CCR7 Antibodies
Chemokine receptor 7 (CCR7) is a G-protein coupled receptor (GPCR) that binds chemokine ligands and plays a role in inflammatory and adaptive immune response. CCR7 is a 7-transmembrane spanning protein made of 378 amino acids with a theoretical molecular weight of 42.8 kDa. Together with its ligands, CCR7 helps home T cells to lymphoid tissues to initiate an immune response. CCR7 Antibodies in our catalog have been cited in over 130+ publications and includes a 5-star reviewed antibody. Browse our inventory of recombinant monoclonal, monoclonal, polyclonal, and CCR7-conjugated antibodies. Validated research applications for these CCR7-antibodies include Block/Neutralize, CyTOF-ready, ELISA, Flow Cytometry, ICC, Immunofluorescence, IHC-Frozen, IHC-Paraffin, Immunoprecipitation, and Knockdown Validated Western Blot. Our CCR7 antibodies are reactive in Human, Mouse, Rat, Bovine, Monkey, and more. Each CCR7 antibody is fully covered by Novus’ Guarantee+. Choose the anti-CCR7 antibody best suited for your research needs by viewing the technical details, images, references, reviews, and related products.
Alternate Names for CCR7 Antibodies
anti-CCR7 antibody, anti-BLR2C-C chemokine receptor type 7 antibody, anti-C-C CKR-7 antibody, anti-CC-CKR-7 antibody, anti-CCR-7 antibody, anti-CD197 antibody, anti-CD197 antigen antibody, anti-CDw197CC chemokine receptor 7 antibody, anti-chemokine (C-C motif) receptor 7 antibody, anti-CMKBR7chemokine (C-C) receptor 7 antibody, anti-EBI1EBV-induced G protein-coupled receptor 1 antibody, anti-EBV-induced G-protein coupled receptor 1 antibody, anti-Epstein-Barr virus induced G-protein coupled receptor antibody, anti-Epstein-Barr virus induced gene 1 antibody, anti-Epstein-Barr virus-induced G-protein coupled receptor 1 antibody, anti-EVI1 antibody, anti-lymphocyte-specific G protein-coupled peptide receptor antibody, anti-MIP-3 beta receptor antibody
23 Results for "ccr7" in Primary Antibodies
![Immunohistochemistry-Paraffin: CCR7 Antibody [NB100-712] - M1 and M2 macrophages showed similar expression patterns in cortical bone. IHC staining was performed in sagittal serial sections of medial condyles from 6-week-old rats within the diaphyseal region. Cluster of differentiation 68 (CD68) was selected as a pan marker for the macrophage lineage, including monocytes, macrophages, giant cells, and osteoclasts. iNOS and C-C chemokine receptor type 7 (CCR7) were selected as M1 phenotypic markers, whereas Arginase1 and cluster of differentiation 163 (CD163) were selected as M2 phenotypic markers. Tartrate-resistant acid phosphatase (TRAP) staining was performed as described in Materials and Methods. Quantification of cell numbers according to their location revealed that most of the M1 and M2 cells were not attached to the bone surfaces. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/boneres201719) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NB100-712-img0006.jpg "Immunohistochemistry-Paraffin: CCR7 Antibody [NB100-712] - M1 and M2 macrophages showed similar expression patterns in cortical bone. IHC staining was performed in sagittal serial sections of medial condyles from 6-week-old rats within the diaphyseal region. Cluster of differentiation 68 (CD68) was selected as a pan marker for the macrophage lineage, including monocytes, macrophages, giant cells, and osteoclasts. iNOS and C-C chemokine receptor type 7 (CCR7) were selected as M1 phenotypic markers, whereas Arginase1 and cluster of differentiation 163 (CD163) were selected as M2 phenotypic markers. Tartrate-resistant acid phosphatase (TRAP) staining was performed as described in Materials and Methods. Quantification of cell numbers according to their location revealed that most of the M1 and M2 cells were not attached to the bone surfaces. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/boneres201719) licensed under a CC-BY license.")
