CD31/PECAM-1 Antibody (MEC13.3) [DyLight 488]


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Product Details

Reactivity MuSpecies Glossary
Applications Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Please see the vial label for concentration. If unlisted please contact technical services.

CD31/PECAM-1 Antibody (MEC13.3) [DyLight 488] Summary

mouse endothelial cell line T-end
Membrane; Single-pass type I membrane protein. Cell junction.
IgG2a Kappa
Protein G purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 488
DyLight 488 (A=493, E=518)
50mM Sodium Borate
0.05% Sodium Azide
Please see the vial label for concentration. If unlisted please contact technical services.
Protein G purified


Application Notes
This CD31/PECAM1 Antibody (MEC13.3) is useful for Flow Cytometry, Immunoprecipitation, Immunohistochemical staining of acetone-fixed frozen sections and zinc-fixed paraffin-embedded sections, and in vitro and in vivo blocking of CD31-mediated cell-cell interactions. Please Note: NB600-1475 works well on acetone-fixed frozen sections as well as zinc-fixed paraffin-embedded sections. However, it is not recommended for formalin-fixed paraffin-embedded sections due to inconsistent results. In vivo assay was reported in scientific literature.

Reactivity Notes


Alternate Names for CD31/PECAM-1 Antibody (MEC13.3) [DyLight 488]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • endoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule


CD31/PECAM1 is commonly used as an endothelial marker, particularly in angiogenesis. CD31 is important in assisting placental and endometrial vascular development. However, CD31 is also associated with many negative angiogenic occurrences, particularly those within or related to tumors and other disease lesions. In MS, plasma microparticules carry CD31 and are important in the formation of brain lesions associated with MS. In cardiac angiosarcoma, CD31 presence is indicative of the severity of the disease. In prostate tumor cells, CD31 is upregulated and associated with increased levels of HIF1a, VEGF, and other hypoxic markers. This relationship seems to indicate that when prostate cancer reaches a sufficient state of development that intense angiogenesis must occur in order to support the ongoing growth and survival of the cancer cells. In all, CD31 is a great marker for normal and disease-induced angiogenesis.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB600-1475APC
DyLight 350 Labeled NB600-1475UV
DyLight 405 Labeled NB600-1475V
DyLight 405LS Labeled NB600-1475V3
DyLight 550 Labeled NB600-1475R
DyLight 650 Labeled NB600-1475C
DyLight 680 Labeled NB600-1475FR
DyLight 755 Labeled NB600-1475IR
FITC Labeled NB600-1475F
PE Labeled NB600-1475PE
PerCP Labeled NB600-1475PCP

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Contact Information

Product PDFs


Gene Symbol PECAM1

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