This antibody is stable for greater than six months when held at -20 °C in a
manual defrost freezer or at -70 °C. Upon thawing, the antibody can be
stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid
repeated freeze-thaw cycles.
A liquid formulation in physiologic saline with 0.1% NaN3.
0.1% Sodium Azide
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for VDR/NR1I1/Vitamin D Receptor Antibody (H4537) [Unconjugated]
NR1I1Nuclear receptor subfamily 1 group I member 11,25-dihydroxyvitamin D3 receptor
vitamin D1,25- dihydroxyvitamin D3 receptor
vitamin D3 receptor
Vitamin D Receptor (VDR; NR1I1) is a member of the Steroid Receptor family
related to the Pregnane X Receptor (PXR) and Constitutive Androstane
Receptors (CARs). The natural ligand of VDR is 1, 25 di-hydroxyvitamin D3.
VDR is expressed in osteoblasts, osteocytes, osteoclasts, bone, bone marrow,
thymus and small intestine. VDR plays critical roles in calcium homeostasis,
bone development and mineralization, as well as control of cell growth and
differentiation. Retnoid X Receptors (RXRs) are the major partners for VDR
since by heterodimerizing with VDR, they increase their DNA-binding affinity
and select the correct spacing of direct repeat elements.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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