![Immunohistochemistry-Paraffin: CCR7 Antibody [NB100-712] - Mouse spleen](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NB100-712-img0001.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NB100-712] - Mouse spleen](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NB100-712-img0004.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NB100-712] - Human spleen](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NB100-712-img0005.jpg)
![Immunohistochemistry: CCR7 Antibody [NB100-712] - M1 expression pattern changed in trabecular bone. Immunohistochemical staining was performed in sagittal serial sections of medial condyles from 6-week-old rats within the epiphyseal region. The region with the solid line indicates areas of interest to be enlarged in the following image. Representative staining with the anticluster of differentiation 68 (CD68) antibody demonstrated that CD68+ cells were either attached (black arrows) or unattached (white arrows) to the bone surfaces with a variety of sizes & shapes (a, b). TRAP+ cells showed multinucleated morphology (black arrows) which is similar to the CD68+ cells (c, d). Inducible nitric oxide synthase-positive (iNOS+) & C-C chemokine receptor type 7-positive (CCR7+) cells (black arrow) were attached to the bone surfaces with an elongated morphology (e, f, i, j). Arginase1+ & cluster of differentiation 163-positive (CD163+) cells (white arrow) represented the predominant population in the reticular connective tissue with similar expression patterns as in the cortical bone (g, h, k, l). No positive staining was found in isotype controls (data not shown). Most of the M1-labeled cells were found attached to bone surfaces instead of M2-labeled cells (m). Representative images from three independent experiments are shown. FOV, field of view. Data shown as the mean±s.d. (*P<0.05). Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/29263936), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-712_goat-polyclonal-ccr7-antibody-310202415532041.jpg)
![Western Blot: CCR7 Antibody (SR36-04) [NBP2-67324] - Analysis of CCR7 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: Jurkat cell lysateLane 2: MCF-7 cell lysate Lane 3: PC-12 cell lysate Lane 4: Daudi cell lysate](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Western-Blot-NBP2-67324-img0009.jpg "Western Blot: CCR7 Antibody (SR36-04) [NBP2-67324] - Analysis of CCR7 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. The primary antibody (1/500) was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: Jurkat cell lysateLane 2: MCF-7 cell lysate Lane 3: PC-12 cell lysate Lane 4: Daudi cell lysate")
![<b>Biological Strategies Validation. </b>Immunocytochemistry/Immunofluorescence: CCR7 Antibody (SR36-04) [NBP2-67324] - Gross and histological appearance of lung excised from 13 weeks of age PyMT transgenic females. CRE treated PyMT transgenic females showed decreased frequency of mammary tumor-derived lung metastases. Immunohistochemistry staining against Ccr7 in lung tissues was done and representative images of tissue sections from each group were taken at 200X and 40X magnification. Scale bars = 50um. Histogram data was presented as mean +/- SEM. * p < 0.05 vs. control. Image collected and cropped by CiteAb from the following publication (//www.mdpi.com/2072-6643/11/2/410), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Immunocytochemistry-Immunofluorescence-NBP2-67324-img0006.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody (SR36-04) [NBP2-67324] - Analysis of paraffin-embedded human tonsil tissue using anti-CCR7 antibody. Counter stained with hematoxylin.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Immunohistochemistry-Paraffin-NBP2-67324-img0004.jpg)
![<b>Biological Strategies Validation. </b>Western Blot: CCR7 Antibody (SR36-04) [NBP2-67324] - Gross and histological appearance of lung excised from 13 weeks of age PyMT transgenic females. CRE treated PyMT transgenic females showed decreased frequency of mammary tumor-derived lung metastases. Level of Ccr7 protein in lung tissues was analyzed by Western blot. Gapdh was used as an internal control. * p < 0.05 vs. control. Image collected and cropped by CiteAb from the following publication (//www.mdpi.com/2072-6643/11/2/410), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Western-Blot-NBP2-67324-img0008.jpg)
![Immunocytochemistry/Immunofluorescence: CCR7 Antibody (SR36-04) [NBP2-67324] - Staining CCR7 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Immunocytochemistry-Immunofluorescence-NBP2-67324-img0001.jpg)
![Immunocytochemistry/Immunofluorescence: CCR7 Antibody (SR36-04) [NBP2-67324] - Staining CCR7 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Immunocytochemistry-Immunofluorescence-NBP2-67324-img0002.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody (SR36-04) [NBP2-67324] - Analysis of paraffin-embedded human spleen tissue using anti-CCR7 antibody. Counter stained with hematoxylin.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Immunohistochemistry-Paraffin-NBP2-67324-img0003.jpg)
![<b>Genetic Strategies Validation. </b>Western Blot: CCR7 Antibody (SR36-04) [NBP2-67324] - Downregulation of CCR7 gene by siRNA inhibits gene expression of MMP9, c-FOS, c-JUN and CCL21 in vitro. Western blot of proteins extracted from MCF7 cell against CCR7 and GAPDH. Image collected and cropped by CiteAb from the following publication (//www.mdpi.com/2072-6643/11/2/410), licensed under a CC-BY license.](http://images.novusbio.com/fullsize/CCR7-Antibody-SR36-04-Knockdown-Validated-NBP2-67324-img0007.jpg)
![Western Blot: CCR7 Antibody (SR36-04) [NBP2-67324] - Curcumae radix extract treatment exhibited anti-metastatic effects on primary tumor of MMTV-PyMT transgenic mouse. (A) Quantitative analysis of real-time PCR was done using genes associated with breast cancer metastasis. The expression levels of Ccr7, c-Fos, Mmp9, Ccl21, & Ccl19 were determined by qRT-PCR. The Hprt gene was used as input control, respectively, * p < 0.05 & ** p < 0.005 vs. control. (B) Western blot of proteins extracted from tumor tissues in the PyMT transgenic model against Ccr7 & Gapdh. Histogram data was presented as mean ± SEM. * p < 0.05 vs. control. (C) Western blot of proteins extracted from tumor tissues against Phosphorylated Akt, Phosphorylated Ampk, Her2, ERalpha, Gapdh & beta -actin. (D) Quantitative analysis of real time PCR was done by using genes associated with apoptosis. The expression levels of Jun, Akt, & Tnf were determined by qRT-PCR. Data are representative of three independent experiments & are expressed as the mean ± SD. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30781353), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nbp2-67324_rabbit-monoclonal-ccr7-antibody-sr36-04-3102024161224.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NBP2-31089] - Hodgkin's disease Reed Sternberg cells.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NBP2-31089-img0005.jpg "Immunohistochemistry-Paraffin: CCR7 Antibody [NBP2-31089] - Hodgkin's disease Reed Sternberg cells.")
