicol. Sci. 2014-08-30 [PMID: 25173789] (WB, Human)
• Yang NC, Song TY, Chang YZ et al. Up-regulation of nicotinamide phosphoribosyltransferase and increase of NAD+ levels by glucose restriction extend replicative lifespan of human fibroblast Hs68 cells.. Biogerontology. 2015-02-01 [PMID: 25146190]
• Hung YW, Hung SW, Wu YC et al. Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy Brain Behav. Immun. 2014-08-15 [PMID: 25135858]
• Dill-McFarland KA, Neil KL, Zeng A et al. Hibernation alters the diversity and composition of mucosa-associated bacteria while enhancing antimicrobial defense in the gut of 13-lined ground squirrels. Mol. Ecol. 2014-08-12 [PMID: 25130694] (WB, Mammal)
• Di K, Keir ST, Alexandru-Abrams D et al. Profiling Hsp90 differential expression and the molecular effects of the Hsp90 inhibitor IPI-504 in high-grade glioma models J. Neurooncol. 2014-08-13 [PMID: 25115740]
• Benayoun BA, Pollina EA, Ucar D et al. H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency Cell 2014-07-31 [PMID: 25083876]
• Lin CW, Jan MS, Kuo JH. Autophagy-related gene expression analysis of wild-type and atg5 gene knockout mouse embryonic fibroblast cells treated with polyethylenimine. Mol Pharm. 2014-09-02 [PMID: 25075440]
• Bohr M, Brooks AR, Kurtz CC. Hibernation induces immune changes in the lung of 13-lined ground squirrels (Ictidomys tridecemlineatus). Dev. Comp. Immunol. 2014-07-18 [PMID: 25046152] (WB, Squirrel)
  
  Details:
  Beta Actin antibody used as loading control for WB on lung of 13-lined ground squirrels (Ictidomys tridecemlineatus).
• Vande Walle Lieselotte, Van Opdenbosch Nina, Jacques Peggy et al. Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis. Nature 2014-08-07 [PMID: 25043000] (WB, Mouse)
  
  Details:
  Using the HRP conjugated version of NB600-501, catalog number NB600-501H.
• Chen Chin-Chen, Lin Jiun-Tsai, Cheng Yi-Fang et al. Amelioration of LPS-induced inflammation response in microglia by AMPK activation. Biomed Res Int. 2014-06-17 [PMID: 25025067]
• Wu CM, Lin KW, Teng CH et al. Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells. Biol. Pharm. Bull. 2014-07-03 [PMID: 24989010] (WB, Human)
  
  Details:
  Beta actin antibody used as a loading control in WB application in lysates of human bladder cancer cells NTUB1.
• Lin KW, Huang AM, Lin CC et al. Anti-cancer effects of ursane triterpenoid as a single agent and in combination with cisplatin in bladder cancer Eur. J. Pharmacol. 2014-06-14 [PMID: 24933647] (WB, Human)
  
  Details:
  Beta Actin antibody used as loading control in WB assays on NTUB1 (a human bladder carcinoma cell) treated or not with Ursolic acid derivative isopropyl 3beta-hydroxyurs-12-en-28-oat (UA17) and cisplatin combinations. WB Images - Fig. 3C, Fig. 10 B and C.
• Chung PJ, Chi LM, Chen CL et al. microRNA-205 targets tight junction-related proteins during urothelial cellular differentiation. Mol. Cell Proteomics. 2014-06-09 [PMID: 24912853] (WB, Mouse)
  
  Details:
  Beta Actin antibody used for WB in 550ug lysate of normal urothelial cells (isolated from mouse bladder) treated with the antogomir against miR-205 (antagomiR-205 or Ant-205) or scramble control.
• Rahtu-Korpela Lea, Karsikas Sara, Horkko Sohvi et al. HIF prolyl 4-hydroxylase-2 inhibition improves glucose and lipid metabolism and protects against obesity and metabolic dysfunction. Diabetes. 2014-05-01 [PMID: 24789921] (Mouse)
• Press T, Viale-Bouroncle S, Felthaus O et al. EGR1 supports the osteogenic differentiation of dental stem cells. Int Endod J 2014-04-21 [PMID: 24749562] (WB, Human)
• Zeng W, Guo YH, Qi W et al. 4-Phenylbutyric acid suppresses inflammation through regulation of endoplasmic reticulum stress of endothelial cells stimulated by uremic serum. Life Sci. 2014-03-17 [PMID: 24650493] (WB, Human)
• Brugger D, Buffler M, Windisch W. Development of an experimental model to assess the bioavailability of zinc in practical piglet diets. Arch Anim Nutr 2014-04-01 [PMID: 24646148] (WB, Porcine)
  
  Details:
  Using the HRP conjugated version of NB600-501, catalog number NB600-501H.
• Xia S Function and mechanism of the gasdermin family Thesis 2021-01-01 (WB, Mouse)
• Wong TW, Doyle AD, Lee JJ, Jelinek DF. Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans. J. Immunol. 2014-03-10 [PMID: 24616476] (WB, Human)
• Cai B, Xie S, Liu F et al. Rapid Degradation of the Complement Regulator, CD59, by a Novel Inhibitor. J. Biol. Chem. 2014-03-10 [PMID: 24616098] (WB, Human)
• Liu Y, Shim E, Nguyen P et al. Tempol Protects Cardiomyocytes from Nucleoside Reverse Transcriptase Inhibitor-Induced Mitochondrial Toxicity. Toxicol. Sci. 2014-03-10 [PMID: 24591154] (WB, Rat)
• Hung TM, Ho CM, Liu YC et al. Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular Carcinoma. PLoS ONE 2014-03-03 [PMID: 24586785] (WB, Human)
• Van Opdenbosch Nina, Gurung Prajwal, Vande Walle Lieselotte et al. Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation. Nat Commun 2014-01-01 [PMID: 24492532] (WB)
  
