Neuroscience

Deriving neural precursor cells from human induced pluripotent stem cells

By Jennifer Sokolowski, MD, PhD.

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Dorsomorphin dihydrochloride

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Identifying tumoral and stromal transcriptomes that underlie tumor plasticity and stromal neuroinflammatory response in brain metastasis

AIF-1/Iba-1 expression in mouse brain, IHC

By Jamshed Arslan, Pharm. D., PhD.

Probiotics and exercise can slow Alzheimer’s progression by altering composition of gut bacteria

beta amyloid expression in human Alzheimer’s disease hippocampus, IHC

By Jamshed Arslan, Pharm. D., PhD.

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Microglia: pruning shears for homeostatic maintenance in the brain

By Jennifer Sokolowski, MD, PhD.

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resident macrophages

myeloid lineage cells

polycomb repressive complex 2

Jennifer Sokolowski

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TMEM 119 is a specific marker of microglia cells

By Jennifer Sokolowski, MD, PhD.

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resident macrophages

myeloid lineage cells

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The role of Wnts in neuroinflammation

By Michalina Hanzel, PhD

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neurodegeneration

non-canonical WNT

Michalina Hanzel

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RNA-binding protein Staufen1 conspires with Atxn2 in stress granules to cause neurodegeneration by dysregulating RNA metabolism

By Jamshed Arslan Pharm.D.

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Purkinje neurons

neurodegeneration

movement disorder

Losing memory: Toxicity from mutant APP and amyloid beta explain the hippocampal neuronal damage in Alzheimer's disease

By Jamshed Arslan Pharm.D.

The inflammasome: an inflammation-initiating machine, Novus Biologicals

By Stephanie Melchor

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Innate Immunity

neurodegeneration

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Rescuing motor neuronal loss in amyotrophic lateral sclerosis by inhibiting phosphatidylinositol-4 kinase

By Jamshed Arslan Pharm.D.

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