CCR7 Antibody (150503) [Phycoerythrin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
150503
Clonality
Monoclonal
Host
Mouse
Conjugate
Phycoerythrin

Order Details

CCR7 Antibody (150503) [Phycoerythrin] Summary

Additional Information
Clone 150503 was used by HLDA to establish CD designation
Immunogen
Human CCR7 transfectants
Met1-Pro378
Accession # AAA58615
Specificity
Detects human CCR7.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CCR7
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 4 Reviews rated 4.5
using
FAB197P in the following application:

Publications
Read Publications using
FAB197P in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR7 Antibody (150503) [Phycoerythrin]

  • BLR2
  • BLR2C-C chemokine receptor type 7
  • C-C CKR-7
  • CC-CKR-7
  • CCR7
  • CCR-7
  • CD197 antigen
  • CD197
  • CDw197
  • CDw197CC chemokine receptor 7
  • chemokine (C-C motif) receptor 7
  • CMKBR7
  • CMKBR7chemokine (C-C) receptor 7
  • EBI1
  • EBI1EBV-induced G protein-coupled receptor 1
  • EBV-induced G-protein coupled receptor 1
  • Epstein-Barr virus induced gene 1
  • Epstein-Barr virus induced G-protein coupled receptor
  • Epstein-Barr virus-induced G-protein coupled receptor 1
  • EVI1
  • lymphocyte-specific G protein-coupled peptide receptor
  • MIP-3 beta receptor

Background

CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine. CCL19 and CCL21 are constitutively expressed by high endothelial venule epithelial cells or fibroblastic reticular cells in secondary lymphoid organs. CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK cells, and B cells following inflammatory stimulation. Its expression enables the function of immune cell trafficking to and retention in regional lymph nodes for expansion of the adaptive immune response. Human CCR7 shares 87% amino acid sequence identity with mouse CCR7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAB197P
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Publications for CCR7 Antibody (FAB197P)(57)

We have publications tested in 3 confirmed species: Human, Primate, Primate - Macaca mulatta (Rhesus Macaque).

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(56)
All Applications
Filter By Species
Human
(52)
Primate
(1)
Primate - Macaca mulatta (Rhesus Macaque)
(3)
All Species
Showing Publications 1 - 10 of 57. Show All 57 Publications.
Publications using FAB197P Applications Species
D Kim, G Park, J Huuhtanen, S Lundgren, RK Khajuria, AM Hurtado, C Muñoz-Call, L Cardeñoso, V Gómez-Garc, TH Chen-Liang, S Eldfors, P Ellonen, S Hannula, M Kankainen, O Bruck, A Kreutzman, U Salmenniem, T Lönnberg, A Jerez, M Itälä-Reme, M Myllymäki, MAI Keränen, S Mustjoki Somatic mTOR mutation in clonally expanded T lymphocytes associated with chronic graft versus host disease Nat Commun, 2020;11(1):2246. 2020 [PMID: 32382059] (Flow Cytometry, Human) Flow Cytometry Human
T Tyrinova, O Leplina, S Mishinov, M Tikhonova, E Dolgova, A Proskurina, V Stupack, S Bogachev, A Ostanin, E Chernykh Defective Regulation of Membrane TNF&alpha Expression in Dendritic Cells of Glioblastoma Patients Leads to the Impairment of Cytotoxic Activity against Autologous Tumor Cells Int J Mol Sci, 2020;21(8):. 2020 [PMID: 32326230] (Flow Cytometry, Human) Flow Cytometry Human
K Kurihara, T Fujiyama, P Phadungsak, T Ito, Y Tokura Significance of IL-17A-producing CD8+CD103+ skin resident memory T cells in psoriasis lesion and their possible relationship to clinical course J. Dermatol. Sci., 2019;95(1):21-27. 2019 [PMID: 31300254] (Flow Cytometry, Human) Flow Cytometry Human
E Jimenez Ve, YV Chew, L Nicholson, H Burns, P Anderson, HT Chen, L Williams, K Keung, NT Zanjani, S Dervish, E Patrick, XM Wang, S Yi, W Hawthorne, S Alexander, PJ O'Connell, M Hu Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients PLoS ONE, 2019;14(5):e0217163. 2019 [PMID: 31116766] (Flow Cytometry, Human) Flow Cytometry Human
H Hohtari, O Brück, S Blom, R Turkki, M Sinisalo, PE Kovanen, O Kallioniem, T Pellinen, K Porkka, S Mustjoki Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL Leukemia, 2019;0(0):. 2019 [PMID: 30635636] (Flow Cytometry, Human) Flow Cytometry Human
C Wu, P Yang, H Liu, W Xiao, L Zhao Increased frequency of CCR7+CD4+ T cells from patients with primary Sj�gren's syndrome: An indicator of disease activity rather than of damage severity Cytokine, 2018;110(0):9-17. 2018 [PMID: 29684636] (Flow Cytometry, Human) Flow Cytometry Human
V Giacomet, M Masetti, P Nannini, F Forlanini, M Clerici, GV Zuccotti, D Trabattoni Humoral and cell-mediated immune responses after a booster dose of HBV vaccine in HIV-infected children, adolescents and young adults PLoS ONE, 2018;13(2):e0192638. 2018 [PMID: 29444185] (Flow Cytometry, Human) Flow Cytometry Human
C Ge, R Li, H Song, T Geng, J Yang, Q Tan, L Song, Y Wang, Y Xue, Z Li, S Dong, Z Zhang, N Zhang, J Guo, L Hua, S Chen, X Song Phase I clinical trial of a novel autologous modified-DC vaccine in patients with resected NSCLC BMC Cancer, 2017;17(1):884. 2017 [PMID: 29268708] (Flow Cytometry, Human) Flow Cytometry Human
R Talotta, A Berzi, A Doria, A Batticciot, MC Ditto, F Atzeni, P Sarzi-Putt, D Trabattoni The Immunogenicity of Branded and Biosimilar Infliximab in Rheumatoid Arthritis According to Th9-Related Responses Int J Mol Sci, 2017;18(10):. 2017 [PMID: 29023386] (Flow Cytometry, Human) Flow Cytometry Human
P Thitilertd, L Khowawiset, P Ammaranond, P Poungpairo, V Tantithavo, N Onlamoon Impact of Vaccination on Distribution of T Cell Subsets in Antiretroviral-Treated HIV-Infected Children Dis. Markers, 2017;2017(0):5729639. 2017 [PMID: 28694558] (Flow Cytometry, Human) Flow Cytometry Human
Show All 57 Publications.