  Details:
  Using the HRP conjugated version of NB600-501, catalog number NB600-501H.
• Liang JJ, Wei JC, Lee YL et al. Surfactant-modified nanoclay exhibits an antiviral activity with high potency and broad spectrum. J. Virol. 2014-01-30 [PMID: 24478435] (WB, Hamster, Human)
• Yu CH, Yu CC. Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. PLoS ONE 2014-01-29 [PMID: 24475244] (WB, Human)
• D'souza AM, Asadi A, Johnson JD, Kieffer TJ. Leptin Deficiency in Rats Results in Hyperinsulinemia and Impaired Glucose Homeostasis. Endocrinology 2014-01-28 [PMID: 24467741] (WB, Rat)
• Kaczmarek MZ, Holland RJ, Lavanier SA et al. Mechanism of action for the cytotoxic effects of the nitric oxide prodrug JS-K in murine erythroleukemia cells. Leuk Res 2013-12-12 [PMID: 24461365] (WB, Mouse)
• Li KW, Yu YP, Zhou C et al. Calcium channel alpha-2-delta1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis. J. Biol. Chem. 2014-01-24 [PMID: 24459143] (WB, Rat)
• Zhu M, Guo M, Fei L et al. 4-Phenylbutyric acid attenuates endoplasmic reticulum stress-mediated pancreatic beta-cell apoptosis in rats with streptozotocin-induced diabetes. Endocrine 2013-12-18 [PMID: 24347242] (WB, Rat)
• Mounce BC, Mboko WP, Kanack AJ et al. Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. J. Virol. 2014-02-01 [PMID: 24335310] (WB, Mouse)
• Viale-Bouroncle S, Gosau M, Morsczeck C. NOTCH1 signaling regulates the BMP2/DLX-3 directed osteogenic differentiation of dental follicle cells. Biochem Biophys Res Commun. 2013-12-07 [PMID: 24321094] (WB, Human)
• Schusser B, Yi H, Collarini EJ et al. Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire. PLoS One. 2013-11-21 [PMID: 24278246] (WB, Chicken)
• Govaert KM, Emmink BL, Nijkamp MW et al. Hypoxia After Liver Surgery Imposes an Aggressive Cancer Stem Cell Phenotype on Residual Tumor Cells. Ann Surg 2013-11-18 [PMID: 24253142] (WB, Mouse)
• Allache R, Lachance S, Guyot MC et al. Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway. Hum Mol Genet. 2013-11-18 [PMID: 24203697] (WB, Human)
• Zhou C, Luo ZD. Electrophysiological characterization of spinal neuron sensitization by elevated calcium channel alpha-2-delta-1 subunit protein. Eur J Pain. 2013-10-23 [PMID: 24151064]
• Thies HW, Nolte I, Wenk H et al. Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue. Obesity (Silver Spring). 2012-11-06 [PMID: 24106133] (WB, Human, Canine)
• Li KW, Kim DS, Zaucke F et al. Trigeminal nerve injury-induced thrombospondin-4 up-regulation contributes to orofacial neuropathic pain states in a rat model. Eur J Pain. 2013-09-09 [PMID: 24019258]
• Liu L, Martin R, Kohler G, Chan C. Palmitate induces transcriptional regulation of BACE1 and presenilin by STAT3 in neurons mediated by astrocytes. Exp Neurol 2013-10-01 [PMID: 23968646] (WB, Rat)
  
