IRE1α Regulates Dendritic Cell Function in Response to Viral Infection

The NLRP3 Inflammasome: Macrophage Activator & Pathology Driver

Immune Cell Metabolic Flux Influences Type I Diabetes

Lipopolysaccharide from gut microbiome localizes in human atherosclerotic plaques and promotes TLR4-mediated oxidative stress

Microglia: pruning shears for homeostatic maintenance in the brain

TMEM 119 is a specific marker of microglia cells

CD16 - Find me on macrophages, neutrophils and NK cells

CD16 is a lymphocyte Fc gamma type III low-affinity receptor for IgG and is represented by two similar genes, CD16A (Fc gamma RIII A) and CD16B (Fc gamma RIIIB). CD16A exists as a heterooligomeric polypeptide-anchored form in macrophages and NK cells. CD16B exists as a monomeric glycosylphosphatidylinositol (GPI)-anchored form in neutrophils. CD16 binds IgG in the form of immune complexes or free antibody. It exhibits preferential binding to IgG1 and IgG3 isotypes, with minimal binding of IgG2 and IgG4.