![Immunohistochemistry-Paraffin: CCR7 Antibody [NBP2-31089] - Analysis of anti-CCR7 antibody with human tonsil.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NBP2-31089-img0002.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NBP2-31089] - Human lymph node tissue after heat-induced antigen retrieval.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NBP2-31089-img0003.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NBP2-31089] - Lymph node, eosinophilic granuloma Langerhans histiocytes.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NBP2-31089-img0004.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - HLymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0007.jpg "Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - HLymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.")
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Analysis of anti-CCR7 antibody with lymph node at 6 ug/ml.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0001.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Analysis of anti-CCR7 antibody with human bone, eosinophilic granuloma.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0002.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Anti-CCR7 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0003.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Hodgkin's disease Reed Sternberg cells](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0004.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Brain Hypothalamus Neuron](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0005.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS847] - Human lymph node. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS847-img0006.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS848] - Analysis of anti-CCR7 antibody with transfected cells expressing CCR7 at 14 ug/ ml.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS848-img0008.jpg "Immunohistochemistry-Paraffin: CCR7 Antibody [NLS848] - Analysis of anti-CCR7 antibody with transfected cells expressing CCR7 at 14 ug/ ml.")
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS848] - Analysis of anti-CCR7 antibody with transfection control at 14 ug/ml.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS848-img0002.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS848] - Analysis of anti-CCR7 antibody with human tonsil at dilution: 14 ug/ml](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS848-img0007.jpg)
![Immunohistochemistry-Paraffin: CCR7 Antibody [NLS848] - Analysis of anti-CCR7 antibody with human spleen at dilution 14 ug/ml.](http://images.novusbio.com/fullsize/CCR7-Antibody-Immunohistochemistry-Paraffin-NLS848-img0006.jpg)
![Western Blot: CCR7 Antibody [NBP2-41251] - Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 ug/ml.](http://images.novusbio.com/fullsize/CCR7-Antibody-Western-Blot-NBP2-41251-img0001.jpg "Western Blot: CCR7 Antibody [NBP2-41251] - Western blot analysis of CCR7 in human spleen tissue lysate with CCR7 antibody at 1 ug/ml.")
![Immunocytochemistry/ Immunofluorescence: CCR7 Antibody - BSA Free [NBP2-41251] - Immunofluorescence of CCR7 in human spleen tissue with CCR7 antibody at 20 ug/mL.](http://images.novusbio.com/fullsize/nbp2-41251_rabbit-polyclonal-ccr7-antibody-2711202419553080.jpg)
![Immunohistochemistry: CCR7 Antibody - BSA Free [NBP2-41251] - Immunohistochemistry of CCR7 in human spleen tissue with CCR7 antibody at 5 ug/mL.](http://images.novusbio.com/fullsize/nbp2-41251_rabbit-polyclonal-ccr7-antibody-2711202419293815.jpg)
![Western Blot: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis using CD197 mAb against HEK293 (1) and CD197 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-Western-Blot-NBP2-61680-img0004.jpg "Western Blot: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis using CD197 mAb against HEK293 (1) and CD197 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.")
![Flow Cytometry: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis of K562 cells using CCR7 mouse mAb (green) and negative control (red).](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-Flow-Cytometry-NBP2-61680-img0006.jpg)
![Western Blot: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis using CD197 mAb against human CD197 (AA: extra mix) recombinant protein. (Expected MW is 37.5 kDa)](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-Western-Blot-NBP2-61680-img0003.jpg)
![Western Blot: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis using CD197 mouse mAb against C6 (1) cell lysate.](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-Western-Blot-NBP2-61680-img0005.jpg)
![Flow Cytometry: CCR7 Antibody (4B7B8) [NBP2-61680] - Analysis of HL-60 cells using CCR7 mouse mAb (green) and negative control (red).](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-Flow-Cytometry-NBP2-61680-img0002.jpg)
![ELISA: CCR7 Antibody (4B7B8) [NBP2-61680] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](http://images.novusbio.com/fullsize/CCR7-Antibody-4B7B8-ELISA-NBP2-61680-img0001.jpg)