  Details:
  Using the HRP conjugated version of NB600-501, catalog number NB600-501H.
• Galasso C. Marine Biotechnology: a sea of new resources and solutions for ocean and human health. Thesis. 1905-07-09 (Human)
• Chang KP, Wang CL, Kao HK et al. Overexpression of caldesmon is associated with lymph node metastasis and poorer prognosis in patients with oral cavity squamous cell carcinoma. Cancer. 2013-08-20 [PMID: 23963810] (WB, Human)
• Hsieh YT, Chou MM, Chen HC, Tseng JJ. IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1. Gynecol Oncol. 2013-10-01 [PMID: 23911878]
• Carmony KC. Elucidating Proteasome Catalytic Subunit Composition and Its Role in Proteasome Inhibitor Resistance. Thesis. 2016-04-18 (WB, Human)
• Zheng Xiaoxu, Heaps Cristine L, Fisher Steven A. Myosin phosphatase isoforms and related transcripts in the pig coronary circulation and effects of exercise and chronic occlusion. Microvasc Res. 2014-01-01 [PMID: 24534069] (Bovine)
• Lin HP, Lin CY, Hsiao PH et al. Difference in Protein Expression Profile and Chemotherapy Drugs Response of Different Progression Stages of LNCaP Sublines and Other Human Prostate Cancer Cells. PLoS One 2013-12-05 [PMID: 24349321] (WB, Human)
• Xu J, Li Y, Chen WD et al. Hepatic carboxylesterase 1 Is essential for both normal and farnesoid X receptor-controlled lipid homeostasis. Hepatology. 2013-08-28 [PMID: 24038130] (WB, Mouse)
• Su S, Chen Y, Chien C et al. PDIA4: A Novel ER Stress Protein Regulating Hepatic Lipogenesis in Non-Alcoholic Fatty Liver Disease Research Square 2023-06-13 (WB, Human)
• Gini B, Zanca C, Guo D et al. The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res 2013-10-15 [PMID: 24030701]
• Snoeren N, Emmink BL, Koerkamp MJ et al. Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer. Br J Cancer. 2013-09-17 [PMID: 24002600] (WB, Human)
• Feldman AL, Vasmatzis G, Asmann YW et al. Novel TRAF1-ALK fusion identified by deep RNA sequencing of anaplastic large cell lymphoma. Genes Chromosomes Cancer. 2013-09-02 [PMID: 23999969] (WB, Human)
• Chan CC, Lee KC, Huang YH et al. Regulation by Resveratrol of the Cellular Factors Mediating Liver Damage and Regeneration after Acute Toxic Liver Injury. J Gastroenterol Hepatol. 2013-08-23 [PMID: 23981054] (WB, Mouse)
• Khan Z, Yaiw KC, Wilhelmi V et al. Human cytomegalovirus immediate early proteins promote degradation of connexin 43 and disrupt gap junction communication: implications for a role in gliomagenesis. Carcinogenesis 2014-01-01 [PMID: 23978378]
• Hsu PK, Chen HY, Yeh YC et al. TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma. J Gastroenterol. 2013-08-21 [PMID: 23963785] (WB, Human)
• Lee CC, Lai YT, Chang HT et al. Inhibition of high-mobility group box 1 in lung reduced airway inflammation and remodeling in a mouse model of chronic asthma. Biochem Pharmacol. 2013-08-12 [PMID: 23948063] (WB, Mouse)
• Yeh CN, Chiang KC, Juang HH et al. Reappraisal of the Therapeutic Role of Celecoxib in Cholangiocarcinoma. PLoS One 2013-07-26 [PMID: 23922859] (WB, Rat)
• Morel E, Chamoun Z, Lasiecka ZM et al. Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system. Nat Commun 2013-08-02 [PMID: 23907271] (WB, Human)
• Tigrine C, Bulzomi P, Leone S et al. Cleome arabica leaf extract has anticancer properties in Human cancer cells. Pharm Biol 2013-07-18 [PMID: 23862683] (WB, Human)
• Wen J, Lopes F, Soares G et al. Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2. Orphanet J Rare Dis 2013-07-10 [PMID: 23837398] (WB, Human)
• Emmink BL, Verheem A, Van Houdt WJ et al. The secretome of colon cancer stem cells contains drug-metabolizing enzymes. J Proteomics 2013-07-05 [PMID: 23835434] (WB, Human)
• Rathmanner N, Haigl B, Vanas V et al. Sprouty2 but not Sprouty4 is a potent inhibitor of cell proliferation and migration of osteosarcoma cells. FEBS Lett 2013-07-04 [PMID: 23831057] (WB, Human)
• Kremer KN, Peterson KL, Schneider PA et al. SDF-1/CXCR4 signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak. J Biol Chem 2013-06-24 [PMID: 23798675] (WB, Human)
• Ko CH, Cheng CF, Lai CP et al. Differential proteomic analysis of cancer stem cell properties in hepatocellular carcinomas by isobaric tag labeling and mass spectrometry. J Proteome Res 2013-08-02 [PMID: 23782096] (WB, Human)
• Shie MY, Ding SJ. Integrin binding and MAPK signal pathways in primary cell responses to surface chemistry of calcium silicate cements. Biomaterials 2013-09-01 [PMID: 23768900] (ELISA, Human)
• Liu T, Zhang S, Xiang D, Wang Y. Induction of hepatocyte-like cells from mouse embryonic stem cells by lentivirus-mediated constitutive expression of Foxa2/Hnf4a. J Cell Biochem 2013-06-06 [PMID: 23744720] (WB, Mouse)
• Babic I, Anderson ES, Tanaka K et al. EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer. Cell Metab 2013-06-04 [PMID: 23707073] (WB, Human)
• Formosa R, Xuereb-Anastasi A, Vassallo J. AIP regulates cAMP signalling and growth hormone secretion in GH3 cells. Endocr Relat Cancer 2013-05-23 [PMID: 23702468] (ICC/IF, WB, Rat)
• Das I, Png CW, Oancea I et al. Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. J Exp Med 2013-05-06 [PMID: 23650437] (WB, Human)
• Zeng J, Kim D, Li KW et al. Thrombospondin-4 contributes to spinal cord injury-induced changes in nociception. Eur J Pain 2013-05-07 [PMID: 23649982]
• Yoon H, Radulovic M, Wu J et al. Kallikrein 6 signals through PAR1 and PAR2 to promote neuron injury and exacerbate glutamate neurotoxicity. J Neurochem. 2013-10-01 [PMID: 23647384] (WB, IP, Mouse)
• Rafalski VA, Ho PP, Brett JO et al. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain.. Nat Cell Biol 2013-06-01 [PMID: 23644469] (WB, Mouse)
• Cai H, Peng F. Knockdown of copper chaperone antioxidant-1 by RNA interference inhibits copper-stimulated proliferation of non-small cell lung carcinoma cells. Oncol Rep 2013-07-01 [PMID: 23624903]
• Kral RM, Mayer CE, Vanas V et al. In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected. Cell Biochem Funct 2013-04-24 [PMID: 23616430] (WB, Human)
