MyD88 Products

Antibodies
MyD88 Antibody
MyD88 Antibody
NB100-56698
Species: Hu, Mu, Rt, Bovine, Equine, Fish, Guinea Pig, Primate, Porcine, Sheep, Xenopus, Zebrafish
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MyD88 Antibody
MyD88 Antibody
NBP1-19785
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP, PAGE
Host: Rabbit Polyclonal
Inhibitors
MyD88 Inhibitor Peptide Set
MyD88 Inhibitor Peptide Set
NBP2-29328
Species: Hu, Mu, Rt, Xp, Ze
Applications: B/N, ELISA, Func-Inh, In vitro, In vivo
Lysates
MyD88 Overexpression Lysate ( ...
MyD88 Overexpression Lysate (Denat...
H00004615-T01
Species: Hu
Applications: WB
MyD88 Overexpression Lysate ( ...
MyD88 Overexpression Lysate (Native)
NBL1-13419
Applications: WB
Proteins
MyD88 Recombinant Protein
MyD88 Recombinant Protein
H00004615-P01
Species: Hu
Applications: WB, ELISA, IP, PA
MyD88 Partial Recombinant Pro ...
MyD88 Partial Recombinant Protein
H00004615-Q01
Species: Hu
Applications: WB, ELISA, PA
MyD88 Recombinant Protein
MyD88 Recombinant Protein
NBP2-23255
Species: Hu
Applications: PAGE
RNAi
MyD88 RNAi
MyD88 RNAi
H00004615-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Myeloid differentiation Marker 88 (MyD88) is a universal adaptor molecule for the Toll/IL1R and is involved in the inflammatory response induced by IL1, IL18 and LPS. MyD88 associates with and recruits IRAK to IL1 receptor complex in response to IL1. This pathway further leads to activation of NFkB. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL1 and IL18, and MyD88 deficient mice lack responses to bacterial product LPS that employs Toll like receptors 2 and 4 as the signaling receptors.

Bioinformatics

Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 4615
Alternate Names
  • myeloid differentiation primary response protein MyD88
  • MYD88D
  • myeloid differentiation primary response gene (88)

Research Areas for MyD88

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Protein Kinase

Bioinformatics Tool for MyD88

Discover related pathways, diseases and genes to MyD88. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related MyD88 Blog Posts

Check out the latest blog posts on MyD88.
TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...    Read more.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
MYD88 Expression and Tumorigenesis
MyD88, also called myeloid differentiation primary response gene 88, encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. The innate immune system recognizes the presence of bacterial pathogens thro...    Read more.
TLR7 and Immune Response Regulation
Toll-like receptor 7 (TLR7) is a protein encoded by the TLR7 gene in humans and is a member of TLR family. TLRs controls host immune response against pathogens (e.g. viruses, bacteria and fungi) through recognition of pathogen-associated molecular pat...    Read more.
MYD88: Fanning Inflammation and Immune Responses
Myeloid differentiation primary response gene 88 (MYD88) encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. MYD88 protein functions as an essential signal transducer in the interleukin-1 and in To...    Read more.
MyD88 Antibodies for IL Signaling and Immunity Research
The myeloid differentiation protein MyD88 (myeloid differentiation primary response protein) was originally identified and characterized as a primary upregulated response gene in interleukin-6 mediated myeloid differentiation. Now, MyD88 is known to b...    Read more.
Read more MyD88 related blogs.