SIGIRR Antibody - BSA Free

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Western Blot: SIGIRR Antibody [NB100-56890] - Analysis of human SIGIRR in 15 ugs of (A) human kidney and (B) mouse kidney cell lysate using this antibody at 0.5 ug/ml.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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Catalog# & Formulation Size Price

SIGIRR Antibody - BSA Free Summary

Immunogen
This antibody was developed against a synthetic peptide corresponding to amino acids 334-358 of human SIGIRIR.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SIGIRR
Purity
Protein G purified
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Applications/Dilutions

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein G purified

Alternate Names for SIGIRR Antibody - BSA Free

  • IL-1R8
  • SIGIRR
  • single Ig IL-1-related receptor
  • Single Ig IL-1R-related molecule
  • single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
  • single immunoglobulin domain IL1R1 related
  • Single immunoglobulin domain-containing IL1R-related protein
  • TIR8
  • TIR8MGC110992
  • Toll/interleukin-1 receptor 8

Background

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). TIR8, also know as single Ig IL-1 receptor, is a member of the IL-1/TLR superfamily (2). TIR8 acts as intracellular decoy to inhibit NF-kappaB activation by members of the IL-1/TLR family (3, 4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SIGIRR
Entrez
Uniprot