• Huang TT, Chong KY, Ojcius DM et al. Hirsutella sinensis mycelium suppresses interleukin-1beta and interleukin-18 secretion by inhibiting both canonical and non-canonical inflammasomes. Sci Rep 2013-03-05 [PMID: 23459183] (WB, Human)
• Park Y, Carr TPet al. Unsaturated fatty acids and phytosterols regulate cholesterol transporter genes in Caco-2 and HepG2 cell lines. Nutr Res. 2013-02-01 [PMID: 23399666] (WB, Human)
• Allen JJ, Bell GR, Kuzirian AM, Hanlon RT. Cuttlefish skin papilla morphology suggests a muscular hydrostatic function for rapid changeability. J Morphol 2013-02-02 [PMID: 23378271] (IF/IHC, ICC/IF, Fish)
• Drucker KL, Paulsen AR, Giannini C et al. Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma Neuro Oncol 2013-01-10 [PMID: 23307575] (WB, Human)
• Salih DA, Rashid AJ, Colas D et al. FoxO6 regulates memory consolidation and synaptic function Genes Dev 2012-12-15 [PMID: 23222102] (WB, Mouse)
• Shih H J, Chen H H et al. Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity. Oncotarget 2012-01-11 [PMID: 23211466] (WB, Human)
• Berryer MH, Hamdan FF, Klitten LL et al. Mutations in SYNGAP1 Cause Intellectual Disability, Autism, and a Specific Form of Epilepsy by Inducing Haploinsufficiency Hum Mutat 2012-11-15 [PMID: 23161826] (WB, Human)
• Xie W, Parker JL, Heaps CL. Exercise Training-Enhanced, Endothelium-Dependent Dilation Mediated by Altered Regulation of BK(Ca) Channels in Collateral-Dependent Porcine Coronary Arterioles. Microcirculation 2013-02-01 [PMID: 23002811]
• Lin CW, Jan MS, Kuo JH et al. Protective role of autophagy in branched polyethylenimine (25K)- and poly(L-lysine) (30-70K)-induced cell death. Eur J Pharm Sci. 2012-12-18 [PMID: 23000135] (WB, Human)
• Hanell A, Clausen F, Djupsjo A et al. Functional and Histological Outcome after Focal Traumatic Brain Injury Is Not Improved in Conditional EphA4 Knockout Mice J Neurotrauma 2012-11-01 [PMID: 22985250]
• Lee WC, Kan D, Chen YY et al. Suppression of Extensive Neurofilament Phosphorylation Rescues alpha-Internexin/Peripherin-Overexpressing PC12 Cells from Neuronal Cell Death PLoS One 2012-01-01 [PMID: 22952800] (WB, Rat)
• Aro E, Khatri R, Gerard-O'Riley R et al. Hypoxia-inducible factor-1 (HIF-1) but not HIF-2 is essential for hypoxic induction of collagen prolyl 4-hydroxylases in primary newborn mouse epiphyseal growth plate chondrocytes J Biol Chem 2012-08-28 [PMID: 22930750] (WB, Mouse)
• Maj M, Milenkovic I, Bauer J et al. Novel insights into the distribution and functional aspects of the calcium binding protein secretagogin from studies on rat brain and primary neuronal cell culture Front Mol Neurosci 2012-01-01 [PMID: 22888312] (WB, Human, Rat)
• Minutolo A, Grelli S, Marino-Merlo F et al. D(-)lentiginosine-induced apoptosis involves the intrinsic pathway and is p53-independent Cell Death Dis 2012-07-26 [PMID: 22833097] (WB, Human)
• Calnan DR, Webb AE, White JL et al. Methylation by Set9 modulates FoxO3 stability and transcriptional activity Aging 2012-07-01 [PMID: 22820736] (WB, Human)
• Wu H, Lu Y, Shen C et al. Distinct Roles of Muscle and Motoneuron LRP4 in Neuromuscular Junction Formation Neuron 2012-07-12 [PMID: 22794264] (WB, Mouse)
• Wu MR, Hou MH, Lin YL, Kuo CF. 2,4,5-TMBA, a natural inhibitor of cyclooxygenase-2, suppresses adipogenesis and promotes lipolysis in 3T3-L1 adipocytes.. J Agric Food Chem. 2012-07-25 [PMID: 22746947]
• Li T, Liu G, Li J, Wang X, Liu Q, Liu Z, Du W. Mechanisms of Prostate Permeability Triggered by Microbubble-Mediated Acoustic Cavitation Cell Biochem Biophys 2012-06-22 [PMID: 22722876] (WB, Rabbit)
• Wehenkel M, Ban JO, Ho YK et al. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice Br J Cancer 2012-06-26 [PMID: 22677907] (WB, Human)
• Dawson PA, Rakoczy J, Simmons DG. Placental, Renal, and Ileal Sulfate Transporter Gene Expression in Mouse Gestation Biol Reprod 2012-08-23 [PMID: 22674389] (WB, Mouse)
• Wu H, Lu Y, Barik A et al. Beta-Catenin gain of function in muscles impairs neuromuscular junction formation Development 2012-07-01 [PMID: 22627288] (WB, Mouse)
• Herroon MK, Rajagurubandara E, Rudy DL, Chalasani A, Hardaway AL, Podgorski I. Macrophage cathepsin K promotes prostate tumor progression in bone. Oncogene. 2012-05-21 [PMID: 22614014] (WB, Human)
• Raimo Pohjanvirta, Hanna Miettinen, Satu Sankari, Nagabhooshan Hegde, Jere Linden. Unexpected gender difference in sensitivity to the acute toxicity of dioxin in mice, . Toxicology and Applied Pharmacology, 10.1016/j.taap.2012.04.032. 2012-01-01 [PMID: 22564538] (WB, Mouse)
• Yu M, Ge C, Zeng W et al. Retinoic acid promotes proliferation of chicken primordial germ cells via activation of PI3K/Akt-mediated NF-kappa B signalling cascade Cell Biol Int 2012-08-01 [PMID: 22548360] (WB, Chicken)
• Chang WW, Hu FW, Yu CC et al. Quercetin in elimination of tumor initiating stem-like and mesenchymal transformation property in head and neck cancer Head Neck 2013-03-01 [PMID: 22422628] (WB, Human)
• Hsieh YL, Chou LW, Chang PL, Yang CC, Kao MJ, Hong CZ. Low-level laser therapy alleviates neuropathic pain and promotes function recovery in rats with chronic constriction injury-possible involvements in hypoxia-inducible factor 1? (HIF-1?). J Comp Neurol doi: 10.1002/cne.23072. 2012-02-20 [PMID: 22351621]
• Carmony KC, Kim KB. PROTAC-induced proteolytic targeting. Methods Mol Biol 2012-01-01 [PMID: 22350917] (Human)
• Govaert KM, Nijkamp MW, Emmink BL, Steller EJ, Minchinton AI, Kranenburg O, Borel Rinkes IH. Effects of tirapazamine on experimental colorectal liver metastases after radiofrequency ablation. Br J Surgr;99(4):567-75. doi: 10.1002/bjs.8668. 2012-04-01 [PMID: 22331808]
• Zhang B, Liang C, Bates R et al. Wnt proteins regulate acetylcholine receptor clustering in muscle cells Mol Brain 2012-02-06 [PMID: 22309736] (WB, Mouse)
• Rahardjo AK Effects of eukaryotic initiation factor 2A upregulation on protein synthesis in insulin producing cells Thesis 2022-01-01 (WB, Human, Mouse)
