This antibody is stable for greater than six months when stored at -20 °C in a
manual defrost freezer or at -70 °C. Upon thawing, the antibody can be
stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid
repeated freeze-thaw cycles.
A liquid formulation in physiologic saline with 0.1% NaN3.
0.1% Sodium Azide
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for PXR/NR1I2 Antibody (H4417) [Unconjugated]
nuclear receptor subfamily 1 group I member 2
nuclear receptor subfamily 1, group I, member 2
Orphan nuclear receptor PAR1
Orphan nuclear receptor PXR
Pregnane X receptor
Steroid and xenobiotic receptor
Pregnane X Receptor (PXR; also known as SXR and NR1I2) is a 50 kDa
member of the Nuclear Receptor (NR1) subfamily of the Nuclear Hormone
Receptor family. It is a product of the PXR gene that gives rise to two basic
isoforms; a 434 amino acid (aa) PXR1 form and 473 aa PXR2 form. PXR2
differs from PXR1 in that PXR2 contains a 39 aa N-terminal extension. Six
PXR1 isoforms have been reported (Swiss Protein Accession # 075469). The
anti-human PXR antibody recognizes all isoforms except the "B" isoforms
which show a deletion of amino acids 1 - 55 (MEVRP...FNVM). PXR forms a
heterodimer with Retinoid X Receptor (RXR) and binds pregnanolone.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
Review this Product
Be the first to review our PXR/NR1I2 Antibody (H4417) [Unconjugated] and receive a gift card or discount.
PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.