Reviews for CCR7 Antibody (FAB197P) (4) 4.54

Average Rating: 4.5
(Based on 4 reviews)
We have 4 reviews tested in 1 species: Human.

Reviews using FAB197P:
Filter by Applications
Flow
(4)
All Applications
Filter by Species
Human
(4)
All Species
Images Ratings Applications Species Date Details
  5
reviewed by:
Anonymous
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23168838
SpeciesHuman

Blocking

Blocking DetailsSee PMID: 23168838

Details

Detection NotesSee PMID: 23168838

Comments

CommentsIndependent review from antibodyresource.com
  5
reviewed by:
Anonymous
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23168838
SpeciesHuman

Blocking

Blocking DetailsSee PMID: 23168838

Details

Detection NotesSee PMID: 23168838

Comments

CommentsIndependent review from antibodyresource.com
  4
reviewed by:
Anonymous
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 19041139
SpeciesHuman

Blocking

Blocking DetailsSee PMID: 19041139

Details

Detection NotesSee PMID: 19041139

Comments

CommentsIndependent review from antibodyresource.com
  4
reviewed by:
Anonymous
Flow Human 01/21/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 20884014
SpeciesHuman

Blocking

Blocking DetailsSee PMID: 20884014

Details

Detection NotesSee PMID: 20884014

Comments

CommentsIndependent review from antibodyresource.comPublished in PMID: 20884014

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for CCR7 Antibody (FAB197P) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 FAB197U
Alexa Fluor 405 FAB197V
Alexa Fluor 488 FAB197G
Alexa Fluor 594 FAB197T
Alexa Fluor 647 FAB197R
Alexa Fluor 700 FAB197N
Alexa Fluor 700 FAB197N
Alexa Fluor 750 FAB197S
Allophycocyanin FAB197A
Allophycocyanin FAB197A
Biotin FAB197B
Fluorescein FAB197F
Fluorescein FAB197F
Phycoerythrin FAB197P
Phycoerythrin FAB197P

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Recent Reviews

4.5
5
2
4
2
3
0
2
0
1
0

 
Anonymous
01/21/2015
Application: Flow
Species: Human

 
Anonymous
01/21/2015
Application: Flow
Species: Human

 
Anonymous
01/21/2015
Application: Flow
Species: Human

Bioinformatics

Gene Symbol CCR7
Uniprot