• Stan T, Vijver D, Verhaart I, Aartsma-Rus A The vitamin B3analogue nicotinamide riboside has only very minor effects on reducing muscle damage inmdxmice bioRxiv 2023-02-03 (WB, Mouse)
• Zhou Q, Xu G, Zhang X, Cao C, Zhou Z. Proteomics of post-traumatic proliferative vitreoretinopathy in rabbit retina reveals alterations to a variety of functional proteins. Curr Eye Res37(4):318-26. 2012-04-01 [PMID: 22295879] (WB, Rabbit)
• Swain U, Rao KS. Age-dependent decline of DNA base excision repair activity in rat cortical neurons. Mech Ageing Dev. 2012-04-01 [PMID: 22266244] (WB, Rat)
• Edgel KA, McMillen TS, Wei H et al. Obesity and weight loss result in increased adipose tissue ABCG1 expression in db/db mice. Biochim Biophys Acta 2012-03-01 [PMID: 22179025] (WB, Mouse)
• Tsai YY, Huang YH, Chao YL, Hu KY, Chin LT, Chou SH, Hour AL, Yao YD, Tu CS, Liang YJ, Tsai CY, Wu HY, Tan SW, Chen HM. Identification of the nanogold particle-induced endoplasmic reticulum stress by omic techniques and systems biology analysis. ACS Nano;5(12):9354-69. 2011-12-27 [PMID: 22107733] (WB, Human)
• Khan Z, Akhtar M, Ekstrom TJ. HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase. Int J Mol Med 2011-12-01 [PMID: 21894430] (WB, Human)
• Gao L, Coope H, Grant S et al. ABIN1 protein cooperates with TAX1BP1 and A20 proteins to inhibit antiviral signaling. J Biol Chem 2011-10-21 [PMID: 21885437]
• Chia-Feng Kuo, Chih-Hsuan Hsieh, Wun-Yuan Lin. Proteomic response of LAP-activated RAW 264.7 macrophages to the anti-inflammatory property of fungal ergosterol.. Food chemistry. 2011-01-01
• Lee Wen-Ching, Chen Yun-Yu, Kan Daphne et al. A neuronal death model: overexpression of neuronal intermediate filament protein peripherin in PC12 cells. Journal of Biomedical Science 2012-01-01 [PMID: 22252275] (WB, Mouse)
• Szabat M, Kalynyak TB, Lim GE et al. Musashi expression in [beta]-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes. Cell Death Dis 20112:e232. [PMID: 22113197]
• Yang L-X, Yang Z-H, Guo R-W et al. Angiotensin II induces extracellular matrix metalloproteinase inducer expression via an AT1R dependent pathway in aortic atherosclerotic plaque in apolipoprotein E knockout mice. J Renin Angiotensin Aldosterone Syst. 2011-10-21 [PMID: 22020146]
• Chiang K-C, Yeh C-N, Chen H-Y et al. 19-Nor-2[alpha]-(3-hydroxypropyl)-1[alpha],25-dihydroxyvitamin D(3) (MART-10) is a potent cell growth regulator with enhanced chemotherapeutic potency in liver cancer cells. Steroids. 2011-08-25 [PMID: 21888924]
• van Houdt W J, Emmink B L et al. Comparative proteomics of colon cancer stem cells and differentiated tumor cells identifies BIRC6 as a potential therapeutic target. Mol Cell Proteomics 2011-01-12 [PMID: 21788403] (WB, Human)
• Patschan O, Shariat SF, Chade DC et al. Association of tumor-associated trypsin inhibitor (TATI) expression with molecular markers, pathologic features and clinical outcomes of urothelial carcinoma of the urinary bladder World J Urol 2012-12-01 [PMID: 21739120] (IF/IHC, Human)
• Corcoran MP, Lichtenstein AH, Meydani M et al. The effect of 17{beta}-estradiol on cholesterol content in human macrophages is influenced by the lipoprotein milieu. J Mol Endocrinol. 2011-06-06 [PMID: 21646386] (WB, Human)
• Ge X, Yin L, Ma H et al. Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis. [PMID: 21642744]
• Vitari AC, Leong KG, Newton K et al. COP1 is a tumour suppressor that causes degradation of ETS transcription factors. Nature 2011-06-16 [PMID: 21572435]
• Winter N, Nimzyk R, Bosche C et al. Chromatin immunoprecipitation to analyze DNA binding sites of HMGA2 PLoS One 2011-04-14 [PMID: 21533145] (WB, Human)
• Huang AM, Kao YT, Toh S et al. UBE2M-mediated p27(kip1) degradation in gemcitabine cytotoxicity. Biochem Pharmacol 2011-07-01 [PMID: 21477582] (WB, Human)
• Scarisbrick IA, Epstein B, Cloud BA et al. Functional Role of Kallikrein 6 in Regulating Immune Cell Survival. PLoS ONE. 2011-03-28 [PMID: 21464892]
• HildebrJM, Luo Z, Manske MK et al. A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling. J Exp Med. 2010-11-01 [PMID: 21041452]
• Smith B. Effects of nutrition and ultrasound imaging on the cardiovascular system Thesis. 2014-01-01 (WB, Rabbit)
• Nijkamp MW, Hoogwater FJ, Govaert KM et al. A role for CD95 signaling in ischemia/reperfusion-induced invasion and outgrowth of colorectal micrometastases in mouse liver J Surg Oncol 2011-08-01 [PMID: 21506133] (WB, Mouse)
• Raats DA, de Bruijn MT, Steller EJ et al. Synergistic killing of colorectal cancer cells by oxaliplatin and ABT-737. Cell Oncol (Dordr). 2011-08-01 [PMID: 21468686]
• Kim SJ, Nian C, McIntosh CH. Adipocyte expression of the glucose-dependent insulinotropic polypeptide receptor involves gene regulation by PPARgamma and histone acetylation. J Lipid Res 2011-04-01 [PMID: 21245029] (WB, Mouse)
• Mahmoudi S, Mancini E, Moore A et al. Old fibroblasts secrete inflammatory cytokines that drive variability in reprogramming efficiency and may affect wound healing between old individuals bioRxiv 2018-10-20 (WB, Mouse, Human)
• Chen CC, Chyau CC, Liao CC et al. Enhanced anti-inflammatory activities of Monascus pilosus fermented products by addition of ginger to the medium.. J Agric Food Chem. 2010-11-24 [PMID: 20958048]
• Herroon MK, Diedrich JD, Rajagurubandara E Prostate Tumor Cell-Derived IL1b Induces an Inflammatory Phenotype in Bone Marrow Adipocytes and Reduces Sensitivity to Docetaxel via Lipolysis-Dependent Mechanisms researchgate.net (Mouse)
• Chowdhury, A Tamalin/GRAS-1 Connects Glutamate Receptor Activity to the Insulin/IGF Signaling Cascade to Regulate Neuroprotection in a Nematode Model of Excitotoxicity Thesis 2020-01-01 (WB, C. elegans)
• Moiseyev, G et al Inhibition of the visual cycle by A2E through direct interaction with RPE65 and implications in Stargardt disease. Proc Natl Acad Sci U S A 2010-10-12 [PMID: 20876139]
  
