LEDGF Antibody

Images

 
Immunohistochemistry: LEDGF Antibody [NB110-40560] - Sample: FFPE sections of human lung carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-fs18 LEDGF/p75 fs20 used at a ...read more
Immunohistochemistry: LEDGF Antibody [NB110-40560] - Sample: FFPE sections of human lung carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-fs18 LEDGF/p75 fs20 used at a ...read more
Immunoprecipitation: LEDGF Antibody [NB110-40560] - Detection of Human LEDGF/p75 on HeLa whole cell lysate using NB110-40560 used for IP at 3 mcg/mg lysate. LEDGF/p75 was also IPed by another rabbit anti-LEDGF/p75 ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, IP, WB (-)
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

LEDGF Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 225 and 275 of human Lens Epithelium Derived Growth Factor/Transcriptional Coactivator p75 using the numbering given in entry NP_150091.2 (GeneID 11168).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PSIP1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
Optimal dilution to be determined by the researcher. For western blot, use rabbit anti-LEDGF Antibody NB110-40561
Publications
Read Publications using NB110-40560.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LEDGF Antibody

  • CLL-associated antigen KW-7
  • Dense fine speckles 70 kDa protein
  • DFS 70
  • DFS70
  • LEDGF
  • LEDGFDFS 70
  • Lens epithelium-derived growth factor
  • MGC74712
  • p52
  • p75
  • PAIP
  • PC4 and SFRS1 interacting protein 1
  • PC4 and SFRS1 interacting protein 2
  • PC4 and SFRS1-interacting protein
  • PSIP1
  • PSIP2
  • transcriptional coactivator p52/p75
  • Transcriptional coactivator p75/p52

Background

The human p75 protein is a non TAF transcription coactivator that mediates activator dependent transcription by RNA polymerase II in vitro through most tested activators. Although p75 and p52 are derived from alternatively splicing of a single gene and share most coding sequence, they reveal different function in several aspects. In addition to functioning as a transcription coactivator, p75 has been reported to be involved in regulating growth of epithelial cells, pathogenesis of atopic dermatitis and activity of HIV1 integrase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu
Applications: IHC, IP, WB (-)

Publications for LEDGF Antibody (NB110-40560)(5)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PSIP1
Entrez
Uniprot