Stem Cells

Successful Transplantation of Friedreich Ataxia Induced Pluripotent Stem Cell (iPSC)-Derived Sensory Neurons in Dorsal Root Ganglia of Adult Rodents

Transcriptional co-activators Yap1 and Taz control growth and development

Antibody treatment can generate microglia-like cells from bone marrow

Deriving neural precursor cells from human induced pluripotent stem cells

Flow Cytometry Basics for the Non-Expert

Application Focus: New Methods for iPSC Differentiation, Inducing a Mammary Fate

Stemness for Surviving Hypoxia: TGF-beta/Smad Signaling in Multiple Myeloma

Meeting Report: 2nd International Antibody Validation Meeting

Bio-Techne brands Novus Biologicals® and R&D Systems® were proud to support the 2nd International Antibody Validation Meeting held at Bath University, on the 15-16 September, 2016. Almost 100 participants from around the world, including funders, publishers, academics, pharma and antibody manufacturers were in attendance, to share and discuss best practices in research antibody validation and to drive improved antibody validation standards for the global life science community.

Beta Tubulin III and neurogenesis

Beta tubulin III, also known as Tuj-1, is a class III member of the beta tubulin protein family. Beta tubulins are one of two structural components that form our microtubule network.

Cre/Lox: The Genomic Utility Knife

Cre (Cyclization recombination enzyme) is a member of the large family of recombinases. Cre recognizes Lox site loxP, a 34 bp sequence motif from the PI bateriophage. If a DNA segment is flanked by two loxP sites in the same orientation, Cre neatly excises the segment (for later degradation) leaving a single remaining loxP site in the DNA molecule. The Cre/Lox system was first developed in the late 1980's to artificially manipulate gene expression and extensive reviews of the system exist (1).

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