  Details:
  Using the Purified form of this antibody.
• Chavez CL, Keravala A, Woodard LE et al. Kinetics and longevity of PhiC31 integrase in mouse liver and cultured cells. Hum Gene Ther 2010-10-01 [PMID: 20497035] (WB)
• van Houdt WJ, de Bruijn MT, Emmink BL et al. Oncogenic K-ras activates p38 to maintain colorectal cancer cell proliferation during MEK inhibition. Cell Oncol 2010-01-01 [PMID: 20413844]
• de Bruijn MT, Raats DA, Hoogwater FJ et al. Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa Br J Cancer 2010-04-01 [PMID: 20354524] (WB, Human)
  
  Details:
  Citation using the Non-Recombinant Monoclonal format of this antibody.
• Lan CH, Sheng JQ, Fang DC et al. Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells. J Dig Dis 2010-02-01 [PMID: 20132430] (WB, Human)
• Matluk N, Rochira JA, Karaczyn A et al. A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. BMC Biol 2010-01-01 [PMID: 20100315] (WB)
• M Maj, W Gartner, A Ilhan et al. Expression of TAU in insulin-secreting cells and its interaction with the calcium-binding protein secretagogin. J. Endocrinol. 205 (1): 25-36. 2010-01-01 [PMID: 20061514]
• Macchi B, Minutolo A, Grelli S et al. The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. Glycobiology 2010-05-01 [PMID: 20053629] (WB, Human)
• Woodard LE, Hillman RT, Keravala A et al. Effect of nuclear localization and hydrodynamic delivery-induced cell division on phiC31 integrase activity. Gene Ther 2010-02-01 [PMID: 19847205] (WB, Human)
• Zhang B, Luo S, Wang Q et al. LRP4 serves as a coreceptor of agrin. Neuron 2008-10-23 [PMID: 18957220] (WB)
• Luo S, Zhang B, Dong XP et al. HSP90 beta regulates rapsyn turnover and subsequent AChR cluster formation and maintenance. Neuron 2008-10-09 [PMID: 18940591] (Mouse)
• Fogarty JA, Delp MD, Muller-Delp JM et al. Neuropilin-1 is essential for enhanced VEGF(165)-mediated vasodilatation in collateral-dependent coronary arterioles of exercise-trained pigs. J Vasc Res 2009-01-01 [PMID: 18769069] (WB)
• Barthel SR, Gavino JD, Wiese GK et al. Analysis of glycosyltransferase expression in metastatic prostate cancer cells capable of rolling activity on microvascular endothelial (E)-selectin. Glycobiology;18(10):806-17. 2008-10-01 [PMID: 18647941]
• Elsawa Sherine F, Novak Anne J, Grote Deanna et al. CDDO-imidazolide mediated inhibition of malignant cell growth in Waldenstrom macroglobulinemia. Leukemia Research 2008-01-01 [PMID: 18468679] (WB, Human)
• Heazlewood, C et al. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med;5(3):e54. 2008-03-04 [PMID: 18318598]
• Dror V, Kalynyak TB, Bychkivska Y et al. Glucose and endoplasmic reticulum calcium channels regulate HIF-1beta via presenilin in pancreatic beta-cells. J Biol Chem;283(15):9909-16. 2008-04-11 [PMID: 18174159]
• Alejandro EU, Johnson JD. Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic beta-cell apoptosis. J Biol Chem 283(4):2407-17. 2008-01-25 [PMID: 18006502]
• Greer, EL et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem 282(41):30107-19. 2007-10-12 [PMID: 17711846]
• Zhang, S et al. OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms. Clin Cancer Res 13 (16):4750-8. 2007-08-15 [PMID: 17699852]
• Ougolkov, A et al. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 110(2):735-42. 2007-07-15 [PMID: 17463171]
• Park, K et al. Conditional neuronal simian virus 40 T antigen expression induces Alzheimer-like tau and amyloid pathology in mice. J Neurosci;27(11):2969-78. 2007-03-14 [PMID: 17360920]
• Dennis, Vida A et al. Interleukin-10 anti-inflammatory response to Borrelia burgdorferi, the agent of Lyme disease: a possible role for suppressors of cytokine signaling 1 and 3. Infect Immun 74(10):5780-9. 2006-10-01 [PMID: 16988256]
• Abramovich D, Parborell F, Tesone M. Effect of a vascular endothelial growth factor (VEGF) inhibitory treatment on the folliculogenesis and ovarian apoptosis in gonadotropin-treated prepubertal rats. Biol Reprod 75(3):434-41. 2006-09-01 [PMID: 16775226]
• Rice, PL et al Rice PL, Peters SL, Beard KS, Ahnen DJ. Sulindac independently modulates extracellular signal-regulated kinase 1/2 and cyclic GMP-dependent protein kinase signaling pathways. Mol Cancer Ther 5(3):746-54. 2006-03-01 [PMID: 16546990]
• Csiszar, A et al. Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype. Am J Pathol;168(2):629-38. 2006-02-01 [PMID: 16436676]
• Moiseyev, G et al. RPE65 is the isomerohydrolase in the retinoid visual cycle. Proc Natl Acad Sci U S A 102(35):12413-8. 2005-08-30 [PMID: 16116091]
• Barnidge DR, Jelinek DF, Muddiman DC, Kay NE. Quantitative protein expression analysis of CLL B cells from mutated and unmutated IgV(H) subgroups using acid-cleavable isotope-coded affinity tag reagents. J Proteome Res 2005-07-01 [PMID: 16083281] (WB)
• Nagasawa H, Peng Y, Wilson PF et al. Role of homologous recombination in the alpha-particle-induced bystander effect for sister chromatid exchanges and chromosomal aberrations. Radiat Res. 2005-08-01 [PMID: 16038585] (WB, Hamster)
• Liu, X, Manser, T. Antinuclear antigen B cells that down-regulate surface B cell receptor during development to mature, follicular phenotype do not display features of anergy in vitro. J Immunol 174(8):4505-15. 2005-04-15 [PMID: 15814671]
• Peng Y, Woods RG, Beamish H et al. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM. Cancer Res. 2005-03-01 [PMID: 15753361] (WB, Human)
• Sung, S et al. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. Am J Pathol;165(6):2197-206. 2004-12-01 [PMID: 15579461]
• Adler, S et al. Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. Am J Physiol Renal Physiol;287(5):F907-13. 2004-11-01 [PMID: 15475543]
• Chong, V et al. Differential display polymerase chain reaction reveals increased expression of striatal rat glia-derived nexin following chronic clozapine treatment. Pharmacogenomics J 4(6):379-87. 2004-01-01 [PMID: 15354176]
• Mukherjee, P et al. Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res;10(16):5622-9. 2004-08-15 [PMID: 15328205]
• Laughlin, R et al. Involvement of raft-like plasma membrane domains of Entamoeba histolytica in pinocytosis and adhesion. Infect Immun 72(9):5349-57. 2004-09-01 [PMID: 15322032]
• Watters, JW et al. Genome-wide discovery of loci influencing chemotherapy cytotoxicity. PNAS 101:11809-11814. 2004-01-01 [PMID: 15282376]
• Dietz, A et al. Imatinib mesylate inhibits T-cell proliferation in vitro and delayed-type hypersensitivity in vivo. Blood 104(4):1094-9. 2004-08-15 [PMID: 15100154]
• Hawkins BS, Fischer LJ. Inhibition of insulin synthesis by cyproheptadine: effects on translation. Toxicol Sci79(2):258-65. 2004-06-01 [PMID: 15056814]
• Thornton, M et al. Degradation of NF-kappa B in T cells by gangliosides expressed on renal cell carcinomas. J Immunol172(6):3480-90. 2004-03-15 [PMID: 15004148] (WB, Human)
• Sun, D et al. Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats. Am J Physiol Heart Circ Physiol;286(6):H2249-56. 2004-06-01 [PMID: 14751861]
• Adler, S et al. Oxidant stress leads to impaired regulation of renal cortical oxygen consumption by nitric oxide in the aging kidney. J Am Soc Nephrol;15(1):52-60. 2004-01-01 [PMID: 14694157]
• Liao, J et al. Direct reprobing with anti-beta-actin antibody as an internal control for western blotting analysis. Biotechniques;28(2):216-8. 2000-02-01 [PMID: 10683726]
• Gimona, M et al. Beta-actin specific monoclonal antibody. Cell Motil Cytoskeleton;27(2):108-16. 1994-01-01 [PMID: 8162619]
• North, AJ et al. Actin isoform compartments in chicken gizzard smooth muscle cells. J Cell Sci;107 ( Pt 3):445-55. 1994-03-01 [PMID: 8006065]
• North, AJ et al. Calponin is localised in both the contractile apparatus and the cytoskeleton of smooth muscle cells. J Cell Sci;107 ( Pt 3):437-44. 1994-03-01 [PMID: 8006064]

