Mouse IL-18/IL-1F4 ELISA

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
HRP

Order Details

Mouse IL-18/IL-1F4 ELISA Summary

Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il18

Applications/Dilutions

Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using 7625.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse IL-18/IL-1F4 ELISA

  • Iboctadekin
  • IFN-gamma-inducing factor
  • IGIF
  • IGIFIL-1 gamma
  • IL18
  • IL-18
  • IL-18MGC12320
  • IL-1F4
  • IL1F4iboctadekin
  • IL-1g
  • Interferon gamma-inducing factor
  • interleukin 18 (interferon-gamma-inducing factor)
  • Interleukin-1 gamma
  • interleukin-18

Background

Interleukin 18 (IL-18), also known as interferon-gamma-inducing factor (IGIF) and IL-1γ, is a cytokine which shares biologic activities with IL-12 and structural similarities with the IL-1 family of proteins. IL-18 was originally cloned from liver cells and has since been shown to be expressed by monocyte/macrophages, osteoblasts and keratinocytes. Caspase-1 (IL-1 beta-converting enzyme) has been implicated in the physiological processing of pro-IL-18 to IL-18. Similarly to IL-12, human IL-18 has been shown to enhance NK cell activity in PBMC cultures. Human IL-18 has also been found to induce the production IFN-γ and GM-CSF while inhibiting the production of IL-10 by PBMC. On enriched human T cells, human IL-18 can enhance Th1 cytokine production and stimulate cell proliferation via an IL-2-dependent pathway. In the mouse system, IL-18 has been shown to be a costimulatory factor for the activation of Th1, but not Th2, cells. IL-18 was found to selectively enhance the FasL-mediated cytotoxicity of Th1, but not Th0 or Th2, cells. IL-18 has also been shown to induce activated B cells to produce IFN-γ that inhibits IgE production.

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Publications for IL-18/IL-1F4 (7625)(41)

We have publications tested in 2 confirmed species: Mouse, Rat.


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Mouse
(39)
Rat
(1)
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Showing Publications 1 - 10 of 41. Show All 41 Publications.
Publications using 7625 Applications Species
X Wu, S Pan, W Luo, Z Shen, X Meng, M Xiao, B Tan, K Nie, T Tong, X Wang Roseburia�intestinalis?derived flagellin ameliorates colitis by targeting miR?223?3p?mediated activation of NLRP3 inflammasome and pyroptosis Mol Med Rep, 2020;0(0):. 2020 [PMID: 32700754] (Mouse) Mouse
G de la Rosa, AI Gómez, MC Baños, P Pelegrín Signaling Through Purinergic Receptor P2Y2 Enhances Macrophage IL-1&beta Production Int J Mol Sci, 2020;21(13):. 2020 [PMID: 32630144] (Mouse) Mouse
LR Ling, DH Zheng, ZY Zhang, WH Xie, YH Huang, ZX Chen, XZ Wang, D Li Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes Oncol Lett, 2020;19(4):2861-2869. 2020 [PMID: 32218840] (Mouse) Mouse
C Rumfield, I Hyseni, JW McBride, DH Walker, R Fang Activation of ASC Inflammasome Driven by TLR4 Contributes to Host Immunity against Rickettsial Infection Infect. Immun., 2020;0(0):. 2020 [PMID: 32014896] (Mouse) Mouse
SL Wang, BZ Shao, SB Zhao, X Chang, P Wang, CY Miao, ZS Li, Y Bai Intestinal autophagy links psychosocial stress with gut microbiota to promote inflammatory bowel disease Cell Death Dis, 2019;10(6):391. 2019 [PMID: 31564717]
RP Semper, M Vieth, M Gerhard, R Mejías-Luq Helicobacter pylori Exploits the NLRC4 Inflammasome to Dampen Host Defenses J. Immunol., 2019;0(0):. 2019 [PMID: 31511355] (Mouse) Mouse
R Chen, L Zeng, S Zhu, J Liu, HJ Zeh, G Kroemer, H Wang, TR Billiar, J Jiang, D Tang, R Kang cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis Sci Adv, 2019;5(5):eaav5562. 2019 [PMID: 31131320] (Mouse) Mouse
D Kurundkar, AR Kurundkar, NB Bone, EJ Becker, W Liu, B Chacko, V Darley-Usm, JW Zmijewski, VJ Thannickal SIRT3 diminishes inflammation and mitigates endotoxin-induced acute lung injury JCI Insight, 2019;4(1):. 2019 [PMID: 30626741] (Mouse) Mouse
AP Perera, R Fernando, T Shinde, R Gundamaraj, B Southam, SS Sohal, AAB Robertson, K Schroder, D Kunde, R Eri MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice Sci Rep, 2018;8(1):8618. 2018 [PMID: 29872077] (Mouse) Mouse
J Zhu, L Chen, Y Qi, J Feng, L Zhu, Y Bai, H Wu Protective effects of Erigeron breviscapus Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models Mol. Vis., 2018;24(0):315-325. 2018 [PMID: 29769797] (Rat) Rat
Show All 41 Publications.

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Product General Protocols

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FAQs for IL-18/IL-1F4 (7625). (Showing 1 - 1 of 1 FAQs).

  1. wondering what the difference is between your quantikine and duo set elisas?
    • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

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Bioinformatics

Gene Symbol Il18