MyD88 Products

MyD88 Antibody [Unconjugated] ...
MyD88 Antibody [Unconjugated]
Species: Mu, Rt
Applications: WB, Simple Western, CyTOF-ready, Flow, ICC/IF
Host: Goat Polyclonal
Formulation Catalog # Availability Price  
Human MyD88 DuoSet ELISA, 15 ...
Human MyD88 DuoSet ELISA, 15 Plate
Species: Hu
Applications: ELISA
Mouse MyD88 ELISA Kit (Colori ...
Mouse MyD88 ELISA Kit (Colorimetric)
Species: Mu
Applications: ELISA
MyD88 Inhibitor Peptide Set
MyD88 Inhibitor Peptide Set
Species: Hu, Mu, Rt, Bv, Xp, Ye, Ze
Applications: ELISA, Flow, Func-Inh, IHC, In vitro, In vivo, B/N
MyD88 Overexpression Lysate
MyD88 Overexpression Lysate
Species: Hu
Applications: WB
MyD88 Antibody Blocking Pepti ...
MyD88 Antibody Blocking Peptide
Applications: AC
Recombinant Human MyD88 GST ( ...
Recombinant Human MyD88 GST (N-Ter...
Species: Hu
Applications: WB, ELISA, IP, PA, AP
Recombinant Human MyD88 His P ...
Recombinant Human MyD88 His Protein
Species: Hu
Applications: PAGE


Myeloid differentiation Marker 88 (MyD88) is a universal adaptor molecule for the Toll/IL1R and is involved in the inflammatory response induced by IL1, IL18 and LPS. MyD88 associates with and recruits IRAK to IL1 receptor complex in response to IL1. This pathway further leads to activation of NFkB. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL1 and IL18, and MyD88 deficient mice lack responses to bacterial product LPS that employs Toll like receptors 2 and 4 as the signaling receptors.


Uniprot Human
Product By Gene ID 4615
Alternate Names
  • MYD88D
  • myeloid differentiation primary response gene (88)
  • myeloid differentiation primary response protein MyD88

Research Areas for MyD88

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Innate Immunity
Protein Kinase

Bioinformatics Tool for MyD88

Discover related pathways, diseases and genes to MyD88. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related MyD88 Blog Posts

Check out the latest blog posts on MyD88.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...    Read more.
MyD88 Antibodies for IL Signaling and Immunity Research
The myeloid differentiation protein MyD88 (myeloid differentiation primary response protein) was originally identified and characterized as a primary upregulated response gene in interleukin-6 mediated myeloid differentiation. Now, MyD88 is known to b...    Read more.
MYD88: Fanning Inflammation and Immune Responses
Myeloid differentiation primary response gene 88 (MYD88) encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. MYD88 protein functions as an essential signal transducer in the interleukin-1 and in To...    Read more.
The role of STING/TMEM173 in gamma and encephalitis Herpes Simplex Virus (HSV)
Stimulator of interferon genes (STING), also known as TMEM173, promotes the production of the interferon’s IFN-alpha and IFN-beta.  STING possesses three functional domains: a cytoplasmic C-terminal tail, a central globular domain, and four N-...    Read more.
TLR7 and Immune Response Regulation
Toll-like receptor 7 (TLR7) is a protein encoded by the TLR7 gene in humans and is a member of TLR family. TLRs controls host immune response against pathogens (e.g. viruses, bacteria and fungi) through recognition of pathogen-associated molecular pat...    Read more.
MYD88 Expression and Tumorigenesis
MyD88, also called myeloid differentiation primary response gene 88, encodes a cytosolic adapter protein that plays an essential role in innate and adaptive immune responses. The innate immune system recognizes the presence of bacterial pathogens thro...    Read more.
Toll-like receptors in the intestinal epithelial cells
By Jamshed Arslan, Pharm. D., PhD. Toll-like receptors (TLRs) are microbe-sensing proteins that act as first responders to danger signals. TLRs help the intestinal epithelial cells (IECs) recognize commensal bacteria ...    Read more.

    Read more.
Read more MyD88 related blogs.