MyD88 Antibody (4D6)


Western Blot: MyD88 Antibody (4D6) [NBP2-27369] - Normal human bronchial epithelial total cell lysate. Image from verified customer review.
Immunocytochemistry/ Immunofluorescence: MyD88 Antibody (4D6) [NBP2-27369] - Analysis of MyD88 antibody in MCF-7 cells using an isotype control (top) and MyD88 Antibody (bottom) at 5 ug/ml.
Flow (Intracellular): MyD88 Antibody (4D6) [NBP2-27369] - Analysis using the Alexa Fluor (R) 488 conjugate of NBP2-27369. Staining of MyD88 antibody in Jurkat cells using 10 ul (0.5 ug) of MyD88 antibody. Green more
Western Blot: MyD88 Antibody (4D6) [NBP2-27369] - Analysis of MyD88 in A) human ovary, B) human prostate and Jurkat cell lysate in the C) absence and D) presence of immunizing peptide using this antibody. Goat more
Flow Cytometry: MyD88 Antibody (4D6) [NBP2-27369] - Intracellular analysis of MyD88 antibody in Jurkat cells using 0.5 ug. Shaded histogram represents cells without antibody; green represents isotype control; red more

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, Flow, Flow-IC, ICC/IF
1.0 mg/ml

MyD88 Antibody (4D6) Summary

A portion of amino acids 50-100 of human MyD88 was used as the immunogen for this antibody.
IgG1 Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.1 ml PBS
0.05% Sodium Azide
1.0 mg/ml
Protein G purified


  • Western Blot 5-7ug/ml
  • Flow Cytometry 0.5ug/10^6cells~
  • Immunocytochemistry/Immunofluorescence 5ug/ml
  • Flow (Intracellular)
Reviewed Applications
Read 2 Reviews rated 5
NBP2-27369 in the following applications:

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NBP2-27369 in the following applications:

Reactivity Notes

The amino acid sequence used as immunogen is 100% homologous in human (isoform 1: 317 amino acids, isoform 3: 264 aa, isoform 4: 204 aa; isoform 5: 159 aa, CRA_a: 304 aa, CRA_b: 309 aa), gorilla, chimp, rhesus monkey and orangutan, 82% homologous in horse, 73% homologous in dog, 68% homologous in cat and mouse (isoform CRA_a: 314 amino acids, CRA_b: 177 amino acids), and 63% homologous in rat.

Alternate Names for MyD88 Antibody (4D6)

  • MYD88D
  • myeloid differentiation primary response gene (88)
  • myeloid differentiation primary response protein MyD88


MyD88, a protein involved in interleukin-1 (IL-1) mediated signalling was originally isolated as myeloid differentiation primary response gene (3,4). MyD88 possesses a N-terminal death domain similar to cytoplasmic segments of TNF receptor 1, Fas, and C-terminal region related to IL-1 and Toll receptors. Overexpression of MyD88 induces activation the c-Jun N-terminal kinase and NF-kB through its death domain (1,2). The C-terminus of MyD88 interacts with the IL-1 receptor and blocks NF-kB activation induced by IL-1, but not by NF-kB.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MyD88 Antibody (NBP2-27369)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: FLOW.

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Showing Publications 1 - 2 of 2.
Publications using NBP2-27369 Applications Species
Derkow K, Kruger C, Dembny P, Lehnardt S. Microglia Induce Neurotoxic IL-17+ gammadelta T Cells Dependent on TLR2, TLR4, and TLR9 Activation. PLoS ONE. 2015 Aug 20 [PMID:26288016] (FLOW, Mouse) FLOW Mouse
Bauer JMJ. Interferon-b moduliert die Expression von Toll-like Rezeptoren in mononuklearen Blutzellen und induziert Toll-like Rezeptor 7 in plasmazytoiden dendritischen Zellen von Patienten mit Multipler Sklerose. thesis. 2015 Nov 12

Reviews for MyD88 Antibody (NBP2-27369) (2) 52

Average Rating: 5
(Based on 2 reviews)
We have 2 reviews tested in 2 species: Human, Mouse.
We have 2 review tested in 1 application: WB.

Reviews using NBP2-27369:
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Images Ratings Applications Species Date Details
Western Blot MyD88 NBP2-27369
reviewed by:
WB Mouse 10/10/2014


ApplicationWestern Blot
Sample Testedmouse lung
Western Blot MyD88 NBP2-27369
reviewed by:
WB Human 09/25/2014


ApplicationWestern Blot
Sample TestedNormal human bronchial epithelial total cell lysate

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MyD88 Antibody (NBP2-27369) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP2-27369AF405
Alexa Fluor (R) 488 Labeled NBP2-27369AF488
Alexa Fluor (R) 488 Labeled NBP2-27266
Alexa Fluor (R) 647 Labeled NBP2-27369AF647
Alexa Fluor (R) 700 Labeled NBP2-27369AF700
Allophycocyanin Labeled NBP2-27369APC
Biotin Labeled NBP2-27369B
DyLight 350 Labeled NBP2-27369UV
DyLight 405 Labeled NBP2-27369V
DyLight 405LS Labeled NBP2-27369V3
DyLight 488 Labeled NBP2-27369G
DyLight 550 Labeled NBP2-27369R
DyLight 650 Labeled NBP2-27369C
DyLight 680 Labeled NBP2-27369FR
DyLight 755 Labeled NBP2-27369IR
HRP Labeled NBP2-27369H
PE Labeled NBP2-27369PE
PerCP Labeled NBP2-27369PCP

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Blogs on MyD88.

TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...  Read full blog post.

MYD88 Expression and Tumorigenesis
MyD88, also called myeloid differentiation primary response gene 88, encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. The innate immune system recognizes the presence of bacterial pathogens thro...  Read full blog post.

TLR7 and Immune Response Regulation
Toll-like receptor 7 (TLR7) is a protein encoded by the TLR7 gene in humans and is a member of TLR family. TLRs controls host immune response against pathogens (e.g. viruses, bacteria and fungi) through recognition of pathogen-associated molecular pat...  Read full blog post.

MYD88: Fanning Inflammation and Immune Responses
Myeloid differentiation primary response gene 88 (MYD88) encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. MYD88 protein functions as an essential signal transducer in the interleukin-1 and in To...  Read full blog post.

MyD88 Antibodies for IL Signaling and Immunity Research
The myeloid differentiation protein MyD88 (myeloid differentiation primary response protein) was originally identified and characterized as a primary upregulated response gene in interleukin-6 mediated myeloid differentiation. Now, MyD88 is known to b...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol MYD88

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