WB, Simple Western, ICC/IF, IPHost:
Hu, Mu, Rt, Po, Ch, Ma, Rb, ZeApplications:
WB, Flow, ICC/IF, IHC, IHC-FrHost:
WB, ELISA, PA
Applications: RNAi, RNAi SP
Actin, gamma 1 (ACTG1) is a member of the actin protein family, a highly conserved protein group with three main isoforms: alpha, beta and gamma. Alpha actins are mainly expressed in muscle tissues where they are a major constituent of the contractile apparatus, whereas beta and gamma actin proteins are widely expressed in most cell types where they are predominantly involved in cell motility and cytoskeleton maintenance. Actin gamma 1 is a cytoplasmic actin isoform usually found in nonmuscle cells.
Actin Gamma 1 antibodies serve as excellent loading controls, due to the proteins' near ubiquitous expressn and strong conservation across most species.
In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cyto-skeleton and as mediators of internal cell motility. Beta actins are highly conserved proteins that are involved in cell motility, structure and integrity. Beta actins are cytoplasmic proteins ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Actin Gamma 1 antibody serves as an excellent loading control.
|Product By Gene ID
- deafness, autosomal dominant 20; deafness, autosomal dominant 26
- cytoskeletal gamma-actin
- actin, cytoplasmic 2
- actin, gamma 1
PTMs for Actin Gamma 1
Learn more about PTMs related to Actin Gamma 1.Ubiquitination
Bioinformatics Tool for Actin Gamma 1
Discover related pathways, diseases and genes to Actin Gamma 1. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.