Reviews for beta-Actin Antibody (NB600-501) (29)

Average Rating: 4.8

(Based on 29 reviews)

We have 29 reviews tested in 4 species: Human, Mouse, Rat, Other.

reviewed by: Wei Yang Sit WB Human 05/29/2023

Summary

• Application: Western Blot
• Sample Tested: AGS human gastric adenocarcinoma cell line
• Species: Human
• Lot: 22190126

reviewed by: Verified Customer WB Mouse 02/14/2023

Summary

• Application: Western Blot
• Sample Tested: murine bone marrow derived macrophages
• Species: Mouse
• Lot: 22190126

reviewed by: Verified Customer ICC Mouse 01/22/2022

Summary

• Application: Immunocytochemistry
• Sample Tested: fibroblasts
• Species: Mouse
• Lot: AC-15

reviewed by: Verified Customer WB Human 05/16/2021

Summary

• Application: Western Blot
• Sample Tested: HEK293
• Species: Human
• Lot: 90942

reviewed by: John Morgan WB Human 01/31/2019

Summary

• Application: Western Blot
• Sample Tested: HepG2 CELLS
• Species: Human
• Lot: 106M4825V-4

reviewed by: Anthony Morales WB Rat 01/28/2019

Summary

• Application: Western Blot
• Sample Tested: Mouse brain
• Species: Rat
• Lot: 014M4759

reviewed by: Verified Customer WB Human 01/24/2019

Summary

• Application: Western Blot
• Sample Tested: mouse hepatocytes and HepG2 cells
• Species: Human
• Lot: 105M4825V-3

reviewed by: Luiz Alexandre Magno WB Mouse 07/17/2018

Summary

• Application: Western Blot
• Sample Tested: Brain (corpus striatum),Mouse brain
• Species: Mouse
• Lot: 014M4759

Comments

• Comments: I have used this antibody for several years and it has worked perfectly in our western blots. It works very well at 1:10,00 dilution when loading gels with 30 ug of protein extracts. I congratulate Novus Biologicals for this achievement.

reviewed by: Verified Customer WB Human 02/20/2018

Summary

• Application: Western Blot
• Sample Tested: 293T lysate
• Species: Human
• Lot: 105M4825V-3

reviewed by: Liyong Zhang WB Human 11/25/2017

Summary

• Application: Western Blot
• Sample Tested: mouse hepatocytes and HepG2 cells
• Species: Human
• Lot: 105M4825V-3

reviewed by: Verified Customer WB Human 06/05/2015

Summary

• Application: Western Blot
• Sample Tested: human glioma cells
• Species: Human

reviewed by: Verified Customer WB Human 05/29/2015

Summary

• Application: Western Blot
• Sample Tested: Fibroblast Hs68 cell lysate
• Species: Human

reviewed by: Verified Customer WB Human 03/25/2015

Summary

• Application: Western Blot
• Sample Tested: Caco-2, T84, HCT116, HT29, DU145, BPH1, Hela
• Species: Human

reviewed by: Verified Customer WB Other 02/20/2015

Summary

• Application: Western Blot
• Sample Tested: Whole Skeletal Muscle Lysate
• Species: Other

reviewed by: Sandra Vieira WB Human 01/23/2015

Summary

• Application: Western Blot
• Sample Tested: Whole cell lysates: CHO, GC-1, Hela, Cos-7, SH-SY5Y
• Species: Human
• Lot: 083M4851

reviewed by: Liyong Zhang WB Mouse 07/01/2014

Summary

• Application: Western Blot
• Species: Mouse

reviewed by: Beatrice Gini WB Human 12/02/2013

Summary

• Application: Western Blot
• Sample Tested: human brain cells
• Species: Human

reviewed by: Verified Customer WB Human 12/21/2011

Summary

• Application: Western Blot
• Sample Tested: Human cancer cell line
• Species: Human

