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Microglia

Mechanisms of Neurodegeneration: Neuroinflammation and microglial activation

Alzheimer's Disease and Neuroinflammation Poster, R&D Systems, showing blood vessle and both health and diseased neurons.

By Michalina Hanzel, PhD

Tags: 
Alzheimer’s
Parkinson’s
Huntington’s
Neuroinflammation
Microglia
beta amyloid
trem-2
siglec-3-cd33
Michalina Hanzel

Probiotics and exercise can slow Alzheimer’s progression by altering composition of gut bacteria

beta amyloid expression in human Alzheimer’s disease hippocampus, IHC

By Jamshed Arslan, Pharm. D., PhD.

Tags: 
Neuroscience
Microglia
AIF-1/ iba1
APP
Alzheimer’s
beta amyloid
Jamshed Arslan

Microglia: pruning shears for homeostatic maintenance in the brain

Iba1 expression in mouse fore brain, IHC

By Jennifer Sokolowski, MD, PhD.

Tags: 
Neuroscience
Microglia
Macrophage
resident macrophages
myeloid lineage cells
immune cells
polycomb repressive complex 2
AIF-1/ iba1
MMR
AXL
LC3
CD68
EZH2
SUZ12
EED
RbAp48
JARID2
PHF1
EBP2
Jennifer Sokolowski

TMEM 119 is a specific marker of microglia cells

P2Y12/P2RY12 expression, human cerebral cortex shows cytoplasmic positivity in microglia, IHC

By Jennifer Sokolowski, MD, PhD.

Tags: 
Neuroscience
Microglia
Macrophage
resident macrophages
myeloid lineage cells
immune cells
AIF-1/ iba1
F4/80
CX3CR1
CD11b
CD68
Tmem119
immunology

The inflammasome: an inflammation-initiating machine, Novus Biologicals

ASC/TMS1 expression in Hela cells ICC

By Stephanie Melchor

Tags: 
IL-18
IL-1 beta
ASC/TMS1
Microglia
NLRP1
NLRP3
Caspase-1
ALS
epilepsy
Inflammation
inflammasome
Alzheimer’s
Parkinson’s
Innate Immunity
neurodegeneration
Neuroscience
immunology
Pyroptosis

Monitoring Autophagy in Neurons

Beclin 1 expression in human cerebellum, Purkinje cells IHC

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
Neuroscience
neurodegeneration
Microglia
Alzheimer's
Parkinson's
Huntington's
Bafilomycin
LC3
p62
NBR1
ATG7

MAPK Signaling Links Autophagy and Inflammation

Autophagy signaling pathway

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
Neuroscience
neurodegeneration
Microglia
Alzheimer’s
Parkinson’s
ATG5
ULK1
MAPK
ERK1
p38
c-Jun
AIF-1/Iba1