Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P
Host: Rabbit Monoclonal
WB, IHC, IP, ELISAHost:
Species: Hu, Rt
Applications: WB, Flow, ICC/IF
Host: Rabbit Polyclonal
Applications: WB, ELISA, PA, PAGE, AP
Applications: WB, ELISA, PA, AP
Vitamin D Receptor encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.
Research Areas for VDR/NR1I1/Vitamin D Receptor
Find related products by research area and learn more about each of the different research areas below.Signal Transduction
Bioinformatics Tool for VDR/NR1I1/Vitamin D Receptor
Discover related pathways, diseases and genes to VDR/NR1I1/Vitamin D Receptor. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.