reviewed by: Verified Customer WB Mouse 12/21/2011

Summary

• Application: Western Blot
• Sample Tested: Mouse BALB/c macrophage cell line
• Species: Mouse

reviewed by: Verified Customer WB Mouse 12/14/2011

Summary

• Application: Western Blot
• Sample Tested: Mouse
• Species: Mouse

reviewed by: Verified Customer WB Human 12/08/2011

Summary

• Application: Western Blot
• Sample Tested: Human
• Species: Human

reviewed by: Verified Customer WB Rat 12/06/2011

Summary

• Application: Western Blot
• Sample Tested: Rat
• Species: Rat

reviewed by: Verified Customer WB Human 12/05/2011

Summary

• Application: Western Blot
• Sample Tested: Human
• Species: Human

reviewed by: Verified Customer WB Mouse 11/30/2011

Summary

• Application: Western Blot
• Sample Tested: mouse brain
• Species: Mouse

reviewed by: Verified Customer WB Human 11/21/2011

Summary

• Application: Western Blot
• Sample Tested: Human Cell lines
• Species: Human

reviewed by: Verified Customer WB Other 11/09/2011

Summary

• Application: Western Blot
• Sample Tested: Chicken cell lines
• Species: Other

reviewed by: Wei-I Shiao WB Mouse 09/02/2011

Summary

• Application: Western Blot
• Sample Tested: Mouse Cells
• Species: Mouse

reviewed by: Courtney Kurtz WB Other 08/11/2011

Summary

• Application: Western Blot
• Sample Tested: Ground squirrel small intestinal lysate, Sample Amount: 50 ug
• Species: Other

reviewed by: Verified Customer WB Mouse 08/30/2010

Summary

• Application: Western Blot
• Sample Tested: 293T whole cell lysate, adult neural stem cell whole cell lysate
• Species: Mouse

FAQs for beta-Actin Antibody (NB600-501). (Showing 1 - 10 of 12 FAQs).

1. Why is beta actin used as a loading control in blotting ?
   • Beta actin is a highly-expressed protein found in all cells, and is considered a house keeping protein whose expression is necessary for any cell's proper functioning. For this reason it is used as a loading control to confirm that the same amount of total protein is loaded in each lane of an SDS-PAGE gel so that appropriate comparisons can be made between the actual proteins of interest in different samples.
2. Are the beta-Actin antibodies validated in Simple Western?
   • Yes, we offer a few beta actin antibodies that have been tested in Simple Western: NBP1-47423, NB600-501, NB600-532, NB600-503, and NB100-56874.
3. Do Beta-Actin antibodies come in lyophilized format?
   • ACTB antibodies like MAB8969 AND MAB8929 come in lyophilized form.
4. What is the theoretical molecular weight for Beta-Actin antibodies?
   • The TMW for beta Actin antibodies is approximately 42 kDa.
5. I wanted to know which of the two housekeeping genes B-actin or GAPDH can be used for best results. I intend to do an experiment to determine expression of IL-6 and TNF-alpha in liver and kidney tissues.
   • For homogenized tissue, beta-actin and GAPDH are both fine.
6. We have these Abs: NB120-19481 PPAR gamma Antibody and NB600-501 Beta Actin Antibody (AC-15). The samples that we are analyzing are bovine ones. Please, confirm me if those proteins are valid like positive controls in WB for those antibodies: 1. Beta Actin Recombinant Protein (H00000060-P01). 2. PPAR gamma Protein (NBP1-45290) 3. PPAR gamma Protein (H00005468-P01) 4. PPAR gamma Protein (H00005468-Q01). Or perhaps could be better those lysates: 1. Beta Actin Lysate - L015T6 2. Beta Actin Lysate - H00000060-T02 3. PPAR gamma Lysate - NBL1-14634 4. PPAR gamma Lysate - NBL1-14633 5. PPAR gamma Lysate - NBL1-14635.
   • I recommend the below controls as we have validated these as controls. NB120-19481: 2. PPAR gamma Protein (NBP1-45290) 3. PPAR gamma Protein (H00005468-P01) 4. PPAR gamma Protein (H00005468-Q01). NB600-501: 1. Beta Actin Lysate - L015T6 2. Beta Actin Lysate - H00000060-T02
7. I would like to try the Beta Actin Antibody (AC-15) you have in stock to see if it reacts with fish samples in a Western Blot. Also, I would like to know if you have more information about its reactivity with fish?
   • We have tested that this antibody NB600-501 is reactive with fish. It has been tested with use in black carp. The homology with black carp is 99.0%.
8. Could anti-beta actin antibody recognize the actin derived from mosquito cells (C6/36)?
   • Unfortunately we have not used our antibody with catalogue number NB600-501 to detect beta actin that is derived from mosquito cells. You may however wish to align the peptide immunogen sequence against the full length mosquito beta actin sequence to check the homology. We usually suggest that a homology of greater than 80% is indicative of likely binding. The immunogen sequence for NB600-501 is Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys (DDDIAALVIDNGSGK).
9. May we ask if NB600-501 has been tested with samples from zebrafish?
   • Beta Actin is a highly conserved protein and yes, our Beta Actin antibody (clone AC-15) NB600-501 is guaranteed for Zebrafish species.
10. What is the immunogen sequence of this Beta-Actin antibody?
    • A sequence (Ac-Asp-Asp-Asp-Ile-Ala-Ala-Leu-Val-Ile-Asp-Asn-Gly-Ser-Gly-Lys) within the N-terminal region of beta Actin, conjugated to KLH.
11. Could you please tell me the concentration of beta-Actin Antibody (AC-15) (Nb600-501SS), LOT#077M4757V.
    • This antibody is unpurified (provided as ascites fluid) and hence the antibody concentration is non-quantifiable.
12. I noticed that two of your beta-actin antibodies share the same immunogen and clone number. Could you help me determine the difference between the two: NB600-501 and NB110-67828? 
    • I can confirm that the two antibodies are the same clone, meaning the antibody itself is the same for both products. The principle difference between the two products is the format: NB600-501 is unpurified ascite whereas NB110-67828 is purified.  
Show All 12 FAQs.

Bioinformatics

• Gene Symbol: ACTB