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Alzheimer’s

Staufen1 Overabundance and the Consequent mTOR Hyperactivity in Amyotrophic Lateral Sclerosis, Spinocerebellar Ataxia Type 2, Alzheimer’s, Parkinson’s, and Huntington’s Diseases

3D rendering of neurons as a banner image.

Jamshed Arslan, Pharm D, PhD

Tags: 
Amyotrophic Lateral Sclerosis
ALS
Spinocerebellar Ataxia Type 2
Alzheimer’s
Parkinson’s
Huntington’s
neurodegeneration
Autophagy
Neurons
Staufen
TOR/mTOR
Jamshed Arslan

HIV-associated neurocognitive disorders involve extracellular Nef-induced modification of lipid rafts and redistribution of Alzheimer’s disease-related proteins

Immunohistochemical staining of paraffin-embedded ovarian cancer tissue sample with lipid-related protein Apolipoprotein E/ApoE.

Jamshed Arslan, Pharm D, PhD

Tags: 
Alzheimer’s
Cholesterol
HIV
Human Immunodeficiency Virus
HAND
Lipid Raft
neurodegeneration
Neurons
Parkinson’s
ABCA1
Acetylcholinesterase/ACHE
alpha Synuclein
APP
Beta Amyloid 42
Tau
Jamshed Arslan

Mechanisms of Neurodegeneration: Neuroinflammation and microglial activation

Alzheimer's Disease and Neuroinflammation Poster, R&D Systems, showing blood vessle and both health and diseased neurons.

By Michalina Hanzel, PhD

Tags: 
Alzheimer’s
Parkinson’s
Huntington’s
Neuroinflammation
Microglia
beta amyloid
trem-2
siglec-3-cd33
Michalina Hanzel

Mechanisms of Neurodegeneration: Mitochondrial Dysfunction and Oxidative Stress

3D image of dopaminergic neurons shown in green, Bio-Techne.

By Michalina Hanzel, PhD

Tags: 
Alzheimer’s
Parkinson’s
Huntington’s
Autophagy
Alpha-Synuclein
ndufa1
Dopamine
Dopamine D1 R/DRD1
Oxidative Stress
Reactive Oxygen Species
Michalina Hanzel

Mechanisms of Neurodegeneration: Protein aggregation and failure of autophagy

Alzheimer’s disease video Novus Biologicals

By Michalina Hanzel, PhD

Tags: 
Alzheimer’s
Parkinson’s
Huntington’s
beta-amyloid
Presenilin-1
macroautophagy
Autophagy
ATG9A
mTOR
Huntingtin
Alpha-Synuclein
beclin-1
APP
Michalina Hanzel

Probiotics and exercise can slow Alzheimer’s progression by altering composition of gut bacteria

beta amyloid expression in human Alzheimer’s disease hippocampus, IHC

By Jamshed Arslan, Pharm. D., PhD.

Tags: 
Neuroscience
Microglia
AIF-1/ iba1
APP
Alzheimer’s
beta amyloid
Jamshed Arslan

The inflammasome: an inflammation-initiating machine, Novus Biologicals

ASC/TMS1 expression in Hela cells ICC

By Stephanie Melchor

Tags: 
IL-18
IL-1 beta
ASC/TMS1
Microglia
NLRP1
NLRP3
Caspase-1
ALS
epilepsy
Inflammation
inflammasome
Alzheimer’s
Parkinson’s
Innate Immunity
neurodegeneration
Neuroscience
immunology
Pyroptosis

MAPK Signaling Links Autophagy and Inflammation

Autophagy signaling pathway

By Christina Towers, PhD.

Tags: 
Autophagy
autophagosome
Lysosome
Neuroscience
neurodegeneration
Microglia
Alzheimer’s
Parkinson’s
ATG5
ULK1
MAPK
ERK1
p38
c-Jun
AIF-1/Iba1