CD31/PECAM-1 Antibody (C31.7) [Alexa Fluor® 700]

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Product Details

Summary
Reactivity Hu, Cm, RbSpecies Glossary
Applications WB, Flow, ICC/IF, IHC-Fr, IHC-P
Clone
C31.7
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 700

CD31/PECAM-1 Antibody (C31.7) [Alexa Fluor® 700] Summary

Immunogen
Human recombinant CD31 protein
Localization
Cell surface and cytoplasmic
Marker
Endothelial Cell Marker
Specificity
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PECAM1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Reactivity Notes

Human, Cynomolgus Monkey and Rabbit. Weakly reacts with Rat. Feedback has been negative on pig kidney paraffin sections.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. This product is provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CD31/PECAM-1 Antibody (C31.7) [Alexa Fluor® 700]

  • adhesion molecule
  • CD31 antigen
  • CD31
  • CD31/EndoCAM
  • endoCAM
  • FLJ34100
  • FLJ58394
  • GPIIA'
  • PECA1
  • PECAM1
  • PECAM-1
  • PECAM-1, CD31/EndoCAM
  • platelet endothelial cell adhesion molecule
  • platelet/endothelial cell adhesion molecule

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CD31/PECAM-1 Antibody (NBP2-33136AF700) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CD31/PECAM-1 Products

Bioinformatics Tool for CD31/PECAM-1 Antibody (NBP2-33136AF700)

Discover related pathways, diseases and genes to CD31/PECAM-1 Antibody (NBP2-33136AF700). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for CD31/PECAM-1 Antibody (NBP2-33136AF700)

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Pathways for CD31/PECAM-1 Antibody (NBP2-33136AF700)

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PTMs for CD31/PECAM-1 Antibody (NBP2-33136AF700)

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Research Areas for CD31/PECAM-1 Antibody (NBP2-33136AF700)

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Blogs on CD31/PECAM-1.

The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...  Read full blog post.

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Contact Information

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Bioinformatics

Gene Symbol PECAM1
Entrez