CCR7 Antibody (150503) [Unconjugated] Summary
Clone 150503 was used by HLDA to establish CD designation
Human CCR7 transfectants
Accession # AAA58615
Detects human CCR7.
|Details of Functionality
ActivityAssaywCitation not found None None None None
<0.10 EU per 1 μg of the antibody by the LAL method.
Test in a species/application not listed above to receive a full credit towards a future purchase.
- Flow Cytometry 0.25 ug/10^6 cells
- Immunohistochemistry 5-25 ug/mL
- Immunocytochemistry 8-25 ug/mL
- Neutralization 1-5 ug/mL
Packaging, Storage & Formulations
|Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for CCR7 Antibody (150503) [Unconjugated]
- BLR2C-C chemokine receptor type 7
- C-C CKR-7
- CD197 antigen
- CDw197CC chemokine receptor 7
- chemokine (C-C motif) receptor 7
- CMKBR7chemokine (C-C) receptor 7
- EBI1EBV-induced G protein-coupled receptor 1
- EBV-induced G-protein coupled receptor 1
- Epstein-Barr virus induced gene 1
- Epstein-Barr virus induced G-protein coupled receptor
- Epstein-Barr virus-induced G-protein coupled receptor 1
- lymphocyte-specific G protein-coupled peptide receptor
- MIP-3 beta receptor
CCR7 (Chemokine Receptor 7; also CD197) is a 7 transmembrane (7TM) G protein-coupled chemokine
receptor for the homeostatic chemokines CCL19/MIP-3 beta and CCL21/6Ckine.
CCL19 and CCL21 are constitutively expressed by high endothelial venule
epithelial cells or fibroblastic reticular cells in secondary lymphoid organs.
CCR7 is upregulated on dendritic cells, naïve and memory T cells, Treg, NK
cells, and B cells following inflammatory stimulation. Its expression enables
the function of immune cell trafficking to and retention in regional lymph
nodes for expansion of the adaptive immune response. Human CCR7 shares 87%
amino acid sequence identity with mouse CCR7.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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